Most health expert recommend six month of exclusive breastfeeding but statics suggest that numbers are not good, almost 95% mothers start breastfeeding but this number drops to 40% in first three month and further it drops to 15% till fifth month. Sometime its due to need of medication usage. Because of these statics its important to provide good information on safety of drugs in breastfeeding so that it can be improved when possible. In this FAQ sheet we will discuss about exposure to Tobi Podhaler | Tobramycin Capsule while breastfeeding. We will also discuss about common side effects and warnings associated with Tobi Podhaler | Tobramycin Capsule.
What is Tobi Podhaler | Tobramycin Capsule used for?
TOBI Podhaler is indicated for the management of cystic fibrosis patients with Pseudomonas aeruginosa. Safety and efficacy have not been demonstrated in patients under the age of 6 years, patients with forced expiratory volume in 1 second (FEV1) <25% or >80% predicted, or patients colonized with Burkholderia cepacia [see Clinical Studies (14)]. TOBI Podhaler is an antibacterial aminoglycoside indicated for the management of cystic fibrosis patients with Pseudomonas aeruginosa. Safety and efficacy have not been demonstrated in patients under the age of 6 years, patients with forced expiratory volume in 1 second (FEV1) <25% or >80%, or patients colonized with Burkholderia cepacia (1)
Tobi Podhaler | Tobramycin Capsule while breastfeeding safe or not? Can there be any side effects for infant while using it during breastfeeding?
As per our analysis Tobi Podhaler | Tobramycin Capsule contains only one ingredient and that is Tobramycin. We have analyzed Tobramycin and it seems to be safe to use Tobramycin while breastfeeding, that means usage of Tobi Podhaler | Tobramycin Capsule shall be safe while breastfeeding. Below you can check more details of Tobramycin usage in breastfeeding. We recommend you to go through provided detailed analysis as below take decision accordingly.
Statement of Manufacturer/Labeler about breastfeeding usage
8.3 Nursing Mothers The amount of tobramycin excreted in human breast milk after administration by inhalation is not known. Because of the potential for ototoxicity and nephrotoxicity in infants, a decision should be made whether to terminate nursing or discontinue the drug, taking into account the importance of the drug to the mother.
Tobi Podhaler | Tobramycin Capsule Breastfeeding Analsys
SafeCAS Number: 32986-56-4
Excreted into breast milk in non-significant amount without harm effects observed among breastfed infants of mothers treated with Tobramycin. In addition, a low oral bioavailability renders concentration in the infant's plasma be nil or low. Be aware of false negative results that may be obtained from infants with bacterial cultures when the mother is on antibiotics and higher risk of acute diarrhea by alteration of normal gut flora. When used in eye drops, because of a low dose and topical application with minimal absorption in the serum, it is compatible while breastfeeding.
Tobi Podhaler | Tobramycin Capsule Breastfeeding Analsys - 2
CAS Number: 32986-56-4
Tobramycin is poorly excreted into breastmilk. Newborn infants apparently absorb small amounts of other aminoglycosides, but serum levels with typical three times per day dosages are far below those attained when treating newborn infections and systemic effects of tobramycin are unlikely. Older infants would be expected to absorb even less tobramycin. Because there is little variability in the milk tobramycin levels during multiple daily dose regimens, timing breastfeeding with respect to the dose is of little or no benefit in reducing infant exposure. Data are not available with single daily dose regimens. Monitor the infant for possible effects on the gastrointestinal flora, such as diarrhea, candidiasis (e.g., thrush, diaper rash) or rarely, blood in the stool indicating possible antibiotic-associated colitis. Maternal use of an ear drop or eye drop that contains tobramycin presents little or no risk for the nursing infant [4]
What should I do if already breastfed my kid after using Tobi Podhaler | Tobramycin Capsule?
Tobi Podhaler | Tobramycin Capsule is safe in breastfeeding and should not create any health problem for your baby but in case you feel any health issue associated with Tobi Podhaler | Tobramycin Capsule you should contact your doctor or health care provider. Be it pregnancy or lactation you shall keep your doctor informed.
I am nursing mother and my doctor has suggested me to use Tobi Podhaler | Tobramycin Capsule, is it safe?
Usage of Tobi Podhaler | Tobramycin Capsule is safe for nursing mothers and baby, No worries.
If I am using Tobi Podhaler | Tobramycin Capsule, will my baby need extra monitoring?
No
Who can I talk to if I have questions about usage of Tobi Podhaler | Tobramycin Capsule in breastfeeding?
US
National Womens Health and Breastfeeding Helpline: 800-994-9662 (TDD 888-220-5446) 9 a.m. and 6 p.m. ET, Monday through Friday
UK
National Breastfeeding Helpline: 0300-100-0212 9.30am to 9.30pm, daily
Association of Breastfeeding Mothers: 0300-330-5453
La Leche League: 0345-120-2918
The Breastfeeding Network supporter line in Bengali and Sylheti: 0300-456-2421
National Childbirth Trust (NCT): 0300-330-0700
Australia
National Breastfeeding Helpline: 1800-686-268 24 hours a day, 7 days a week
Canada
Telehealth Ontario for breastfeeding: 1-866-797-0000 24 hours a day, 7 days a week