Morphine Sulfate Extended-release | Morphine Sulfate Tablet, Extended Release Breastfeeding
Modern medicine has evolved so much so that sooner or later every breastfeeding mother needs to take it in one form or other. Medication that is present in mothers blood will transfer into her breast milk to some extent. Most drugs do so at low levels and pose no real risk to infants but then there are some exceptions. In This post will discuss whether Morphine Sulfate Extended-release | Morphine Sulfate Tablet, Extended Release is safe in breast-feeding or not.

What is Morphine Sulfate Extended-release | Morphine Sulfate Tablet, Extended Release ?


Morphine sulfate extended-release tablets are an extended-release oral formulation of morphine sulfate indicated for the management of moderate to severe pain when a continuous, around-the-clock opioid analgesic is needed for an extended period of time. Morphine sulfate extended-release tablets are NOT intended for use as a prn analgesic. The morphine sulfate extended-release tablets 100 mg and 200 mg strengths are high dose, extended-release, oral morphine formulations indicated for the relief of pain in opioid-tolerant patients only. Morphine sulfate extended-release tablets are not indicated for pain in the immediate postoperative period (the first 12 to 24 hours following surgery) for patients not previously taking the drug, because its safety in this setting has not been established. Morphine sulfate extended-release tablets are not indicated for pain in the postoperative period if the pain is mild, or not expected to persist for an extended period of time. Morphine sulfate extended-release tablets are only indicated for postoperative use if the patient is already receiving the drug prior to surgery or if the postoperative pain is expected to be moderate to severe and persist for an extended period of time. Physicians should individualize treatment, moving from parenteral to oral analgesics as appropriate. (See American Pain Society guidelines.)

Is using Morphine Sulfate Extended-release | Morphine Sulfate Tablet, Extended Release safe or dangerous while breastfeeding?

Morphine Sulfate Extended-release | Morphine Sulfate Tablet, Extended Release low risk for breastfeeding
Morphine sulfate is the one and only active ingredient present in Morphine Sulfate Extended-release | Morphine Sulfate Tablet, Extended Release. Morphine sulfate in itself is a low risk drug for lactation so it is easy to understand that Morphine Sulfate Extended-release | Morphine Sulfate Tablet, Extended Release also comes in category of Low Risk item while breastfeeding. Below is the summary of Morphine sulfate in breastfeeding.

Statement of Manufacturer/Labeler about breastfeeding usage
Nursing Mothers Low levels of morphine have been detected in the breast milk. Withdrawal symptoms can occur in breast-feeding infants when maternal administration of morphine sulfate is stopped. Ordinarily, nursing should not be undertaken while a patient is receiving morphine sulfate extended-release tablets since morphine may be excreted in the milk.

Morphine Sulfate Extended-release | Morphine Sulfate Tablet, Extended Release Breastfeeding Analsys


Morphine sulfate while Breastfeeding

Low Risk

CAS Number: 57-27-2

Excretion into breast milk is low (even lower when administered through Epidural Anesthesia). In addition, a low oral bioavailability makes that the amount present in the infant's plasma due to absorption from milk by the gut is low. Even though, level of drug has been found in the plasma of infants from treated mothers, harmful effects in the infants were not reported. Levels in the milk are lower and side-effects are fewer among infants whose mothers were treated with Morphine than with Pethidine. Some authorities consider Morphine as the elective opioid medication for breastfeeding mothers. Analgesia used during the birth process is related to a brief delayed of stage II of Lactogenesis (milk come-in). Morphine increases Prolactin level and may decrease Oxytocin level, but it would not be determinant for already established lactations. Avoidance of repetitive or chronic use and follow-up for somnolence and adequacy of infant nourishment is recommended. Bed-sharing should be avoid whenever this medication is used by parents. The American Academy of Pediatrics rates it as compatible with breastfeeding.


Morphine Sulfate Extended-release | Morphine Sulfate Tablet, Extended Release Breastfeeding Analsys - 2


Morphine sulfate while Breastfeeding

CAS Number: 57-27-2

Is Morphine Sulfate Extended-release | Morphine Sulfate Tablet, Extended Release safe while breastfeeding

Epidural morphine given to mothers for postcesarean section analgesia results in trivial amounts of morphine in their colostrum and milk. Intravenous or oral doses of maternal morphine in the immediate postpartum period result in higher milk levels than with epidural morphine. Labor pain medication may delay the onset of lactation. Maternal use of oral narcotics during breastfeeding can cause infant drowsiness, central nervous system depression and even death, although low-dose morphine might be preferred over other opiates.[1] Newborn infants seem to be particularly sensitive to the effects of even small dosages of narcotic analgesics. Once the mother's milk comes in, it is best to provide pain control with a nonnarcotic analgesic and limit maternal intake of morphine to a 2 to 3 days at a low dosage with close infant monitoring, especially in the outpatient setting.[2] If the baby shows signs of increased sleepiness (more than usual), difficulty breastfeeding, breathing difficulties, or limpness, a physician should be contacted immediately.



I am nursing mother and I have already used Morphine Sulfate Extended-release | Morphine Sulfate Tablet, Extended Release, what should I do?

Morphine Sulfate Extended-release | Morphine Sulfate Tablet, Extended Release is in the category of low risk, if you have already used it then its not a big deal if health and behavior of baby is good. However your health care provider shall be aware of the fact that you have used Morphine Sulfate Extended-release | Morphine Sulfate Tablet, Extended Release so you should inform him based on your convenience.


My doctor has prescribed me Morphine Sulfate Extended-release | Morphine Sulfate Tablet, Extended Release, what should I do?

Though Morphine Sulfate Extended-release | Morphine Sulfate Tablet, Extended Release dose not comes in category of safe drugs rather it comes in category of low risk but if your doctor is aware that you are breastfeeding your baby and has still recommended it then its advantages must be outweighing the risks.


If I am using Morphine Sulfate Extended-release | Morphine Sulfate Tablet, Extended Release, will my baby need extra monitoring?

Not much monitoring required while using Morphine Sulfate Extended-release | Morphine Sulfate Tablet, Extended Release


Who can I talk to if I have questions about usage of Morphine Sulfate Extended-release | Morphine Sulfate Tablet, Extended Release in breastfeeding?

US
National Womens Health and Breastfeeding Helpline: 800-994-9662 (TDD 888-220-5446) 9 a.m. and 6 p.m. ET, Monday through Friday

UK
National Breastfeeding Helpline: 0300-100-0212 9.30am to 9.30pm, daily
Association of Breastfeeding Mothers: 0300-330-5453
La Leche League: 0345-120-2918
The Breastfeeding Network supporter line in Bengali and Sylheti: 0300-456-2421
National Childbirth Trust (NCT): 0300-330-0700

Australia
National Breastfeeding Helpline: 1800-686-268 24 hours a day, 7 days a week

Canada
Telehealth Ontario for breastfeeding: 1-866-797-0000 24 hours a day, 7 days a week