Morphine Sulfate Injection, Solution, Concentrate while Breastfeeding

Q: My health care provider has asked me to use Morphine Sulfate Injection, Solution, Concentrate , what to do?

Morphine Sulfate Injection, Solution, Concentrate comes in category of low risk and if your doctor is aware that you are breastfeeding it should be ok to use without much concerns.

Q: If I am using Morphine Sulfate Injection, Solution, Concentrate , will my baby need extra monitoring?

Not much monitoring required while using Morphine Sulfate Injection, Solution, Concentrate

There are high number of clear evidence that breastfeeding provides best nutrition that you can give to your baby. It is also evident that lactation is good for mothers health as well. Evolution has designed breastfeeding in a way that it caters all nutritional need of your child. However modern medicine is quite new for evolution, that is why mothers body is not well prepared to filter unnecessary chemical found in medicines. It becomes a necessity to figure out which drug is safe and which drug is dangerous for your newborn while nursing. In this article we will understand function of Morphine Sulfate Injection, Solution, Concentrate and its suitability with breastfeeding.

What is Morphine Sulfate Injection, Solution, Concentrate used for?

Morphine sulfate is indicated for the relief of severe pain. It is used preoperatively to sedate the patient and allay apprehension, facilitate anesthesia induction and reduce anesthetic dosage. It is likewise effective in the control of post-operative pain. The use of morphine for the relief of pain should be reserved for the more severe manifestations of pain, as in myocardial infarction, severe injuries, or in severe chronic pain associated with terminal cancer after all non-narcotic analgesics have failed. Effective analgesic therapy of severe chronic pain associated with terminal cancer continues to be a difficult problem. Intermittent administration of intramuscular morphine may be effective; however, the mode of therapy has significant limitations. Morphine has a short plasma half-life of 2.5 to 3.0 hours; therefore, frequent administration (every 1 to 2 hours) often becomes necessary to control severe pain associated with cancer. Tolerance develops to the analgesic effects and increasingly higher doses of morphine are required to produce analgesia. The higher morphine doses produce significant and often life-threatening side effects (see ADVERSE REACTIONS). The peak and trough effects produced by intermittent administration cause fluctuations in pain control. Repeated intramuscular injections are frequently unacceptable due to the lack of muscle mass in the debilitated patient, the tendency for bruising and bleeding at the injection site, and the anxiety and pain associated with the injection. Continuous intravenous infusion of morphine (see DOSAGE AND ADMINISTRATION) has been employed as an alternative to traditional modes of administration. Lower doses of morphine produce uniform pain control because a steady morphine concentration is maintained. Titration of the dosage to the patient's needs is easily achieved by adjusting the infusion rate. The lag time between the patient's request for pain medication and administration of the dose and the amount of nursing time necessary for preparation and administration of frequent doses are reduced. The degree of respiratory depression and sedation may be decreased, and the anxiety experienced by the patient in anticipation of intramuscular administration is avoided. Some Investigators feel that tolerance to the analgesic effects may develop more slowly with continuous intravenous infusion. In addition to analgesia, the drug may relieve anxiety and reduce left ventricular work by reducing preload pressure. Morphine is also used in the therapy of dyspnea associated with acute left ventricular and pulmonary edema. Care must be taken to avoid inducing respiratory depression in such patients. For open-heart surgery, especially in high risk patients with cardiac disease, some anesthesiologists use morphine to produce anesthesia.

Is using Morphine Sulfate Injection, Solution, Concentrate unsafe in breastfeeding? Can there be bad consequences for baby if I use it while breastfeeding?

Morphine Sulfate Injection, Solution, Concentrate low risk for breastfeeding

Morphine sulfate is the one and only active ingredient present in Morphine Sulfate Injection, Solution, Concentrate. Morphine sulfate in itself is a low risk drug for lactation so it is easy to understand that Morphine Sulfate Injection, Solution, Concentrate also comes in category of Low Risk item while breastfeeding. Below is the summary of Morphine sulfate in breastfeeding.

