Voriconazole Injection, Powder, For Solution while Breastfeeding

Modern medicine has evolved so much so that sooner or later every breastfeeding mother needs to take it in one form or other. Medication that is present in mothers blood will transfer into her breast milk to some extent. Most drugs do so at low levels and pose no real risk to infants but then there are some exceptions. In This post will discuss whether Voriconazole Injection, Powder, For Solution is safe in breast-feeding or not.

Voriconazole for Injection is indicated for use in patients 12 years of age and older in the treatment of the following fungal infections: Voriconazole for Injection is an azole antifungal indicated for use in the treatment of: Invasive aspergillosis (1.1) Candidemia (nonneutropenics) and disseminated candidiasis in skin, abdomen, kidney, bladder wall, and wounds (1.2) Esophageal candidiasis (1.3) Serious infections caused by Scedosporium apiospermum and Fusarium species including Fusarium solani , in patients intolerant of, or refractory to, other therapy (1.4) 1.1 Invasive Aspergillosis In clinical trials, the majority of isolates recovered were Aspergillus fumigatus . There was a small number of cases of culture-proven disease due to species of Aspergillus other than A. fumigatus [ see Clinical Studies (14.1), and Clinical Pharmacology (12.4) ]. 1.2 Candidemia in Non-neutropenic Patients and the Following Candida Infections: Disseminated Infections in Skin and Infections in Abdomen, Kidney, Bladder Wall, and Wounds [ see Clinical Studies (14.2), and Clinical Pharmacology (12.4) ] 1.3 Esophageal Candidiasis [ see Clinical Studies (14.3), and Clinical Pharmacology (12.4) ] 1.4 Serious Fungal Infections Caused by Scedosporium apiospermum (Asexual Form of Pseudallescheria boydii) and Fusarium spp, Including Fusarium solani, in Patients Intolerant of, or Refractory to, Other Therapy [ see Clinical Studies (14.4), and Clinical Pharmacology (12.4) ] Specimens for fungal culture and other relevant laboratory studies (including histopathology) should be obtained prior to therapy to isolate and identify causative organism(s). Therapy may be instituted before the results of the cultures and other laboratory studies are known. However, once these results become available, antifungal therapy should be adjusted accordingly.