Nabi-hb | Human Hepatitis B Virus Immune Globulin Injection while Breastfeeding
It is recommended to breastfeed exclusively for six months and then while introducing to other food sources extend it to twelve months. In this duration most mothers will need help of some sort of medication, It could be for short term like could and flue or it could be something chronic like Arthritis or Diabetes and here comes the question of safety of medication in use. In this post we will figure out what is Nabi-hb | Human Hepatitis B Virus Immune Globulin Injection and whether its safe to use Nabi-hb | Human Hepatitis B Virus Immune Globulin Injection while nursing or not.

What is Nabi-hb | Human Hepatitis B Virus Immune Globulin Injection used for?


Nabi-HB, Hepatitis B Immune Globulin (Human), is indicated for treatment of acute exposure to blood containing HBsAg, perinatal exposure of infants born to HBsAg-positive mothers, sexual exposure to HBsAg-positive persons and household exposure to persons with acute HBV infection in the following settings: Acute Exposure to Blood Containing HBsAg Following either parenteral exposure (needlestick, bite, sharps), direct mucous membrane contact (accidental splash), or oral ingestion (pipetting accident), involving HBsAg-positive materials such as blood, plasma, or serum. Perinatal Exposure of Infants Born to HBsAg-positive Mothers Infants born to mothers positive for HBsAg with or without HBeAg12. Sexual Exposure to HBsAg-positive Persons Sexual partners of HBsAg-positive persons. Household Exposure to Persons with Acute HBV Infection Infants less than 12 months old whose mother or primary caregiver is positive for HBsAg. Other household contacts with an identifiable blood exposure to the index patient. Nabi-HB is indicated for intramuscular use only.

Can I continue breastfeeding if I am using Nabi-hb | Human Hepatitis B Virus Immune Globulin Injection? How long does it stays in breast milk?

Nabi-hb | Human Hepatitis B Virus Immune Globulin Injection safe for breastfeeding
As per our analysis Nabi-hb | Human Hepatitis B Virus Immune Globulin Injection contains only one ingredient and that is Human hepatitis b virus immune globulin. We have analyzed Human hepatitis b virus immune globulin and it seems to be safe to use Human hepatitis b virus immune globulin while breastfeeding, that means usage of Nabi-hb | Human Hepatitis B Virus Immune Globulin Injection shall be safe while breastfeeding. Below you can check more details of Human hepatitis b virus immune globulin usage in breastfeeding. We recommend you to go through provided detailed analysis as below take decision accordingly.

Statement of Manufacturer/Labeler about breastfeeding usage
Nursing Mothers It is not known whether this drug is excreted in human milk. Because many drugs are excreted in human milk, caution should be exercised when Nabi-HB is administered to a nursing mother.

Nabi-hb | Human Hepatitis B Virus Immune Globulin Injection Breastfeeding Analsys


Human hepatitis b virus immune globulin while Breastfeeding

Safe

The secretion of immunoglobulin into breast milk may help to transfer passive immunitation to the child.

Nabi-hb | Human Hepatitis B Virus Immune Globulin Injection Breastfeeding Analsys - 2


Human hepatitis b virus immune globulin while Breastfeeding

CAS Number: 373609-41-7

Hepatitis B immune globulin is an immune globulin (IgG) rich in IgG antibodies against hepatis B. IgG is a normal component of breastmilk. No special precautions are required during breastfeeding. Hepatitis B immune globulin is recommended along with hepatitis B vaccine to be given to infants of mothers who are positive for hepatitis B surface antigen. No differences exist in infection rates between breast-fed and formula-fed infants born to hepatitis B-infected women, as long as the infant receives these preventative measures at birth. Mothers with hepatitis B are encouraged to breastfeed their infants after their infants receive these preventative measures.[1][2] Holder pasteurization (62.5 degrees C for 30 minutes) decreases the concentration of endogenous immunoglobulin G by up to 79%.[3][4] Higher temperatures of 72 and 85 degrees C appear to cause greater loss, but further lyophylization does not cause marked additional loss.[5] A flash heating pasteurization reduced the concentration of endogenous immunoglobulin G by 33%.[6] A continuous flow, high-temperature short-time (HTST) pasteurizer at temperatures ranging from 71 to 74 degrees C retained from about 38 to 79% of IgG activity depending on the temperature and exposure time.[7] A study of 67 colostrum samples that underwent Holder pasteurization found that IgG amounts decreased by 34 to 40%. Immunoreactivity against ovalbumin decreased by 4 to 18% and immunoreactivity against tetanus toxoid decreased by 8 to 20%. Specific IgG subclasses decreased by different amounts, with IgG4 retaining all of its activity and IgG1 and 2 decreasing by about 40 to 50%.[8]


What if I already have used Nabi-hb | Human Hepatitis B Virus Immune Globulin Injection?

As usage of Nabi-hb | Human Hepatitis B Virus Immune Globulin Injection is mostly safe while breastfeeding hence there should not be any concern. In case of any change in behavior or health of your baby you should inform your health care provider about usage of Nabi-hb | Human Hepatitis B Virus Immune Globulin Injection else no further action is required.


My health care provider has asked me to use Nabi-hb | Human Hepatitis B Virus Immune Globulin Injection, what to do?

Usage of Nabi-hb | Human Hepatitis B Virus Immune Globulin Injection is safe for nursing mothers and baby, No worries.


If I am using Nabi-hb | Human Hepatitis B Virus Immune Globulin Injection, will my baby need extra monitoring?

No


Who can I talk to if I have questions about usage of Nabi-hb | Human Hepatitis B Virus Immune Globulin Injection in breastfeeding?

US
National Womens Health and Breastfeeding Helpline: 800-994-9662 (TDD 888-220-5446) 9 a.m. and 6 p.m. ET, Monday through Friday

UK
National Breastfeeding Helpline: 0300-100-0212 9.30am to 9.30pm, daily
Association of Breastfeeding Mothers: 0300-330-5453
La Leche League: 0345-120-2918
The Breastfeeding Network supporter line in Bengali and Sylheti: 0300-456-2421
National Childbirth Trust (NCT): 0300-330-0700

Australia
National Breastfeeding Helpline: 1800-686-268 24 hours a day, 7 days a week

Canada
Telehealth Ontario for breastfeeding: 1-866-797-0000 24 hours a day, 7 days a week