Medroxyprogesterone Acetate Injection, Suspension, Extended Release Breastfeeding
It is recommended to breastfeed exclusively for six months and then while introducing to other food sources extend it to twelve months. In this duration most mothers will need help of some sort of medication, It could be for short term like could and flue or it could be something chronic like Arthritis or Diabetes and here comes the question of safety of medication in use. In this post we will figure out what is Medroxyprogesterone Acetate Injection, Suspension, Extended Release and whether its safe to use Medroxyprogesterone Acetate Injection, Suspension, Extended Release while nursing or not.

What is Medroxyprogesterone Acetate Injection, Suspension, Extended Release used for?


Medroxyprogesterone acetate is indicated only for the prevention of pregnancy. The loss of bone mineral density (BMD) in women of all ages and the impact on peak bone mass in adolescents should be considered, along with the decrease in BMD that occurs during pregnancy and/or lactation, in the risk/benefit assessment for women who use Medroxyprogesterone acetate long-term [see Warnings and Precautions (5.1)]. Medroxyprogesterone acetate is a progestin indicated only for the prevention of pregnancy. (1)

Is using Medroxyprogesterone Acetate Injection, Suspension, Extended Release safe or dangerous while breastfeeding?

Medroxyprogesterone Acetate Injection, Suspension, Extended Release safe for breastfeeding
As per our analysis Medroxyprogesterone Acetate Injection, Suspension, Extended Release contains only one ingredient and that is Medroxyprogesterone acetate. We have analyzed Medroxyprogesterone acetate and it seems to be safe to use Medroxyprogesterone acetate while breastfeeding, that means usage of Medroxyprogesterone Acetate Injection, Suspension, Extended Release shall be safe while breastfeeding. Below you can check more details of Medroxyprogesterone acetate usage in breastfeeding. We recommend you to go through provided detailed analysis as below take decision accordingly.

Statement of Manufacturer/Labeler about breastfeeding usage
8.3 Nursing Mothers Detectable amounts of drug have been identified in the milk of mothers receiving Medroxyprogesterone acetate. [See Warnings and Precautions (5.13).]

Medroxyprogesterone Acetate Injection, Suspension, Extended Release Breastfeeding Analsys


Medroxyprogesterone acetate while Breastfeeding

Safe

CAS Number: 71-58-9

Is Medroxyprogesterone Acetate Injection, Suspension, Extended Release safe while breastfeeding

Synthetic progestin similar to progesterone that is used in uterine bleeding, dysmenorrhea, infertility and contraception.For contraception is used as a single drug or in combination with estrogen (e.g. Estradiol + Medroxyprogesterone).For oral use or long-acting injectable administration (Intramuscular or subcutaneous). It is excreted into breast milk in clinically non-significant amount, and, no problems have been observed in infants whose mothers who were treated with this medication. Plasma levels of these infants were undetectable or very low.There may be increased prolactin and milk production in women who receive medroxyprogesterone. Although it has not been shown effects on production and duration of breastfeeding when administered at any time postpartum, it is still controversial on if it really decreases milk production when progestins are used before a fully establishment of breastfeeding has occurred. Therefore, experts’ protocols by WHO and ABM advise to avoiding it until breastfeeding is fully developed (4-6 weeks). During lactation progestin-only drugs are preferred or in combination with estrogen for birth control, but whatever, the ones with the lower doses of estrogen should be used.For the first 6 weeks postpartum, non-hormonal methods are of choise. Hormone containing contraceptives do not affect the composition of milk, minerals (Mg, Fe, Cu, Ca, P) fat, lactose and calories but only a few the proteins. WHO List of Essential Medicines 2002: rates it as compatible with breastfeeding after the 6th postnatal week.


Medroxyprogesterone Acetate Injection, Suspension, Extended Release Breastfeeding Analsys - 2


Medroxyprogesterone acetate while Breastfeeding

CAS Number: 71-58-9

Medroxyprogesterone Acetate Injection, Suspension, Extended Release safe for breastfeeding

Although nonhormonal methods are preferred during breastfeeding, progestin-only contraceptives such as depot medroxyprogesterone acetate (DMPA) are considered the hormonal contraceptives of choice during all stages of lactation. Fair quality evidence indicates that DMPA does not adversely affect the composition of milk, the growth and development of the infant, or the milk supply.[1][2][3][4] Some evidence indicates that progestin-only contraceptives may offer protection against bone mineral density loss during lactation, or at least do not exacerbate it.[5][6][7] The timing of initiation of DMPA is controversial.[8] The product labeling states that it should be started no sooner than 6 weeks postpartum, based on data submitted for product approval. Studies of fair quality seem to indicate that concerns about immediate adverse effects on the infants is unfounded; however, starting too soon theoretically could affect the newborn infant adversely because of slower metabolism of the drug than older infants. Of concern is that no data exist on the effects of progesterone on brain and liver development at this age. Administration sooner than 6 weeks postpartum could interfere with the exclusivity or duration of lactation. A systematic review of studies using early postpartum initiation of DMPA concluded that all of the studies were of low quality and inadequate to disprove the concern about DMPA's effects on milk production if given sooner than 6 weeks after delivery.[9] A subsequent study raised the possibility of a slight reduction in breastfeeding duration in women given DMPA before hospital discharge,[10] and another study found that breastfeeding was less like to be initiated if mothers received immediate postpartum DMPA.[11] Expert opinion in the United States holds that the risks of progestin-only contraceptive products usually are acceptable for nursing mothers at any time postpartum.[12]The World Health Organization recommends that injectable depot medroxyprogesterone acetate should not used before 6 weeks postpartum.[13]



What if I already have used Medroxyprogesterone Acetate Injection, Suspension, Extended Release?

It is always a good idea to keep your healthcare provider or doctor informed about your drug usage during pregnancy and breastfeeding but if you have not informed your doctor about Medroxyprogesterone Acetate Injection, Suspension, Extended Release and have used it then do not panic as Medroxyprogesterone Acetate Injection, Suspension, Extended Release is mostly safe in breastfeeding and should not cause any harm to your baby.


My doctor has prescribed me Medroxyprogesterone Acetate Injection, Suspension, Extended Release, what should I do?

Usage of Medroxyprogesterone Acetate Injection, Suspension, Extended Release is safe for nursing mothers and baby, No worries.


If I am using Medroxyprogesterone Acetate Injection, Suspension, Extended Release, will my baby need extra monitoring?

No


Who can I talk to if I have questions about usage of Medroxyprogesterone Acetate Injection, Suspension, Extended Release in breastfeeding?

US
National Womens Health and Breastfeeding Helpline: 800-994-9662 (TDD 888-220-5446) 9 a.m. and 6 p.m. ET, Monday through Friday

UK
National Breastfeeding Helpline: 0300-100-0212 9.30am to 9.30pm, daily
Association of Breastfeeding Mothers: 0300-330-5453
La Leche League: 0345-120-2918
The Breastfeeding Network supporter line in Bengali and Sylheti: 0300-456-2421
National Childbirth Trust (NCT): 0300-330-0700

Australia
National Breastfeeding Helpline: 1800-686-268 24 hours a day, 7 days a week

Canada
Telehealth Ontario for breastfeeding: 1-866-797-0000 24 hours a day, 7 days a week