Azasan | Azathioprine Tablet Breastfeeding

It is a well known fact that breastfeeding is best source of nutrition for infants. Breast milk provides minerals, vitamins and antibodies in most acceptable format when they need it. Nutrition taken by mother passes to breast-milk and same thing applies to medicines taken by mothers. Not all drugs cause problem for baby but some do. Lets analyze if Azasan | Azathioprine Tablet is safe for baby while breastfed.

What is Azasan | Azathioprine Tablet used for?


: AZASAN is indicated as an adjunct for the prevention of rejection in renal homotransplantation. It is also indicated for the management of active rheumatoid arthritis to reduce signs and symptoms. Renal Homotransplantation: AZASAN is indicated as an adjunct for the prevention of rejection in renal homotransplantation. Experience with over 16,000 transplants shows a 5-year patient survival of 35% to 55%, but this is dependent on donor, match for HLA antigens, anti-donor or anti-B-cell alloantigen antibody, and other variables. The effect of azathioprine on these variables has not been tested in controlled trials. Rheumatoid Arthritis: AZASAN is indicated for the treatment of active rheumatoid arthritis (RA) to reduce signs and symptoms. Aspirin, nonsteroidal anti-inflammatory drugs and/or low dose glucocorticoids may be continued during treatment with AZASAN. The combined use of azathioprine with disease modifying anti-rheumatic drugs (DMARDs) has not been studied for either added benefit or unexpected adverse effects. The use of AZASAN with these agents cannot be recommended.

I am breastfeeding mother and I am using Azasan | Azathioprine Tablet. Can it have any bad effect on my kid? Shall I search for better alternative?

Azasan | Azathioprine Tablet safe for breastfeeding
Active ingredient in Azasan | Azathioprine Tablet is Azathioprine and based on our analysis of Azathioprine it appears that using Azasan | Azathioprine Tablet is safe in breastfeeding. Below is analysis of Azathioprine while breastfeeding.

Azasan | Azathioprine Tablet Breastfeeding Analsys


Azathioprine while Breastfeeding

Safe

CAS Number: 446-86-6

Even though it is metabolized to mercaptopurine, just tiny amounts of this drug have been found in breast milk (4 - 18 micrograms/liter). Among several breastfed infants of mothers who were treated with Azathioprine failed to be detected in the blood nor side effects were found. Long-term infectious diseases were not more common among exposed infants. Exposition would be minimized if nursing is resumed 3 hours after last dose.

Azasan | Azathioprine Tablet Breastfeeding Analsys - 2


Azathioprine while Breastfeeding

CAS Number: 446-86-6

Is Azasan | Azathioprine Tablet safe while breastfeeding

Most experts consider breastfeeding during azathioprine to be acceptable.[1][2][3][4][5][6][7][8] Studies in women with inflammatory bowel disease, systemic lupus erythematosus or transplantation taking doses of azathioprine up to 200 mg daily for immunosuppression have found either low or unmeasurable levels of the active metabolites in milk and infant serum. Some evidence indicates a lack of adverse effects on the health and development of infants exposed to azathioprine during breastfeeding up to 3.5 years of age, but long-term follow-up for effects such as carcinogenesis have not been performed. Mothers with decreased activity of the enzyme that detoxifies azathioprine metabolites may transmit higher levels of drug to their infants in breastmilk. Cases of mild, asymptomatic neutropenia have been reported, so it might be desirable to monitor exclusively breastfed infants with a complete blood count with differential, and liver function tests if azathioprine is used during lactation, although some authors feel that monitoring is unnecessary.[9] Avoiding breastfeeding for 4 hours after a dose should markedly decrease the dose received by the infant in breastmilk.[10]


What should I do if already breastfed my kid after using Azasan | Azathioprine Tablet?

It is always a good idea to keep your healthcare provider or doctor informed about your drug usage during pregnancy and breastfeeding but if you have not informed your doctor about Azasan | Azathioprine Tablet and have used it then do not panic as Azasan | Azathioprine Tablet is mostly safe in breastfeeding and should not cause any harm to your baby.


I am nursing mother and my doctor has suggested me to use Azasan | Azathioprine Tablet, is it safe?

Definitely, Azasan | Azathioprine Tablet is safe in lactation for baby. No wonder your doctor has recommended it.


If I am using Azasan | Azathioprine Tablet, will my baby need extra monitoring?

No extra baby monitoring required while mother is using Azasan | Azathioprine Tablet


Who can I talk to if I have questions about usage of Azasan | Azathioprine Tablet in breastfeeding?

US
National Womens Health and Breastfeeding Helpline: 800-994-9662 (TDD 888-220-5446) 9 a.m. and 6 p.m. ET, Monday through Friday

UK
National Breastfeeding Helpline: 0300-100-0212 9.30am to 9.30pm, daily
Association of Breastfeeding Mothers: 0300-330-5453
La Leche League: 0345-120-2918
The Breastfeeding Network supporter line in Bengali and Sylheti: 0300-456-2421
National Childbirth Trust (NCT): 0300-330-0700

Australia
National Breastfeeding Helpline: 1800-686-268 24 hours a day, 7 days a week

Canada
Telehealth Ontario for breastfeeding: 1-866-797-0000 24 hours a day, 7 days a week

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Azathioprine Sodium Injection, Powder, Lyophilized, For Solution