There are high number of clear evidence that breastfeeding provides best nutrition that you can give to your baby. It is also evident that lactation is good for mothers health as well. Evolution has designed breastfeeding in a way that it caters all nutritional need of your child. However modern medicine is quite new for evolution, that is why mothers body is not well prepared to filter unnecessary chemical found in medicines. It becomes a necessity to figure out which drug is safe and which drug is dangerous for your newborn while nursing. In this article we will understand function of Dorzolamide Hydrochloride And Timolol Maleate Preservative Free Solution/ Drops and its suitability with breastfeeding.
What is Dorzolamide Hydrochloride And Timolol Maleate Preservative Free Solution/ Drops ?
Dorzolamide hydrochloride and timolol maleate ophthalmic solution preservative free is indicated for the reduction of elevated intraocular pressure (IOP) in patients with open-angle glaucoma or ocular hypertension who are insufficiently responsive to beta-blockers (failed to achieve target IOP determined after multiple measurements over time). The IOP-lowering of dorzolamide hydrochloride and timolol maleate ophthalmic solution administered twice a day was slightly less than that seen with the concomitant administration of 0.5% timolol administered twice a day and 2% dorzolamide administered three times a day [see Clinical Studies (14.1)]. Dorzolamide hydrochloride and timolol maleate ophthalmic solution preservative free is a carbonic anhydrase inhibitor with a beta-adrenergic receptor blocking agent indicated for the reduction of elevated intraocular pressure (IOP) in patients with open-angle glaucoma or ocular hypertension who are insufficiently responsive to beta-blockers. The IOP-lowering of dorzolamide hydrochloride and timolol maleate ophthalmic solution twice daily was slightly less than that seen with the concomitant administration of 0.5% timolol twice daily, and 2% dorzolamide three times daily. (1)
Can I use Dorzolamide Hydrochloride And Timolol Maleate Preservative Free Solution/ Drops while breastfeeding?
Dorzolamide and Timolol anhydrous are the two main ingredients of Dorzolamide Hydrochloride And Timolol Maleate Preservative Free Solution/ Drops. Based on our individual analysis of Dorzolamide and Timolol anhydrous we can safely say that Dorzolamide Hydrochloride And Timolol Maleate Preservative Free Solution/ Drops has low risk while breastfeeding. Below we have summarized the usage of Dorzolamide and Timolol anhydrous while breastfeeding, we recommend you to go through it for better understanding of your usage.
Statement of Manufacturer/Labeler about breastfeeding usage
8.3 Nursing Mothers It is not known whether dorzolamide is excreted in human milk. Timolol maleate has been detected in human milk following oral and ophthalmic drug administration. Because of the potential for serious adverse reactions from dorzolamide hydrochloride and timolol maleate ophthalmic solution preservative free in nursing infants, a decision should be made whether to discontinue nursing or to discontinue the drug, taking into account the importance of the drug to the mother.
Dorzolamide Hydrochloride And Timolol Maleate Preservative Free Solution/ Drops Breastfeeding Analsys
Low RiskIt inhibits activity of carbonic anhydrase.Systemic absorption is minimal. There have not been problems except when a maternal overdose was absorbed. Like most ophthalmologic compounds for topical use a low dose and poor absorption make it compatible with breastfeeding. No untoward effect has been described.
SafeCAS Number: 26839-75-8
It is used as hypotensive drug, and, on topical treatment of glaucoma. Systemic absorption is minimal. There have not been problems except when a maternal overdose has been absorbed. Like most ophthalmologic compounds for topical use a low dose and poor absorption make it compatible with breastfeeding.
Dorzolamide Hydrochloride And Timolol Maleate Preservative Free Solution/ Drops Breastfeeding Analsys - 2
CAS Number: 120279-96-1
Limited experience with the use of ophthalmic dorzolamide indicate that it is unlikely to adversely affect the breastfed infant. To substantially diminish the amount of drug that reaches the breastmilk after using eye drops, place pressure over the tear duct by the corner of the eye for 1 minute or more, then remove the excess solution with an absorbent tissue.
CAS Number: 26839-75-8

Because of the variability in excretion of timolol into breastmilk and minimal reported experience during breastfeeding, other agents may be preferred, especially while nursing a newborn or preterm infant.Ophthalmic use of timolol by the mother should pose little risk to the breastfed infant. To substantially diminish the amount of drug that reaches the breastmilk after using eye drops, place pressure over the tear duct by the corner of the eye for 1 minute or more, then remove the excess solution with an absorbent tissue.

What should I do if I am breastfeeding mother and I am already exposed to Dorzolamide Hydrochloride And Timolol Maleate Preservative Free Solution/ Drops?
Dorzolamide Hydrochloride And Timolol Maleate Preservative Free Solution/ Drops is in the category of low risk, if you have already used it then its not a big deal if health and behavior of baby is good. However your health care provider shall be aware of the fact that you have used Dorzolamide Hydrochloride And Timolol Maleate Preservative Free Solution/ Drops so you should inform him based on your convenience.
My doctor has prescribed me Dorzolamide Hydrochloride And Timolol Maleate Preservative Free Solution/ Drops, what should I do?
Dorzolamide Hydrochloride And Timolol Maleate Preservative Free Solution/ Drops comes in category of low risk and if your doctor is aware that you are breastfeeding it should be ok to use without much concerns.
If I am using Dorzolamide Hydrochloride And Timolol Maleate Preservative Free Solution/ Drops, will my baby need extra monitoring?
Not much monitoring required while using Dorzolamide Hydrochloride And Timolol Maleate Preservative Free Solution/ Drops
Who can I talk to if I have questions about usage of Dorzolamide Hydrochloride And Timolol Maleate Preservative Free Solution/ Drops in breastfeeding?
US
National Womens Health and Breastfeeding Helpline: 800-994-9662 (TDD 888-220-5446) 9 a.m. and 6 p.m. ET, Monday through Friday
UK
National Breastfeeding Helpline: 0300-100-0212 9.30am to 9.30pm, daily
Association of Breastfeeding Mothers: 0300-330-5453
La Leche League: 0345-120-2918
The Breastfeeding Network supporter line in Bengali and Sylheti: 0300-456-2421
National Childbirth Trust (NCT): 0300-330-0700
Australia
National Breastfeeding Helpline: 1800-686-268 24 hours a day, 7 days a week
Canada
Telehealth Ontario for breastfeeding: 1-866-797-0000 24 hours a day, 7 days a week
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