There are high number of clear evidence that breastfeeding provides best nutrition that you can give to your baby. It is also evident that lactation is good for mothers health as well. Evolution has designed breastfeeding in a way that it caters all nutritional need of your child. However modern medicine is quite new for evolution, that is why mothers body is not well prepared to filter unnecessary chemical found in medicines. It becomes a necessity to figure out which drug is safe and which drug is dangerous for your newborn while nursing. In this article we will understand function of Voriconazole Suspension and its suitability with breastfeeding.
What is Voriconazole Suspension used for?
Voriconazole is an azole antifungal drug indicated for use in the treatment of: Invasive aspergillosis (1.1) Candidemia (nonneutropenics) and disseminated candidiasis in skin, abdomen, kidney, bladder wall and wounds (1.2) Esophageal candidiasis (1.3) Serious infections caused by Scedosporium apiospermum and Fusarium species including Fusarium solani , in patients intolerant of, or refractory to, other therapy (1.4) Voriconazole is indicated for use in patients 12 years of age and older in the treatment of the following fungal infections: 1.1 Invasive Aspergillosis In clinical trials, the majority of isolates recovered were Aspergillus fumigatus. There was a small number of cases of culture-proven disease due to species of Aspergillus other than A. fumigatus [see Clinical Studies (14.1) and Clinical Pharmacology (12.4)]. 1.2 Candidemia in Non-neutropenic Patients and the Following Candida Infections: Disseminated Infections in Skin and Infections in Abdomen, Kidney, Bladder Wall, and Wounds [See Clinical Studies (14.2) and Clinical Pharmacology (12.4).] 1.3 Esophageal Candidiasis [See Clinical Studies (14.3) and Clinical Pharmacology (12.4).] 1.4 Serious Fungal Infections Caused by Scedosporium apiospermum (Asexual Form of Pseudallescheria boydii) and Fusarium spp. Including Fusarium solani, in Patients Intolerant of, or Refractory to, Other Therapy [See Clinical Studies (14.4) and Clinical Pharmacology (12.4).] Specimens for fungal culture and other relevant laboratory studies (including histopathology) should be obtained prior to therapy to isolate and identify causative organism(s). Therapy may be instituted before the results of the cultures and other laboratory studies are known. However, once these results become available, antifungal therapy should be adjusted accordingly.
Is Voriconazole Suspension usage safe while breastfeeding? If a lactating mother is using it can there be any effect on growth or development of infant?
Voriconazole is the one and only active ingredient present in Voriconazole Suspension. Voriconazole in itself is a low risk drug for lactation so it is easy to understand that Voriconazole Suspension also comes in category of Low Risk item while breastfeeding. Below is the summary of Voriconazole in breastfeeding.
Statement of Manufacturer/Labeler about breastfeeding usage
8.3 Nursing Mothers It is not known whether voriconazole is excreted in human milk. Because many drugs are excreted in human milk and because of the potential for serious adverse reactions in nursing infants from voriconazole, a decision should be made whether to discontinue nursing or discontinue the drug, taking into account the importance of the drug to the mother.
Voriconazole Suspension Breastfeeding Analsys
Low RiskCAS Number: 137234-62-9
Antifungal drug with similar structure than fluconazole available for systemic, oral and intravenous use, and topically for ophthalmic purposes. A latest update no published data on excretion in breast milk were found. Pharmacokinetic data indicates that it may likely pass into the milk in amounts that could be significant.Authorized use in children as young as 2 years of age. It has been used in 10-months-old infants. Until more published data on this drug regarding breastfeeding is available, safer alternatives of better known drugs, should be preferable, especially during the neonatal period and in case of prematurity. The small dose and poor absorption into plasma of most ophthalmic preparations makes it unlikely the pass of the drug into breast milk in significant amount.

What should I do if I am breastfeeding mother and I am already exposed to Voriconazole Suspension?
Voriconazole Suspension is in the category of low risk, if you have already used it then its not a big deal if health and behavior of baby is good. However your health care provider shall be aware of the fact that you have used Voriconazole Suspension so you should inform him based on your convenience.
I am nursing mother and my doctor has suggested me to use Voriconazole Suspension, is it safe?
Voriconazole Suspension comes in category of low risk and if your doctor is aware that you are breastfeeding it should be ok to use without much concerns.
If I am using Voriconazole Suspension, will my baby need extra monitoring?
Not much monitoring required while using Voriconazole Suspension
Who can I talk to if I have questions about usage of Voriconazole Suspension in breastfeeding?
US
National Womens Health and Breastfeeding Helpline: 800-994-9662 (TDD 888-220-5446) 9 a.m. and 6 p.m. ET, Monday through Friday
UK
National Breastfeeding Helpline: 0300-100-0212 9.30am to 9.30pm, daily
Association of Breastfeeding Mothers: 0300-330-5453
La Leche League: 0345-120-2918
The Breastfeeding Network supporter line in Bengali and Sylheti: 0300-456-2421
National Childbirth Trust (NCT): 0300-330-0700
Australia
National Breastfeeding Helpline: 1800-686-268 24 hours a day, 7 days a week
Canada
Telehealth Ontario for breastfeeding: 1-866-797-0000 24 hours a day, 7 days a week
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