Infumorph 200 | Morphine Sulfate Injection Breastfeeding
There are high number of clear evidence that breastfeeding provides best nutrition that you can give to your baby. It is also evident that lactation is good for mothers health as well. Evolution has designed breastfeeding in a way that it caters all nutritional need of your child. However modern medicine is quite new for evolution, that is why mothers body is not well prepared to filter unnecessary chemical found in medicines. It becomes a necessity to figure out which drug is safe and which drug is dangerous for your newborn while nursing. In this article we will understand function of Infumorph 200 | Morphine Sulfate Injection and its suitability with breastfeeding.

What is Infumorph 200 | Morphine Sulfate Injection used for?


INFUMORPH is for use in continuous microinfusion devices and indicated only for intrathecal or epidural infusion in the management of intractable chronic pain severe enough to require an opioid analgesic and for which less invasive means of controlling pain are inadequate. Limitations of Use Not for single-dose intravenous, intramuscular, or subcutaneous administration due to the risk of overdose. Not for single-dose neuraxial injection because INFUMORPH is too concentrated for accurate delivery of the smaller doses used in this setting. INFUMORPH is an opioid agonist, for use in continuous microinfusion devices and indicated only for intrathecal or epidural infusion in the management of intractable chronic pain severe enough to require an opioid analgesic and for which alternative treatments are inadequate. (1)

I am currently breastfeeding and I want to know if using Infumorph 200 | Morphine Sulfate Injection is safe for my kid? Does it have any effect on milk production?

Infumorph 200 | Morphine Sulfate Injection low risk for breastfeeding
Morphine sulfate is the one and only active ingredient present in Infumorph 200 | Morphine Sulfate Injection. Morphine sulfate in itself is a low risk drug for lactation so it is easy to understand that Infumorph 200 | Morphine Sulfate Injection also comes in category of Low Risk item while breastfeeding. Below is the summary of Morphine sulfate in breastfeeding.

Statement of Manufacturer/Labeler about breastfeeding usage
8.3 Females and Males of Reproductive Potential Infertility Chronic use of opioids may cause reduced fertility in females and males of reproductive potential. It is not known whether these effects on fertility are reversible [see Adverse Reactions (6), Clinical Pharmacology (12.2)]. In published animal studies, morphine administration adversely effected fertility and reproductive endpoints in male rats and prolonged estrus cycle in female rats [see Nonclinical Toxicology (13)].

Infumorph 200 | Morphine Sulfate Injection Breastfeeding Analsys


Morphine sulfate while Breastfeeding

Low Risk

CAS Number: 57-27-2

Excretion into breast milk is low (even lower when administered through Epidural Anesthesia). In addition, a low oral bioavailability makes that the amount present in the infant's plasma due to absorption from milk by the gut is low. Even though, level of drug has been found in the plasma of infants from treated mothers, harmful effects in the infants were not reported. Levels in the milk are lower and side-effects are fewer among infants whose mothers were treated with Morphine than with Pethidine. Some authorities consider Morphine as the elective opioid medication for breastfeeding mothers. Analgesia used during the birth process is related to a brief delayed of stage II of Lactogenesis (milk come-in). Morphine increases Prolactin level and may decrease Oxytocin level, but it would not be determinant for already established lactations. Avoidance of repetitive or chronic use and follow-up for somnolence and adequacy of infant nourishment is recommended. Bed-sharing should be avoid whenever this medication is used by parents. The American Academy of Pediatrics rates it as compatible with breastfeeding.


Infumorph 200 | Morphine Sulfate Injection Breastfeeding Analsys - 2


Morphine sulfate while Breastfeeding

CAS Number: 57-27-2

Is Infumorph 200 | Morphine Sulfate Injection safe while breastfeeding

Epidural morphine given to mothers for postcesarean section analgesia results in trivial amounts of morphine in their colostrum and milk. Intravenous or oral doses of maternal morphine in the immediate postpartum period result in higher milk levels than with epidural morphine. Labor pain medication may delay the onset of lactation. Maternal use of oral narcotics during breastfeeding can cause infant drowsiness, central nervous system depression and even death, although low-dose morphine might be preferred over other opiates.[1] Newborn infants seem to be particularly sensitive to the effects of even small dosages of narcotic analgesics. Once the mother's milk comes in, it is best to provide pain control with a nonnarcotic analgesic and limit maternal intake of morphine to a 2 to 3 days at a low dosage with close infant monitoring, especially in the outpatient setting.[2] If the baby shows signs of increased sleepiness (more than usual), difficulty breastfeeding, breathing difficulties, or limpness, a physician should be contacted immediately.


Infumorph 200 | Morphine Sulfate Injection safe for breastfeeding

What should I do if I am breastfeeding mother and I am already exposed to Infumorph 200 | Morphine Sulfate Injection?

Infumorph 200 | Morphine Sulfate Injection is in the category of low risk, if you have already used it then its not a big deal if health and behavior of baby is good. However your health care provider shall be aware of the fact that you have used Infumorph 200 | Morphine Sulfate Injection so you should inform him based on your convenience.


My health care provider has asked me to use Infumorph 200 | Morphine Sulfate Injection, what to do?

Infumorph 200 | Morphine Sulfate Injection comes in category of low risk and if your doctor is aware that you are breastfeeding it should be ok to use without much concerns.


If I am using Infumorph 200 | Morphine Sulfate Injection, will my baby need extra monitoring?

Not much monitoring required while using Infumorph 200 | Morphine Sulfate Injection


Who can I talk to if I have questions about usage of Infumorph 200 | Morphine Sulfate Injection in breastfeeding?

US
National Womens Health and Breastfeeding Helpline: 800-994-9662 (TDD 888-220-5446) 9 a.m. and 6 p.m. ET, Monday through Friday

UK
National Breastfeeding Helpline: 0300-100-0212 9.30am to 9.30pm, daily
Association of Breastfeeding Mothers: 0300-330-5453
La Leche League: 0345-120-2918
The Breastfeeding Network supporter line in Bengali and Sylheti: 0300-456-2421
National Childbirth Trust (NCT): 0300-330-0700

Australia
National Breastfeeding Helpline: 1800-686-268 24 hours a day, 7 days a week

Canada
Telehealth Ontario for breastfeeding: 1-866-797-0000 24 hours a day, 7 days a week