Morphine Sulfate Injection, Solution, Concentrate Breastfeeding Analsys

Morphine sulfate while Breastfeeding

Low Risk

CAS Number: 57-27-2

Excretion into breast milk is low (even lower when administered through Epidural Anesthesia). In addition, a low oral bioavailability makes that the amount present in the infant's plasma due to absorption from milk by the gut is low. Even though, level of drug has been found in the plasma of infants from treated mothers, harmful effects in the infants were not reported. Levels in the milk are lower and side-effects are fewer among infants whose mothers were treated with Morphine than with Pethidine. Some authorities consider Morphine as the elective opioid medication for breastfeeding mothers. Analgesia used during the birth process is related to a brief delayed of stage II of Lactogenesis (milk come-in). Morphine increases Prolactin level and may decrease Oxytocin level, but it would not be determinant for already established lactations. Avoidance of repetitive or chronic use and follow-up for somnolence and adequacy of infant nourishment is recommended. Bed-sharing should be avoid whenever this medication is used by parents. The American Academy of Pediatrics rates it as compatible with breastfeeding.

Morphine Sulfate Injection, Solution, Concentrate Breastfeeding Analsys - 2

Morphine sulfate while Breastfeeding

CAS Number: 57-27-2

Morphine Sulfate Injection, Solution, Concentrate and breastfeeding

Epidural morphine given to mothers for postcesarean section analgesia results in trivial amounts of morphine in their colostrum and milk. Intravenous or oral doses of maternal morphine in the immediate postpartum period result in higher milk levels than with epidural morphine. Labor pain medication may delay the onset of lactation. Maternal use of oral narcotics during breastfeeding can cause infant drowsiness, central nervous system depression and even death, although low-dose morphine might be preferred over other opiates.[1] Newborn infants seem to be particularly sensitive to the effects of even small dosages of narcotic analgesics. Once the mother's milk comes in, it is best to provide pain control with a nonnarcotic analgesic and limit maternal intake of morphine to a 2 to 3 days at a low dosage with close infant monitoring, especially in the outpatient setting.[2] If the baby shows signs of increased sleepiness (more than usual), difficulty breastfeeding, breathing difficulties, or limpness, a physician should be contacted immediately.

Is Morphine Sulfate Injection, Solution, Concentrate safe while breastfeeding

What should I do if I am breastfeeding mother and I am already exposed to Morphine Sulfate Injection, Solution, Concentrate?

Morphine Sulfate Injection, Solution, Concentrate is in the category of low risk, if you have already used it then its not a big deal if health and behavior of baby is good. However your health care provider shall be aware of the fact that you have used Morphine Sulfate Injection, Solution, Concentrate so you should inform him based on your convenience.

My health care provider has asked me to use Morphine Sulfate Injection, Solution, Concentrate, what to do?

Morphine Sulfate Injection, Solution, Concentrate comes in category of low risk and if your doctor is aware that you are breastfeeding it should be ok to use without much concerns.

If I am using Morphine Sulfate Injection, Solution, Concentrate, will my baby need extra monitoring?

Not much monitoring required while using Morphine Sulfate Injection, Solution, Concentrate

Who can I talk to if I have questions about usage of Morphine Sulfate Injection, Solution, Concentrate in breastfeeding?

US
National Womens Health and Breastfeeding Helpline: 800-994-9662 (TDD 888-220-5446) 9 a.m. and 6 p.m. ET, Monday through Friday

UK
National Breastfeeding Helpline: 0300-100-0212 9.30am to 9.30pm, daily
Association of Breastfeeding Mothers: 0300-330-5453
La Leche League: 0345-120-2918
The Breastfeeding Network supporter line in Bengali and Sylheti: 0300-456-2421
National Childbirth Trust (NCT): 0300-330-0700

Australia
National Breastfeeding Helpline: 1800-686-268 24 hours a day, 7 days a week

Canada
Telehealth Ontario for breastfeeding: 1-866-797-0000 24 hours a day, 7 days a week