Hyperhep B | Hepatitis B Immune Globulin (human) Injection Breastfeeding

There are high number of clear evidence that breastfeeding provides best nutrition that you can give to your baby. It is also evident that lactation is good for mothers health as well. Evolution has designed breastfeeding in a way that it caters all nutritional need of your child. However modern medicine is quite new for evolution, that is why mothers body is not well prepared to filter unnecessary chemical found in medicines. It becomes a necessity to figure out which drug is safe and which drug is dangerous for your newborn while nursing. In this article we will understand function of Hyperhep B | Hepatitis B Immune Globulin (human) Injection and its suitability with breastfeeding.

What is Hyperhep B | Hepatitis B Immune Globulin (human) Injection used for?


Recommendations on post-exposure prophylaxis are based on available efficacy data and on the likelihood of future HBV exposure for the person requiring treatment. In all exposures, a regimen combining Hepatitis B Immune Globulin (Human) with hepatitis B vaccine will provide both short- and long-term protection, will be less costly than the two-dose Hepatitis B Immune Globulin (Human) treatment alone, and is the treatment of choice.(8) HyperHEP B S/D is indicated for post-exposure prophylaxis in the following situations: Acute Exposure to Blood Containing HBsAg After either parenteral exposure, e.g., by accidental “needlestick” or direct mucous membrane contact (accidental splash), or oral ingestion (pipetting accident) involving HBsAg-positive materials such as blood, plasma or serum. For inadvertent percutaneous exposure, a regimen of two doses of Hepatitis B Immune Globulin (Human), one given after exposure and one a month later, is about 75% effective in preventing hepatitis B in this setting. Perinatal Exposure of Infants Born to HBsAg-positive Mothers Infants born to HBsAg-positive mothers are at risk of being infected with hepatitis B virus and becoming chronic carriers.(5,8-10) This risk is especially great if the mother is HBeAg-positive.(11-13) For an infant with perinatal exposure to an HBsAg-positive and HBeAg-positive mother, a regimen combining one dose of Hepatitis B Immune Globulin (Human) at birth with the hepatitis B vaccine series started soon after birth is 85%–95% effective in preventing development of the HBV carrier state.(8,14) Regimens involving either multiple doses of Hepatitis B Immune Globulin (Human) alone or the vaccine series alone have 70%–90% efficacy, while a single dose of Hepatitis B Immune Globulin (Human) alone has only 50% efficacy.(8,15) Sexual Exposure to an HBsAg-positive Person Sex partners of HBsAg-positive persons are at increased risk of acquiring HBV infection. For sexual exposure to a person with acute hepatitis B, a single dose of Hepatitis B Immune Globulin (Human) is 75% effective if administered within 2 weeks of last sexual exposure.(8) Household Exposure to Persons with Acute HBV Infection Since infants have close contact with primary care-givers and they have a higher risk of becoming HBV carriers after acute HBV infection, prophylaxis of an infant less than 12 months of age with Hepatitis B Immune Globulin (Human) and hepatitis B vaccine is indicated if the mother or primary care-giver has acute HBV infection.(8) Administration of Hepatitis B Immune Globulin (Human) either preceding or concomitant with the commencement of active immunization with Hepatitis B Vaccine provides for more rapid achievement of protective levels of hepatitis B antibody, than when the vaccine alone is administered.(16) Rapid achievement of protective levels of antibody to hepatitis B virus may be desirable in certain clinical situations, as in cases of accidental inoculations with contaminated medical instruments.(16) Administration of Hepatitis B Immune Globulin (Human) either 1 month preceding or at the time of commencement of a program of active vaccination with Hepatitis B Vaccine has been shown not to interfere with the active immune response to the vaccine.(16)

Is Hyperhep B | Hepatitis B Immune Globulin (human) Injection safe to use while breastfeeding? Can it interfere with growth and development of my kid?

Hyperhep B | Hepatitis B Immune Globulin (human) Injection safe for breastfeeding
Active ingredient in Hyperhep B | Hepatitis B Immune Globulin (human) Injection is Human hepatitis b virus immune globulin and based on our analysis of Human hepatitis b virus immune globulin it appears that using Hyperhep B | Hepatitis B Immune Globulin (human) Injection is safe in breastfeeding. Below is analysis of Human hepatitis b virus immune globulin while breastfeeding.

