Bethkis | Tobramycin Solution Breastfeeding
It is a well known fact that breastfeeding is best source of nutrition for infants. Breast milk provides minerals, vitamins and antibodies in most acceptable format when they need it. Nutrition taken by mother passes to breast-milk and same thing applies to medicines taken by mothers. Not all drugs cause problem for baby but some do. Lets analyze if Bethkis | Tobramycin Solution is safe for baby while breastfed.

What is Bethkis | Tobramycin Solution used for?


BETHKIS is indicated for the management of cystic fibrosis patients with Pseudomonas aeruginosa. Safety and efficacy have not been demonstrated in patients under the age of six years, patients with FEV1 less than 40% or greater than 80% predicted, or patients colonized with Burkholderia cepacia [s ee Clinical Studies (14)]. BETHKIS is an inhaled aminoglycoside antibacterial indicated for the management of cystic fibrosis patients with Pseudomonas aeruginosa. (1) Safety and efficacy have not been demonstrated in patients under the age of six years, patients with a forced expiratory volume in one second (FEV1) less than 40% or greater than 80% predicted, or patients colonized with Burkholderia cepacia. (1)

I am breastfeeding mother and I am using Bethkis | Tobramycin Solution. Can it have any bad effect on my kid? Shall I search for better alternative?

Bethkis | Tobramycin Solution safe for breastfeeding
Active ingredient in Bethkis | Tobramycin Solution is Tobramycin and based on our analysis of Tobramycin it appears that using Bethkis | Tobramycin Solution is safe in breastfeeding. Below is analysis of Tobramycin while breastfeeding.

Statement of Manufacturer/Labeler about breastfeeding usage
8.3 Nursing Mothers It is not known if tobramycin will reach sufficient concentrations after administration by inhalation to be excreted in human breast milk. Because of the potential for ototoxicity and nephrotoxicity in infants, a decision should be made whether to terminate nursing or discontinue tobramycin therapy, taking into account the importance of the drug to the mother.

Bethkis | Tobramycin Solution Breastfeeding Analsys


Tobramycin while Breastfeeding

Safe

CAS Number: 32986-56-4

Excreted into breast milk in non-significant amount without harm effects observed among breastfed infants of mothers treated with Tobramycin. In addition, a low oral bioavailability renders concentration in the infant's plasma be nil or low. Be aware of false negative results that may be obtained from infants with bacterial cultures when the mother is on antibiotics and higher risk of acute diarrhea by alteration of normal gut flora. When used in eye drops, because of a low dose and topical application with minimal absorption in the serum, it is compatible while breastfeeding.

Bethkis | Tobramycin Solution Breastfeeding Analsys - 2


Tobramycin while Breastfeeding

CAS Number: 32986-56-4

Is Bethkis | Tobramycin Solution safe while breastfeeding

Tobramycin is poorly excreted into breastmilk. Newborn infants apparently absorb small amounts of other aminoglycosides, but serum levels with typical three times per day dosages are far below those attained when treating newborn infections and systemic effects of tobramycin are unlikely. Older infants would be expected to absorb even less tobramycin. Because there is little variability in the milk tobramycin levels during multiple daily dose regimens, timing breastfeeding with respect to the dose is of little or no benefit in reducing infant exposure. Data are not available with single daily dose regimens. Monitor the infant for possible effects on the gastrointestinal flora, such as diarrhea, candidiasis (e.g., thrush, diaper rash) or rarely, blood in the stool indicating possible antibiotic-associated colitis. Maternal use of an ear drop or eye drop that contains tobramycin presents little or no risk for the nursing infant [4]

Bethkis | Tobramycin Solution safe for breastfeeding

What should I do if already breastfed my kid after using Bethkis | Tobramycin Solution?

It is always a good idea to keep your healthcare provider or doctor informed about your drug usage during pregnancy and breastfeeding but if you have not informed your doctor about Bethkis | Tobramycin Solution and have used it then do not panic as Bethkis | Tobramycin Solution is mostly safe in breastfeeding and should not cause any harm to your baby.


I am nursing mother and my doctor has suggested me to use Bethkis | Tobramycin Solution, is it safe?

Definitely, Bethkis | Tobramycin Solution is safe in lactation for baby. No wonder your doctor has recommended it.


If I am using Bethkis | Tobramycin Solution, will my baby need extra monitoring?

No extra baby monitoring required while mother is using Bethkis | Tobramycin Solution


Who can I talk to if I have questions about usage of Bethkis | Tobramycin Solution in breastfeeding?

US
National Womens Health and Breastfeeding Helpline: 800-994-9662 (TDD 888-220-5446) 9 a.m. and 6 p.m. ET, Monday through Friday

UK
National Breastfeeding Helpline: 0300-100-0212 9.30am to 9.30pm, daily
Association of Breastfeeding Mothers: 0300-330-5453
La Leche League: 0345-120-2918
The Breastfeeding Network supporter line in Bengali and Sylheti: 0300-456-2421
National Childbirth Trust (NCT): 0300-330-0700

Australia
National Breastfeeding Helpline: 1800-686-268 24 hours a day, 7 days a week

Canada
Telehealth Ontario for breastfeeding: 1-866-797-0000 24 hours a day, 7 days a week

Drug Brands with same Active ingredients

Tobi | Tobramycin Solution
Tobramycin Inhalation Solution Pak | Tobramycin Solution
Tobrex | Tobramycin Solution/ Drops
Tobi Podhaler | Tobramycin Capsule