Apriso | Mesalamine Capsule, Extended Release while Breastfeeding
What is Apriso | Mesalamine Capsule, Extended Release used for?
I am currently breastfeeding and I want to know if using Apriso | Mesalamine Capsule, Extended Release is safe for my kid? Does it have any effect on milk production?
8.3 Nursing Mothers Low concentrations of mesalamine and higher concentrations of its N-acetyl metabolite have been detected in human breast milk. The clinical significance of this has not been determined and there is limited experience of nursing women using mesalamine. Caution should be exercised when APRISO is administered to a nursing woman.
Apriso | Mesalamine Capsule, Extended Release Breastfeeding Analsys
Mesalamine while Breastfeeding
SafeCAS Number: 89-57-6
Mesalazine is badly absorbed by the intestine, serum levels are low with scant excretion into breast milk. N-acetyl-5-ASA is an inactive metabolite which is excreted into breast milk but not higher than 10% of relative infant's dose. No harm effects among breastfed infants from treated mothers have been reported, except for rare cases of diarrhea reported in the 80's with the use of Mesalazine compounds different to Balsalazide. In a review of 121 cases and 121 controls, the authors failed to observe those findings. (Moretti, 1989). Expert consensus supports the compatibility of Mesalazine during breastfeeding.
Apriso | Mesalamine Capsule, Extended Release Breastfeeding Analsys - 2
Mesalamine while Breastfeeding
CAS Number: 89-57-6
Mesalamine is poorly excreted into breastmilk. However, rather high levels of the mesalamine metabolite N-acetyl-5-ASA appear in breastmilk and its effects on breastfed infants are unknown. A few cases of diarrhea have been reported in infants exposed to mesalamine, although the rate is not high. Most experts consider mesalamine derivatives to be safe during breastfeeding.[1][2][3][4] If mesalamine is required by the mother, it is not a reason to discontinue breastfeeding, but carefully observe breastfed infants for diarrhea during maternal use of mesalamine.
I already used Apriso | Mesalamine Capsule, Extended Release and meanwhile I breastfed my baby should I be concerned?
Apriso | Mesalamine Capsule, Extended Release is safe in breastfeeding and should not create any health problem for your baby but in case you feel any health issue associated with Apriso | Mesalamine Capsule, Extended Release you should contact your doctor or health care provider. Be it pregnancy or lactation you shall keep your doctor informed.
My health care provider has asked me to use Apriso | Mesalamine Capsule, Extended Release, what to do?
Usage of Apriso | Mesalamine Capsule, Extended Release is safe for nursing mothers and baby, No worries.
If I am using Apriso | Mesalamine Capsule, Extended Release, will my baby need extra monitoring?
No
Who can I talk to if I have questions about usage of Apriso | Mesalamine Capsule, Extended Release in breastfeeding?
US
National Womens Health and Breastfeeding Helpline: 800-994-9662 (TDD 888-220-5446) 9 a.m. and 6 p.m. ET, Monday through Friday
UK
National Breastfeeding Helpline: 0300-100-0212 9.30am to 9.30pm, daily
Association of Breastfeeding Mothers: 0300-330-5453
La Leche League: 0345-120-2918
The Breastfeeding Network supporter line in Bengali and Sylheti: 0300-456-2421
National Childbirth Trust (NCT): 0300-330-0700
Australia
National Breastfeeding Helpline: 1800-686-268 24 hours a day, 7 days a week
Canada
Telehealth Ontario for breastfeeding: 1-866-797-0000 24 hours a day, 7 days a week