Cortenema | Hydrocortisone Enema while Breastfeeding

What is Cortenema | Hydrocortisone Enema used for?

Cortenema | Hydrocortisone Enema while breastfeeding safe or not? Can there be any side effects for infant while using it during breastfeeding?

Hydrocortisone while Breastfeeding

CAS Number: 50-23-7

Cortisol is a normal component of breast milk. Although unlikely to achieve harmful levels for the infant, it is preferred the use of an alternative (Methylprednisolone, Prednisolone, Prednisone). Intra-articular administration of depot prednisone derivatives may be a cause of transient decrease of milk production. Eleventh WHO Model List of Essential Drugs 2002: Compatible with breastfeeding.

Hydrocortisone while Breastfeeding

CAS Number: 50-23-7

Hydrocortisone (cortisol) is a normal component of breastmilk that passes from the mother's bloodstream into milk and might have a role in intestinal maturation, the intestinal microbiome, growth, body composition or neurodevelopment, but adequate studies are lacking.[1] Concentrations follow a diurnal rhythm, with the highest concentrations in the morning at about 7:00 am and the lowest concentrations in the late afternoon and evening.[2][3] Cortisol in milk may protect against later infant obesity, especially in girls.[4] Hydrocortisone has not been studied in breastmilk after exogenous administration in pharmacologic amounts. Hydrocortisone in breastmilk is stable at room temperature and during repeated freeze-thaw cycles.[5] Although it is unlikely that dangerous amounts of hydrocortisone would reach the infant, a better studied alternate corticosteroid might be preferred. Maternal use of hydrocortisone as an enema would not be expected to cause any adverse effects in breastfed infants. Local maternal injections, such as for tendinitis, would not be expected to cause any adverse effects in breastfed infants, but might occasionally cause temporary loss of milk supply. See also Hydrocortisone, Topical. Hydrocortisone concentrations in breastmilk are not affected by storage for 36 hours at room temperature, during multiple freeze-thaw cycles, nor Holder pasteurization (62.5 degrees C for 30 minutes).[5][6]

What should I do if I am breastfeeding mother and I am already exposed to Cortenema | Hydrocortisone Enema?

I am nursing mother and my doctor has suggested me to use Cortenema | Hydrocortisone Enema, is it safe?

If I am using Cortenema | Hydrocortisone Enema, will my baby need extra monitoring?

Who can I talk to if I have questions about usage of Cortenema | Hydrocortisone Enema in breastfeeding?