Alora | Estradiol Patch Breastfeeding
Modern medicine has evolved so much so that sooner or later every breastfeeding mother needs to take it in one form or other. Medication that is present in mothers blood will transfer into her breast milk to some extent. Most drugs do so at low levels and pose no real risk to infants but then there are some exceptions. In This post will discuss whether Alora | Estradiol Patch is safe in breast-feeding or not.

What is Alora | Estradiol Patch used for?


Alora is indicated in: Treatment of moderate to severe vasomotor symptoms associated with the menopause. Treatment of moderate to severe symptoms of vulvar and vaginal atrophy associated with the menopause. When prescribing solely for the treatment of symptoms of vulvar and vaginal atrophy, topical vaginal products should be considered. Treatment of hypoestrogenism due to hypogonadism, castration or primary ovarian failure. Prevention of postmenopausal osteoporosis. When prescribing solely for the prevention of postmenopausal osteoporosis, therapy should only be considered for women at significant risk of osteoporosis and non-estrogen medications should be carefully considered. The mainstays for decreasing the risk of postmenopausal osteoporosis are weight bearing exercise, adequate calcium and vitamin D intake, and, when indicated, pharmacologic therapy. Postmenopausal women require an average of 1500 mg/day of elemental calcium to remain in neutral calcium balance. Therefore, when not contraindicated, calcium supplementation may be helpful for women with suboptimal dietary intake. Vitamin D supplementation of 400-800 IU/day may also be required to ensure adequate daily intake in postmenopausal women.

Is Alora | Estradiol Patch usage safe while breastfeeding? If a lactating mother is using it can there be any effect on growth or development of infant?

Alora | Estradiol Patch low risk for breastfeeding
Estradiol is the one and only active ingredient present in Alora | Estradiol Patch. Estradiol in itself is a low risk drug for lactation so it is easy to understand that Alora | Estradiol Patch also comes in category of Low Risk item while breastfeeding. Below is the summary of Estradiol in breastfeeding.

Statement of Manufacturer/Labeler about breastfeeding usage
G. Nursing Mothers Estrogen administration to nursing mothers has been shown to decrease the quantity and quality of the milk. Detectable amounts of estrogens have been identified in the milk of mothers receiving estrogen therapy. Estrogens are not indicated for the prevention of postpartum breast engorgement. Caution should be exercised when Alora is administered to a nursing woman.

Alora | Estradiol Patch Breastfeeding Analsys


Estradiol while Breastfeeding

Low Risk

CAS Number: 50-28-2

A natural Estrogen that is marketed for oral, injection and topical administration (skin and vaginal).On the chemical form of valerate, it is used in association with a progestin as a combined birth-control compound (e.g. Estradiol + Dienogest) Estradiol is excreted into breast milk in clinically non-significant amount (Nilson 1978) and no problems have been observed in infants whose mothers were treated (Pinheiro 2016). Plasma levels of these infants were undetectable or very low (Pinheiro 2016). After administration in the form of transdermal patches milk levels have been undetectable (Pinheiro 2016, Perheentupa 2004). Despite these data, an older publication associated the use of transdermal estradiol with a case of jaundice and poor weight gain (Ball 1999).There is greater passage to milk when the administration is vaginal. There is evidence (albeit inconsistent) that estrogen-containing pills may decrease milk production, especially during the first few weeks postpartumThey may reduce the protein content of the milk. No problems have been observed in infants whose mothers were treated, except some cases of transient gynecomastia in infants whose mothers were receiving a higher dose than usual. Estrogen exposure in childhood or adolescence, does not influence the subsequent production of milk. The American Academy of Pediatrics states that this medication is usually compatible with breastfeeding.

Alora | Estradiol Patch Breastfeeding Analsys - 2


Estradiol while Breastfeeding

CAS Number: 50-28-2

Alora | Estradiol Patch and breastfeeding

Limited information on the use of estradiol during breastfeeding indicates that the route of administration and dosage form have influences on the amount transferred into breastmilk. Vaginal administration results in measurable amounts in milk, but transdermal patches do not. Maternal doses of up to 200 mcg daily transdermally do not increase estradiol or estriol in breastfed infants or cause any adverse effects in breastfed infants. Vaginal administration results in unpredictable peak times for estradiol in breastmilk, so timing of the dose with respect to breastfeeding is probably not useful. A case report of inadequate milk production and inadequate infant weight gain was possibly caused by transdermal estradiol initiated on the first day postpartum, but 2 small studies found no such effect when the drug was initiated after lactation was well established.

Is Alora | Estradiol Patch safe while breastfeeding

I am nursing mother and I have already used Alora | Estradiol Patch, what should I do?

During whole lactation period you shall first discuss with your doctor and then together you shall decide whether you shall take that drug or not however if you have already taken Alora | Estradiol Patch then you shall inform your doctor, But you should not be worried too much as Alora | Estradiol Patch comes in category of low risk drug.


I am nursing mother and my doctor has suggested me to use Alora | Estradiol Patch, is it safe?

Though Alora | Estradiol Patch dose not comes in category of safe drugs rather it comes in category of low risk but if your doctor is aware that you are breastfeeding your baby and has still recommended it then its advantages must be outweighing the risks.


If I am using Alora | Estradiol Patch, will my baby need extra monitoring?

Not much


Who can I talk to if I have questions about usage of Alora | Estradiol Patch in breastfeeding?

US
National Womens Health and Breastfeeding Helpline: 800-994-9662 (TDD 888-220-5446) 9 a.m. and 6 p.m. ET, Monday through Friday

UK
National Breastfeeding Helpline: 0300-100-0212 9.30am to 9.30pm, daily
Association of Breastfeeding Mothers: 0300-330-5453
La Leche League: 0345-120-2918
The Breastfeeding Network supporter line in Bengali and Sylheti: 0300-456-2421
National Childbirth Trust (NCT): 0300-330-0700

Australia
National Breastfeeding Helpline: 1800-686-268 24 hours a day, 7 days a week

Canada
Telehealth Ontario for breastfeeding: 1-866-797-0000 24 hours a day, 7 days a week

Drug Brands with same Active ingredients

Estrace | Estradiol Cream
Estra-50 | Estradiol Pellet Pellet, Implantable
Estradiol Film, Extended Release
Estradiol Insert
Vivelle-dot | Estradiol Patch, Extended Release
Estradiol Vaginal Inserts | Estradiol Tablet
Imvexxy | Estradiol Insert
Estrogen Phenolic | Estradiol, Liquid
Evamist | Estradiol Spray
Elestrin | Estradiol Gel, Metered
Menostar | Estradiol Patch
Estradiol Pellet