Dorzolamide Hydrochloride-timolol Maleate Solution while Breastfeeding
It is a well known fact that breastfeeding is best source of nutrition for infants. Breast milk provides minerals, vitamins and antibodies in most acceptable format when they need it. Nutrition taken by mother passes to breast-milk and same thing applies to medicines taken by mothers. Not all drugs cause problem for baby but some do. Lets analyze if Dorzolamide Hydrochloride-timolol Maleate Solution is safe for baby while breastfed.

What is Dorzolamide Hydrochloride-timolol Maleate Solution used for?


​INDICATIONS AND USAGE Dorzolamide hydrochloride-timolol maleate ophthalmic solution is indicated for the reduction of elevated intraocular pressure in patients with open-angle glaucoma or ocular hypertension who are insufficiently responsive to beta-blockers (failed to achieve target IOP determined after multiple measurements over time). The IOP-lowering of dorzolamide hydrochloride-timolol maleate ophthalmic solution b.i.d. was slightly less than that seen with the concomitant administration of 0.5% timolol b.i.d. and 2.0% dorzolamide t.i.d. (see CLINICAL PHARMACOLOGY, Clinical Studies ).

Is using Dorzolamide Hydrochloride-timolol Maleate Solution unsafe in breastfeeding? Can there be bad consequences for baby if I use it while breastfeeding?

Dorzolamide Hydrochloride-timolol Maleate Solution low risk for breastfeeding
Dorzolamide and Timolol anhydrous are the two main ingredients of Dorzolamide Hydrochloride-timolol Maleate Solution. Based on our individual analysis of Dorzolamide and Timolol anhydrous we can safely say that Dorzolamide Hydrochloride-timolol Maleate Solution has low risk while breastfeeding. Below we have summarized the usage of Dorzolamide and Timolol anhydrous while breastfeeding, we recommend you to go through it for better understanding of your usage.

Statement of Manufacturer/Labeler about breastfeeding usage
Nursing Mothers It is not known whether dorzolamide is excreted in human milk. Timolol maleate has been detected in human milk following oral and ophthalmic drug administration. Because of the potential for serious adverse reactions from dorzolamide hydrochloride-timolol maleate ophthalmic solution in nursing infants, a decision should be made whether to discontinue nursing or to discontinue the drug, taking into account the importance of the drug to the mother.

Dorzolamide Hydrochloride-timolol Maleate Solution Breastfeeding Analsys


Dorzolamide while Breastfeeding

Low Risk

It inhibits activity of carbonic anhydrase.Systemic absorption is minimal. There have not been problems except when a maternal overdose was absorbed. Like most ophthalmologic compounds for topical use a low dose and poor absorption make it compatible with breastfeeding. No untoward effect has been described.

Timolol anhydrous while Breastfeeding

Safe

CAS Number: 26839-75-8

It is used as hypotensive drug, and, on topical treatment of glaucoma. Systemic absorption is minimal. There have not been problems except when a maternal overdose has been absorbed. Like most ophthalmologic compounds for topical use a low dose and poor absorption make it compatible with breastfeeding.


Dorzolamide Hydrochloride-timolol Maleate Solution Breastfeeding Analsys - 2


Dorzolamide while Breastfeeding

CAS Number: 120279-96-1

Limited experience with the use of ophthalmic dorzolamide indicate that it is unlikely to adversely affect the breastfed infant. To substantially diminish the amount of drug that reaches the breastmilk after using eye drops, place pressure over the tear duct by the corner of the eye for 1 minute or more, then remove the excess solution with an absorbent tissue.

Timolol anhydrous while Breastfeeding

CAS Number: 26839-75-8

Because of the variability in excretion of timolol into breastmilk and minimal reported experience during breastfeeding, other agents may be preferred, especially while nursing a newborn or preterm infant.Ophthalmic use of timolol by the mother should pose little risk to the breastfed infant. To substantially diminish the amount of drug that reaches the breastmilk after using eye drops, place pressure over the tear duct by the corner of the eye for 1 minute or more, then remove the excess solution with an absorbent tissue.



What should I do if already breastfed my kid after using Dorzolamide Hydrochloride-timolol Maleate Solution?

Dorzolamide Hydrochloride-timolol Maleate Solution is in the category of low risk, if you have already used it then its not a big deal if health and behavior of baby is good. However your health care provider shall be aware of the fact that you have used Dorzolamide Hydrochloride-timolol Maleate Solution so you should inform him based on your convenience.


My health care provider has asked me to use Dorzolamide Hydrochloride-timolol Maleate Solution, what to do?

Though Dorzolamide Hydrochloride-timolol Maleate Solution dose not comes in category of safe drugs rather it comes in category of low risk but if your doctor is aware that you are breastfeeding your baby and has still recommended it then its advantages must be outweighing the risks.


If I am using Dorzolamide Hydrochloride-timolol Maleate Solution, will my baby need extra monitoring?

Not much monitoring required while using Dorzolamide Hydrochloride-timolol Maleate Solution


Who can I talk to if I have questions about usage of Dorzolamide Hydrochloride-timolol Maleate Solution in breastfeeding?

US
National Womens Health and Breastfeeding Helpline: 800-994-9662 (TDD 888-220-5446) 9 a.m. and 6 p.m. ET, Monday through Friday

UK
National Breastfeeding Helpline: 0300-100-0212 9.30am to 9.30pm, daily
Association of Breastfeeding Mothers: 0300-330-5453
La Leche League: 0345-120-2918
The Breastfeeding Network supporter line in Bengali and Sylheti: 0300-456-2421
National Childbirth Trust (NCT): 0300-330-0700

Australia
National Breastfeeding Helpline: 1800-686-268 24 hours a day, 7 days a week

Canada
Telehealth Ontario for breastfeeding: 1-866-797-0000 24 hours a day, 7 days a week

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