Irinotecan Hydrochloride 100 Mg/5 Ml | Irinotecan Hydrochloride Injection Breastfeeding

For most of the drugs advantages of taking medications overweighs the potential risks however some drugs could be really dangerous for breastfed baby hence every medication shall be considered separately. In this page we will discuss about purpose of Irinotecan Hydrochloride 100 Mg/5 Ml | Irinotecan Hydrochloride Injection and its risk associated with lactation. We will also discuss the usage of Irinotecan Hydrochloride 100 Mg/5 Ml | Irinotecan Hydrochloride Injection and some common side effects associated with Irinotecan Hydrochloride 100 Mg/5 Ml | Irinotecan Hydrochloride Injection.

What is Irinotecan Hydrochloride 100 Mg/5 Ml | Irinotecan Hydrochloride Injection ?


Irinotecan hydrochloride injection is a topoisomerase inhibitor indicated for: • Patients with metastatic carcinoma of the colon or rectum whose disease has recurred or progressed following initial fluorouracil-based therapy. (1) • Irinotecan hydrochloride injection is indicated for patients with metastatic carcinoma of the colon or rectum whose disease has recurred or progressed following initial fluorouracil-based therapy.

Is using Irinotecan Hydrochloride 100 Mg/5 Ml | Irinotecan Hydrochloride Injection safe or dangerous while breastfeeding?

Irinotecan Hydrochloride 100 Mg/5 Ml | Irinotecan Hydrochloride Injection contains Irinotecan hydrochloride as active ingredients, . We do not have safety rating of Irinotecan hydrochloride but we do have analysis of Irinotecan hydrochloride, which is used in manufacturing of Irinotecan Hydrochloride 100 Mg/5 Ml | Irinotecan Hydrochloride Injection. You can get a good idea about Irinotecan Hydrochloride 100 Mg/5 Ml | Irinotecan Hydrochloride Injection usage while breastfeeding by going through our detailed analysis as below.

Statement of Manufacturer/Labeler about breastfeeding usage
8.3 Nursing Mothers Radioactivity appeared in rat milk within 5 minutes of intravenous administration of radiolabeled irinotecan and was concentrated up to 65-fold at 4 hours after administration relative to plasma concentrations. It is not known whether this drug is excreted in human milk. Because many drugs are excreted in human milk and because of the potential for serious adverse reactions in nursing infants from irinotecan hydrochloride, a decision should be made whether to discontinue nursing or discontinue the drug, taking into account the importance of the drug to the mother.

Irinotecan Hydrochloride 100 Mg/5 Ml | Irinotecan Hydrochloride Injection Breastfeeding Analsys


Irinotecan hydrochloride while Breastfeeding

CAS Number: 97682-44-5 86639-52-

Limited data indicate that irinotecan is found in breastmilk for 2 days and its active metabolite is found in breastmilk for up to a week after a dose of 60 mg/square meter, although the highest amounts occur during the first 4 days after a dose. Higher maternal doses have not been studied and the oral absorption and toxicity in breastfed infants are not known. Based on this limited evidence, it appears that breastfeeding should be avoided for at least a week after a dose of irinotecan 60 mg/square meter. Higher dosages probably require a longer abstinence period. Some authors recommend discontinuing breastfeeding during irinotecan therapy.[1] Chemotherapy may adversely affect the normal microbiome and chemical makeup of breastmilk.[2] Women who receive chemotherapy during pregnancy are more likely to have difficulty nursing their infant.[3]


What should I do if I am breastfeeding mother and I am already exposed to Irinotecan Hydrochloride 100 Mg/5 Ml | Irinotecan Hydrochloride Injection?

We are not completely sure about safety of Irinotecan Hydrochloride 100 Mg/5 Ml | Irinotecan Hydrochloride Injection in breastfeeding. We would suggest you to contact your doctor or health care provider and explain your situation with Irinotecan Hydrochloride 100 Mg/5 Ml | Irinotecan Hydrochloride Injection. If you observe anything abnormal with your baby please call 911 or contact emergency services in your area.


My doctor has prescribed me Irinotecan Hydrochloride 100 Mg/5 Ml | Irinotecan Hydrochloride Injection, what should I do?

If your doctor considers Irinotecan Hydrochloride 100 Mg/5 Ml | Irinotecan Hydrochloride Injection safe enough to prescribe for you that means its benefits outweigh its known risks.


If I am using Irinotecan Hydrochloride 100 Mg/5 Ml | Irinotecan Hydrochloride Injection, will my baby need extra monitoring?

Not Sure, Please check with your doctor or lactation consultant.


Who can I talk to if I have questions about usage of Irinotecan Hydrochloride 100 Mg/5 Ml | Irinotecan Hydrochloride Injection in breastfeeding?

US
National Womens Health and Breastfeeding Helpline: 800-994-9662 (TDD 888-220-5446) 9 a.m. and 6 p.m. ET, Monday through Friday

UK
National Breastfeeding Helpline: 0300-100-0212 9.30am to 9.30pm, daily
Association of Breastfeeding Mothers: 0300-330-5453
La Leche League: 0345-120-2918
The Breastfeeding Network supporter line in Bengali and Sylheti: 0300-456-2421
National Childbirth Trust (NCT): 0300-330-0700

Australia
National Breastfeeding Helpline: 1800-686-268 24 hours a day, 7 days a week

Canada
Telehealth Ontario for breastfeeding: 1-866-797-0000 24 hours a day, 7 days a week

Drug Brands with same Active ingredients

Onivyde | Irinotecan Hydrochloride Injection, Powder, For Solution