Hyperhep B | Hepatitis B Immune Globulin (human) Injection Breastfeeding Analsys


Human hepatitis b virus immune globulin while Breastfeeding

Safe

The secretion of immunoglobulin into breast milk may help to transfer passive immunitation to the child.


Hyperhep B | Hepatitis B Immune Globulin (human) Injection Breastfeeding Analsys - 2


Human hepatitis b virus immune globulin while Breastfeeding

CAS Number: 373609-41-7

Hyperhep B | Hepatitis B Immune Globulin (human) Injection and breastfeeding

Hepatitis B immune globulin is an immune globulin (IgG) rich in IgG antibodies against hepatis B. IgG is a normal component of breastmilk. No special precautions are required during breastfeeding. Hepatitis B immune globulin is recommended along with hepatitis B vaccine to be given to infants of mothers who are positive for hepatitis B surface antigen. No differences exist in infection rates between breast-fed and formula-fed infants born to hepatitis B-infected women, as long as the infant receives these preventative measures at birth. Mothers with hepatitis B are encouraged to breastfeed their infants after their infants receive these preventative measures.[1][2] Holder pasteurization (62.5 degrees C for 30 minutes) decreases the concentration of endogenous immunoglobulin G by up to 79%.[3][4] Higher temperatures of 72 and 85 degrees C appear to cause greater loss, but further lyophylization does not cause marked additional loss.[5] A flash heating pasteurization reduced the concentration of endogenous immunoglobulin G by 33%.[6] A continuous flow, high-temperature short-time (HTST) pasteurizer at temperatures ranging from 71 to 74 degrees C retained from about 38 to 79% of IgG activity depending on the temperature and exposure time.[7] A study of 67 colostrum samples that underwent Holder pasteurization found that IgG amounts decreased by 34 to 40%. Immunoreactivity against ovalbumin decreased by 4 to 18% and immunoreactivity against tetanus toxoid decreased by 8 to 20%. Specific IgG subclasses decreased by different amounts, with IgG4 retaining all of its activity and IgG1 and 2 decreasing by about 40 to 50%.[8]


Is Hyperhep B | Hepatitis B Immune Globulin (human) Injection safe while breastfeeding

What should I do if I am breastfeeding mother and I am already exposed to Hyperhep B | Hepatitis B Immune Globulin (human) Injection?

It is always a good idea to keep your healthcare provider or doctor informed about your drug usage during pregnancy and breastfeeding but if you have not informed your doctor about Hyperhep B | Hepatitis B Immune Globulin (human) Injection and have used it then do not panic as Hyperhep B | Hepatitis B Immune Globulin (human) Injection is mostly safe in breastfeeding and should not cause any harm to your baby.


My health care provider has asked me to use Hyperhep B | Hepatitis B Immune Globulin (human) Injection, what to do?

Usage of Hyperhep B | Hepatitis B Immune Globulin (human) Injection is safe for nursing mothers and baby, No worries.


If I am using Hyperhep B | Hepatitis B Immune Globulin (human) Injection, will my baby need extra monitoring?

No


Who can I talk to if I have questions about usage of Hyperhep B | Hepatitis B Immune Globulin (human) Injection in breastfeeding?

US
National Womens Health and Breastfeeding Helpline: 800-994-9662 (TDD 888-220-5446) 9 a.m. and 6 p.m. ET, Monday through Friday

UK
National Breastfeeding Helpline: 0300-100-0212 9.30am to 9.30pm, daily
Association of Breastfeeding Mothers: 0300-330-5453
La Leche League: 0345-120-2918
The Breastfeeding Network supporter line in Bengali and Sylheti: 0300-456-2421
National Childbirth Trust (NCT): 0300-330-0700

Australia
National Breastfeeding Helpline: 1800-686-268 24 hours a day, 7 days a week

Canada
Telehealth Ontario for breastfeeding: 1-866-797-0000 24 hours a day, 7 days a week