Onivyde | Irinotecan Hydrochloride Injection, Powder, For Solution Breastfeeding

There are high number of clear evidence that breastfeeding provides best nutrition that you can give to your baby. It is also evident that lactation is good for mothers health as well. Evolution has designed breastfeeding in a way that it caters all nutritional need of your child. However modern medicine is quite new for evolution, that is why mothers body is not well prepared to filter unnecessary chemical found in medicines. It becomes a necessity to figure out which drug is safe and which drug is dangerous for your newborn while nursing. In this article we will understand function of Onivyde | Irinotecan Hydrochloride Injection, Powder, For Solution and its suitability with breastfeeding.

What is Onivyde | Irinotecan Hydrochloride Injection, Powder, For Solution used for?


ONIVYDE® is indicated, in combination with fluorouracil and leucovorin, for the treatment of patients with metastatic adenocarcinoma of the pancreas after disease progression following gemcitabine-based therapy. Limitation of Use: ONIVYDE is not indicated as a single agent for the treatment of patients with metastatic adenocarcinoma of the pancreas [see Clinical Studies (14)]. ONIVYDE is a topoisomerase inhibitor indicated, in combination with fluorouracil and leucovorin, for the treatment of patients with metastatic adenocarcinoma of the pancreas after disease progression following gemcitabine-based therapy. (1) Limitation of Use: ONIVYDE is not indicated as a single agent for the treatment of patients with metastatic adenocarcinoma of the pancreas. (1)

Can I continue breastfeeding if I am using Onivyde | Irinotecan Hydrochloride Injection, Powder, For Solution? How long does it stays in breast milk?

Onivyde | Irinotecan Hydrochloride Injection, Powder, For Solution contains Irinotecan hydrochloride as active ingredients, . We do not have safety rating of Irinotecan hydrochloride but we do have analysis of Irinotecan hydrochloride, which is used in manufacturing of Onivyde | Irinotecan Hydrochloride Injection, Powder, For Solution. You can get a good idea about Onivyde | Irinotecan Hydrochloride Injection, Powder, For Solution usage while breastfeeding by going through our detailed analysis as below.

Onivyde | Irinotecan Hydrochloride Injection, Powder, For Solution Breastfeeding Analsys


Irinotecan hydrochloride while Breastfeeding

CAS Number: 97682-44-5 86639-52-

Limited data indicate that irinotecan is found in breastmilk for 2 days and its active metabolite is found in breastmilk for up to a week after a dose of 60 mg/square meter, although the highest amounts occur during the first 4 days after a dose. Higher maternal doses have not been studied and the oral absorption and toxicity in breastfed infants are not known. Based on this limited evidence, it appears that breastfeeding should be avoided for at least a week after a dose of irinotecan 60 mg/square meter. Higher dosages probably require a longer abstinence period. Some authors recommend discontinuing breastfeeding during irinotecan therapy.[1] Chemotherapy may adversely affect the normal microbiome and chemical makeup of breastmilk.[2] Women who receive chemotherapy during pregnancy are more likely to have difficulty nursing their infant.[3]

Is Onivyde | Irinotecan Hydrochloride Injection, Powder, For Solution safe while breastfeeding

What should I do if I am breastfeeding mother and I am already exposed to Onivyde | Irinotecan Hydrochloride Injection, Powder, For Solution?

We are not completely sure about safety of Onivyde | Irinotecan Hydrochloride Injection, Powder, For Solution in breastfeeding. We would suggest you to contact your doctor or health care provider and explain your situation with Onivyde | Irinotecan Hydrochloride Injection, Powder, For Solution. If you observe anything abnormal with your baby please call 911 or contact emergency services in your area.


My doctor has prescribed me Onivyde | Irinotecan Hydrochloride Injection, Powder, For Solution, what should I do?

If your doctor considers Onivyde | Irinotecan Hydrochloride Injection, Powder, For Solution safe enough to prescribe for you that means its benefits outweigh its known risks.


If I am using Onivyde | Irinotecan Hydrochloride Injection, Powder, For Solution, will my baby need extra monitoring?

Not Sure, Please check with your doctor or lactation consultant.


Who can I talk to if I have questions about usage of Onivyde | Irinotecan Hydrochloride Injection, Powder, For Solution in breastfeeding?

US
National Womens Health and Breastfeeding Helpline: 800-994-9662 (TDD 888-220-5446) 9 a.m. and 6 p.m. ET, Monday through Friday

UK
National Breastfeeding Helpline: 0300-100-0212 9.30am to 9.30pm, daily
Association of Breastfeeding Mothers: 0300-330-5453
La Leche League: 0345-120-2918
The Breastfeeding Network supporter line in Bengali and Sylheti: 0300-456-2421
National Childbirth Trust (NCT): 0300-330-0700

Australia
National Breastfeeding Helpline: 1800-686-268 24 hours a day, 7 days a week

Canada
Telehealth Ontario for breastfeeding: 1-866-797-0000 24 hours a day, 7 days a week

Drug Brands with same Active ingredients

Irinotecan Hydrochloride 40 Mg/2 Ml | Irinotecan Hydrochloride Injection
Irinotecan Hydrochloride 100 Mg/5 Ml | Irinotecan Hydrochloride Injection
Onivyde | Irinotecan Hydrochloride Injection, Powder, For Solution