

CAS Number: 58581-89-8
Second generation anti-histaminic drug with low sedative effect. Used for ophthalmic and nasal topical administration. On last update no relevant published data related to breastfeeding were found. A small dose together with a low plama level of most nasal and ophthalmologic compounds make that a significant excretion into breast milk would be unlikely.
CAS Number: 90566-53-3
At latest update no relevant data on this subject were found in connection with breastfeeding, however, its low systemic absorption rate with a high plasma protein-binding capacity makes that excretion into breast milk may be very unlikely. Experts on this field consider topical, oral or inhaled steroids compatible with breastfeeding. At usual dose of oral, inhaled (nasal or pulmonary) or dermatologic preparations are used, absorption is very low with non-significant levels achieved in plasma serum. Whenever a treatment for eczema or dermatitis of the nipple is required, the least potent preparation should be used. Apply after a breast feed to let it to disappear before the next feed. Clear out excess of cream with a gauze when indicated. Avoid continuous use for longer than a week. Steroid toxicity has occurred in an infant after continuous use of steroidal cream on the nipple. Avoid use of creams, gels and other topical medication containing paraffin (petroleum-derived mineral oil) in order to avoid the risk of absorption by the child.
CAS Number: 58581-89-8

Small occasional doses of azelastine nasal spray would not be expected to cause any adverse effects in breastfed infants. Larger doses or more prolonged use of the nasal spray may cause drowsiness and other effects in the infant or decrease the milk supply, particularly in combination with a sympathomimetic such as pseudoephedrine or before lactation is well established. Infant rejection of the breast might occur because of the bitter taste of the drug. The oral, nonsedating antihistamines are preferred alternatives. Because absorption from the eye is limited, azelastine would not be expected to cause any adverse effects in breastfed infants. To substantially diminish the amount of drug that reaches the breastmilk after using eye drops, place pressure over the tear duct by the corner of the eye for 1 minute or more, then remove the excess solution with an absorbent tissue.
CAS Number: 90566-53-3
Topical fluticasone has not been studied during breastfeeding. Since only extensive application of the most potent corticosteroids may cause systemic effects in the mother, it is unlikely that short-term application of topical corticosteroids would pose a risk to the breastfed infant by passage into breastmilk. However, it would be prudent to use the least potent drug on the smallest area of skin possible. It is particularly important to ensure that the infant's skin does not come into direct contact with the areas of skin that have been treated. Only the lower potency corticosteroids should be used on the nipple or areola where the infant could directly ingest the drugs from the skin. Only water-miscible cream or gel products should be applied to the breast because ointments may expose the infant to high levels of mineral paraffins via licking.[1] Any topical corticosteroid should be wiped off thoroughly prior to nursing if it is being applied to the breast or nipple area.

Dymista | Azelastine Hydrochloride And Fluticasone Propionate Spray, Metered is in the category of low risk, if you have already used it then its not a big deal if health and behavior of baby is good. However your health care provider shall be aware of the fact that you have used Dymista | Azelastine Hydrochloride And Fluticasone Propionate Spray, Metered so you should inform him based on your convenience.
Dymista | Azelastine Hydrochloride And Fluticasone Propionate Spray, Metered comes in category of low risk and if your doctor is aware that you are breastfeeding it should be ok to use
Not much monitoring required while using Dymista | Azelastine Hydrochloride And Fluticasone Propionate Spray, Metered
US
National Womens Health and Breastfeeding Helpline: 800-994-9662 (TDD 888-220-5446) 9 a.m. and 6 p.m. ET, Monday through Friday
UK
National Breastfeeding Helpline: 0300-100-0212 9.30am to 9.30pm, daily
Association of Breastfeeding Mothers: 0300-330-5453
La Leche League: 0345-120-2918
The Breastfeeding Network supporter line in Bengali and Sylheti: 0300-456-2421
National Childbirth Trust (NCT): 0300-330-0700
Australia
National Breastfeeding Helpline: 1800-686-268 24 hours a day, 7 days a week
Canada
Telehealth Ontario for breastfeeding: 1-866-797-0000 24 hours a day, 7 days a week