Estradiol Film, Extended Release Breastfeeding
There are high number of clear evidence that breastfeeding provides best nutrition that you can give to your baby. It is also evident that lactation is good for mothers health as well. Evolution has designed breastfeeding in a way that it caters all nutritional need of your child. However modern medicine is quite new for evolution, that is why mothers body is not well prepared to filter unnecessary chemical found in medicines. It becomes a necessity to figure out which drug is safe and which drug is dangerous for your newborn while nursing. In this article we will understand function of Estradiol Film, Extended Release and its suitability with breastfeeding.

What is Estradiol Film, Extended Release used for?


ESTRADIOL TRANSDERMAL SYSTEM is an estrogen indicated for: Treatment of moderate to severe vasomotor symptoms due to menopause ( 1.1 ) Prevention of postmenopausal osteoporosis ( 1.2 ) 1.1 Treatment of Moderate to Severe Vasomotor Symptoms Due to Menopause ESTRADIOL TRANSDERMAL SYSTEM is indicated for the treatment of moderate to severe vasomotor symptoms due to menopause. 1.2 Prevention of Postmenopausal Osteoporosis ESTRADIOL TRANSDERMAL SYSTEM is indicated for the prevention of postmenopausal osteoporosis. When prescribing solely for the prevention of postmenopausal osteoporosis, therapy should only be considered for women at significant risk of osteoporosis and non-estrogen medications should be carefully considered. Limitation of Use When prescribing solely for the prevention of postmenopausal osteoporosis, therapy should only be considered for women at significant risk of osteoporosis and non-estrogen medications should be carefully considered.

Estradiol Film, Extended Release while breastfeeding safe or not? Can there be any side effects for infant while using it during breastfeeding?

Estradiol Film, Extended Release low risk for breastfeeding
Estradiol is the one and only active ingredient present in Estradiol Film, Extended Release. Estradiol in itself is a low risk drug for lactation so it is easy to understand that Estradiol Film, Extended Release also comes in category of Low Risk item while breastfeeding. Below is the summary of Estradiol in breastfeeding.

Statement of Manufacturer/Labeler about breastfeeding usage
8.3 Nursing Mothers ESTRADIOL TRANSDERMAL SYSTEM should not be used during lactation. Estrogen administration to nursing women has been shown to decrease the quantity and quality of the breast milk. Detectable amounts of estrogens have been identified in the breast milk of women receiving estrogen therapy. Caution should be exercised when ESTRADIOL TRANSDERMAL SYSTEM is administered to a nursing woman.

Estradiol Film, Extended Release Breastfeeding Analsys


Estradiol while Breastfeeding

Low Risk

CAS Number: 50-28-2

A natural Estrogen that is marketed for oral, injection and topical administration (skin and vaginal).On the chemical form of valerate, it is used in association with a progestin as a combined birth-control compound (e.g. Estradiol + Dienogest) Estradiol is excreted into breast milk in clinically non-significant amount (Nilson 1978) and no problems have been observed in infants whose mothers were treated (Pinheiro 2016). Plasma levels of these infants were undetectable or very low (Pinheiro 2016). After administration in the form of transdermal patches milk levels have been undetectable (Pinheiro 2016, Perheentupa 2004). Despite these data, an older publication associated the use of transdermal estradiol with a case of jaundice and poor weight gain (Ball 1999).There is greater passage to milk when the administration is vaginal. There is evidence (albeit inconsistent) that estrogen-containing pills may decrease milk production, especially during the first few weeks postpartumThey may reduce the protein content of the milk. No problems have been observed in infants whose mothers were treated, except some cases of transient gynecomastia in infants whose mothers were receiving a higher dose than usual. Estrogen exposure in childhood or adolescence, does not influence the subsequent production of milk. The American Academy of Pediatrics states that this medication is usually compatible with breastfeeding.


Estradiol Film, Extended Release Breastfeeding Analsys - 2


Estradiol while Breastfeeding

CAS Number: 50-28-2

Is Estradiol Film, Extended Release safe while breastfeeding

Limited information on the use of estradiol during breastfeeding indicates that the route of administration and dosage form have influences on the amount transferred into breastmilk. Vaginal administration results in measurable amounts in milk, but transdermal patches do not. Maternal doses of up to 200 mcg daily transdermally do not increase estradiol or estriol in breastfed infants or cause any adverse effects in breastfed infants. Vaginal administration results in unpredictable peak times for estradiol in breastmilk, so timing of the dose with respect to breastfeeding is probably not useful. A case report of inadequate milk production and inadequate infant weight gain was possibly caused by transdermal estradiol initiated on the first day postpartum, but 2 small studies found no such effect when the drug was initiated after lactation was well established.


Estradiol Film, Extended Release safe for breastfeeding

What should I do if I am breastfeeding mother and I am already exposed to Estradiol Film, Extended Release?

Estradiol Film, Extended Release is in the category of low risk, if you have already used it then its not a big deal if health and behavior of baby is good. However your health care provider shall be aware of the fact that you have used Estradiol Film, Extended Release so you should inform him based on your convenience.


I am nursing mother and my doctor has suggested me to use Estradiol Film, Extended Release, is it safe?

Estradiol Film, Extended Release comes in category of low risk and if your doctor is aware that you are breastfeeding it should be ok to use without much concerns.


If I am using Estradiol Film, Extended Release, will my baby need extra monitoring?

Not much monitoring required while using Estradiol Film, Extended Release


Who can I talk to if I have questions about usage of Estradiol Film, Extended Release in breastfeeding?

US
National Womens Health and Breastfeeding Helpline: 800-994-9662 (TDD 888-220-5446) 9 a.m. and 6 p.m. ET, Monday through Friday

UK
National Breastfeeding Helpline: 0300-100-0212 9.30am to 9.30pm, daily
Association of Breastfeeding Mothers: 0300-330-5453
La Leche League: 0345-120-2918
The Breastfeeding Network supporter line in Bengali and Sylheti: 0300-456-2421
National Childbirth Trust (NCT): 0300-330-0700

Australia
National Breastfeeding Helpline: 1800-686-268 24 hours a day, 7 days a week

Canada
Telehealth Ontario for breastfeeding: 1-866-797-0000 24 hours a day, 7 days a week