Zebutal | Butalbital, Acetaminophen And Caffeine Capsule Breastfeeding

Modern medicine has evolved so much so that sooner or later every breastfeeding mother needs to take it in one form or other. Medication that is present in mothers blood will transfer into her breast milk to some extent. Most drugs do so at low levels and pose no real risk to infants but then there are some exceptions. In This post will discuss whether Zebutal | Butalbital, Acetaminophen And Caffeine Capsule is safe in breast-feeding or not.

What is Zebutal | Butalbital, Acetaminophen And Caffeine Capsule used for?


Zebutal ® (butalbital, acetaminophen and caffeine capsules) USP 50 mg/325 mg/40 mg is indicated for the relief of the symptom complex of tension (or muscle contraction) headache. Evidence supporting the efficacy and safety of this combination product in the treatment of multiple recurrent headaches is unavailable. Caution in this regard is required because butalbital is habit-forming and potentially abusable.

Is Zebutal | Butalbital, Acetaminophen And Caffeine Capsule safe to use while breastfeeding? Can it interfere with growth and development of my kid?

Zebutal | Butalbital, Acetaminophen And Caffeine Capsule low risk for breastfeeding
Task to evaluate the effect of Zebutal | Butalbital, Acetaminophen And Caffeine Capsule is quite difficult as it consist mainly 3 ingredients. However we have analyzed all 3 active ingredients and have reached a conclusion that Zebutal | Butalbital, Acetaminophen And Caffeine Capsule poses low risk while breastfeeding. Below we have summarized our analysis of each 3 ingredients.

Statement of Manufacturer/Labeler about breastfeeding usage
Nursing Mothers Caffeine, barbiturates and acetaminophen are excreted in breast milk in small amounts, but the significance of their effects on nursing infants is not known. Because of potential for serious adverse reactions in nursing infants from butalbital, acetaminophen and caffeine, a decision should be made whether to discontinue nursing or to discontinue the drug, taking into account the importance of the drug to the mother.

Zebutal | Butalbital, Acetaminophen And Caffeine Capsule Breastfeeding Analsys


Butalbital while Breastfeeding

Low Risk

CAS Number: 77-26-9

Commercialized in association with other drugs for migraine treatment. Multiple drug compounds are not advisable. Caffeine may be a part of it (100 mg each tablet) and may be a cause of irritability to the infant. (See Caffeine)

Acetaminophen while Breastfeeding

Safe

CAS Number: 103-90-2

Excreted in very low amount into breast milk. Infant intake may be lower than 4% of usual pediatric dose. The American Academy of Pediatrics rates it as compatible with Breastfeeding.

Caffeine while Breastfeeding

Low Risk

CAS Number: 58-08-2

Trimethylxanthine component which is present in many compounds like decongestant or pain relief drugs (50 to 100 mg per unit) . It is also present in many infusion beverages (coffee, tea, mate, guarana) and other drinks with allegedly energizing properties. See also Coffee, Caffeine (beverages). At a dose higher than 300 mg a-day may induce nervousness and irritability in the infant. Intravenous high doses used to treat post-epidural anesthesia headache within 2-3 days after delivery, before mature breast milk comes, are compatible with breastfeeding. High doses used Intravenously to treat headache related to epidural should be regarded as compatible with breastfeeding only in the 2-3 days before milk comes in. Elimination period may last from few hours in adults, to 3-4 days in the newborn infant. American Academy of Pediatrics: Maternal Medication Usually Compatible With Breastfeeding.


Zebutal | Butalbital, Acetaminophen And Caffeine Capsule Breastfeeding Analsys - 2


Butalbital while Breastfeeding

CAS Number: 77-26-9

Because there is no published experience with butalbital or combination products containing butalbital during breastfeeding, other agents may be preferred, especially while nursing a newborn or preterm infant.

Acetaminophen while Breastfeeding

CAS Number: 103-90-2

Acetaminophen is a good choice for analgesia, and fever reduction in nursing mothers. Amounts in milk are much less than doses usually given to infants. Adverse effects in breastfed infants appear to be rare.

Caffeine while Breastfeeding

CAS Number: 58-08-2

Caffeine appears in breastmilk rapidly after maternal ingestion. Insufficient high-quality data are available to make good evidence-based recommendations on safe maternal caffeine consumption.[1] Fussiness, jitteriness and poor sleep patterns have been reported in the infants of mothers with very high caffeine intakes equivalent to about 10 or more cups of coffee daily. Studies in mothers taking 5 cups of coffee daily found no stimulation in breastfed infants 3 weeks of age and older. Some experts feel that a maternal intake limit of 300 mg daily might be a safe level of intake.[2] However, preterm and younger newborn infants metabolize caffeine very slowly and may have serum levels of caffeine and other active caffeine metabolites similar to their mothers' levels,[2][3][4] so a lower intake level preferable in the mothers of these infants. Other sources of caffeine, such as cola and energy drinks, yerba mate or guarana, will have similar dose-related effects on the breastfed infant. Coffee intake of more than 450 mL daily may decrease breastmilk iron concentrations and result in mild iron deficiency anemia in some breastfed infants.[5]



I am nursing mother and I have already used Zebutal | Butalbital, Acetaminophen And Caffeine Capsule, what should I do?

During whole lactation period you shall first discuss with your doctor and then together you shall decide whether you shall take that drug or not however if you have already taken Zebutal | Butalbital, Acetaminophen And Caffeine Capsule then you shall inform your doctor, But you should not be worried too much as Zebutal | Butalbital, Acetaminophen And Caffeine Capsule comes in category of low risk drug.


My health care provider has asked me to use Zebutal | Butalbital, Acetaminophen And Caffeine Capsule, what to do?

Though Zebutal | Butalbital, Acetaminophen And Caffeine Capsule dose not comes in category of safe drugs rather it comes in category of low risk but if your doctor is aware that you are breastfeeding your baby and has still recommended it then its advantages must be outweighing the risks.


If I am using Zebutal | Butalbital, Acetaminophen And Caffeine Capsule, will my baby need extra monitoring?

Not much


Who can I talk to if I have questions about usage of Zebutal | Butalbital, Acetaminophen And Caffeine Capsule in breastfeeding?

US
National Womens Health and Breastfeeding Helpline: 800-994-9662 (TDD 888-220-5446) 9 a.m. and 6 p.m. ET, Monday through Friday

UK
National Breastfeeding Helpline: 0300-100-0212 9.30am to 9.30pm, daily
Association of Breastfeeding Mothers: 0300-330-5453
La Leche League: 0345-120-2918
The Breastfeeding Network supporter line in Bengali and Sylheti: 0300-456-2421
National Childbirth Trust (NCT): 0300-330-0700

Australia
National Breastfeeding Helpline: 1800-686-268 24 hours a day, 7 days a week

Canada
Telehealth Ontario for breastfeeding: 1-866-797-0000 24 hours a day, 7 days a week

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