American Academy of Pediatrics and other medical experts exclusively recommend to breastfeed the baby for first 6 months. Once you introduce baby to other foods it is recommended to breastfeed for at least first year of babys life. Taking medication while breastfeeding could be tricky as most drugs pass in breast milk. In this article we will evaluate Precedex | Dexmedetomidine Hydrochloride Injection for its safety in breastfeeding.
What is Precedex | Dexmedetomidine Hydrochloride Injection used for?
Precedex is a relatively selective alpha2-adrenergic agonist indicated for: •Sedation of initially intubated and mechanically ventilated patients during treatment in an intensive care setting. Administer Precedex by continuous infusion not to exceed 24 hours. (1.1) •Sedation of non-intubated patients prior to and/or during surgical and other procedures. (1.2) 1.1 Intensive Care Unit Sedation PrecedexTM is indicated for sedation of initially intubated and mechanically ventilated patients during treatment in an intensive care setting. Precedex should be administered by continuous infusion not to exceed 24 hours. Precedex has been continuously infused in mechanically ventilated patients prior to extubation, during extubation, and post-extubation. It is not necessary to discontinue Precedex prior to extubation. 1.2 Procedural Sedation Precedex is indicated for sedation of non-intubated patients prior to and/or during surgical and other procedures.
1.1 Intensive Care Unit Sedation PrecedexTM is indicated for sedation of initially intubated and mechanically ventilated patients during treatment in an intensive care setting. Precedex should be administered by continuous infusion not to exceed 24 hours. Precedex has been continuously infused in mechanically ventilated patients prior to extubation, during extubation, and post-extubation. It is not necessary to discontinue Precedex prior to extubation.
1.2 Procedural Sedation Precedex is indicated for sedation of non-intubated patients prior to and/or during surgical and other procedures.
Is using Precedex | Dexmedetomidine Hydrochloride Injection unsafe in breastfeeding? Can there be bad consequences for baby if I use it while breastfeeding?
Precedex | Dexmedetomidine Hydrochloride Injection contains Dexmedetomidine as active ingredients, . We do not have safety rating of Dexmedetomidine but we do have analysis of Dexmedetomidine, which is used in manufacturing of Precedex | Dexmedetomidine Hydrochloride Injection. You can get a good idea about Precedex | Dexmedetomidine Hydrochloride Injection usage while breastfeeding by going through our detailed analysis as below.
Statement of Manufacturer/Labeler about breastfeeding usage
8.3 Nursing Mothers It is not known whether Precedex is excreted in human milk. Radio-labeled dexmedetomidine administered subcutaneously to lactating female rats was excreted in milk. Because many drugs are excreted in human milk, caution should be exercised when Precedex is administered to a nursing woman.
Precedex | Dexmedetomidine Hydrochloride Injection Breastfeeding Analsys
CAS Number: 113775-47-6
Limited data indicate that very small amounts of dexmedetomidine are excreted into breastmilk for 6 hours after the end of an infusion. Because of the small amounts of colostrum secreted in the first day postpartum, the dose received by a neonate is unlikely to be of any consequence when the drug is used during delivery. The drug is absent from breastmilk by 24 hours after the end of an infusion. Dexmedetomidine would not be expected to cause adverse effects in breastfed infants or neonates.
I already used Precedex | Dexmedetomidine Hydrochloride Injection and meanwhile I breastfed my baby should I be concerned?
We are not completely sure about safety of Precedex | Dexmedetomidine Hydrochloride Injection in breastfeeding. We would suggest you to contact your doctor or health care provider and explain your situation with Precedex | Dexmedetomidine Hydrochloride Injection. If you observe anything abnormal with your baby please call 911 or contact emergency services in your area.
My health care provider has asked me to use Precedex | Dexmedetomidine Hydrochloride Injection, what to do?
If your doctor considers Precedex | Dexmedetomidine Hydrochloride Injection safe enough to prescribe for you that means its benefits outweigh its known risks.
If I am using Precedex | Dexmedetomidine Hydrochloride Injection, will my baby need extra monitoring?
Not Sure, Please check with your doctor or lactation consultant.
Who can I talk to if I have questions about usage of Precedex | Dexmedetomidine Hydrochloride Injection in breastfeeding?
US
National Womens Health and Breastfeeding Helpline: 800-994-9662 (TDD 888-220-5446) 9 a.m. and 6 p.m. ET, Monday through Friday
UK
National Breastfeeding Helpline: 0300-100-0212 9.30am to 9.30pm, daily
Association of Breastfeeding Mothers: 0300-330-5453
La Leche League: 0345-120-2918
The Breastfeeding Network supporter line in Bengali and Sylheti: 0300-456-2421
National Childbirth Trust (NCT): 0300-330-0700
Australia
National Breastfeeding Helpline: 1800-686-268 24 hours a day, 7 days a week
Canada
Telehealth Ontario for breastfeeding: 1-866-797-0000 24 hours a day, 7 days a week