Itraconazole Solution while Breastfeeding
American Academy of Pediatrics and other medical experts exclusively recommend to breastfeed the baby for first 6 months. Once you introduce baby to other foods it is recommended to breastfeed for at least first year of babys life. Taking medication while breastfeeding could be tricky as most drugs pass in breast milk. In this article we will evaluate Itraconazole Solution for its safety in breastfeeding.

What is Itraconazole Solution used for?


Itraconazole Oral Solution is indicated for the treatment of oropharyngeal and esophageal candidiasis. (See CLINICAL PHARMACOLOGY: Special Populations, WARNINGS, and ADVERSE REACTIONS: Post-marketing Experience for more information.)

Is Itraconazole Solution usage safe while breastfeeding? If a lactating mother is using it can there be any effect on growth or development of infant?

Itraconazole Solution safe for breastfeeding
Active ingredient in Itraconazole Solution is Itraconazole and based on our analysis of Itraconazole it appears that using Itraconazole Solution is safe in breastfeeding. Below is analysis of Itraconazole while breastfeeding.

Statement of Manufacturer/Labeler about breastfeeding usage
Nursing Mothers Itraconazole is excreted in human milk; therefore, the expected benefits of Itraconazole Oral Solution therapy for the mother should be weighed against the potential risk from exposure of itraconazole to the infant. The U.S. Public Health Service Centers for Disease Control and Prevention advises HIV-infected women not to breast-feed to avoid potential transmission of HIV to uninfected infants.

Itraconazole Solution Breastfeeding Analsys


Itraconazole while Breastfeeding

Safe

CAS Number: 84625-61-6

Pharmacokinetic data (moderately high molecular weight and high protein binding capacity) explain its nil or negligible amount observed in breast milk (McNamara, 2004), such that a breastfed infant would receive a maximum of 35 micrograms per day of Itraconazole, amount which is a hundred times lower than the pediatric dose of 5 mg / kg / day currently recommended (Janssen Cazzaniga 2014 and 1996) Both, low oral bioavailability and alkaline pH hinder its absorption from ingested milk. It is used to treat fungal infections in children, including premature babies, with a good tolerance. Itraconazole significantly increases plasma concentrations of Domperidone, which must be taken into account in case of simultaneous administration of both drugs.

Itraconazole Solution Breastfeeding Analsys - 2


Itraconazole while Breastfeeding

CAS Number: 84625-61-6

No information is available on the clinical use of itraconazole during breastfeeding. However, limited data indicate that maternal itraconazole produces levels in milk that are less than the 5 mg/kg daily doses that have been recommended to treat infants. Until more data become available, an alternate drug may be preferred, especially while nursing a newborn or preterm infant.


I already used Itraconazole Solution and meanwhile I breastfed my baby should I be concerned?

It is always a good idea to keep your healthcare provider or doctor informed about your drug usage during pregnancy and breastfeeding but if you have not informed your doctor about Itraconazole Solution and have used it then do not panic as Itraconazole Solution is mostly safe in breastfeeding and should not cause any harm to your baby.


I am nursing mother and my doctor has suggested me to use Itraconazole Solution, is it safe?

Definitely, Itraconazole Solution is safe in lactation for baby. No wonder your doctor has recommended it.


If I am using Itraconazole Solution, will my baby need extra monitoring?

No extra baby monitoring required while mother is using Itraconazole Solution


Who can I talk to if I have questions about usage of Itraconazole Solution in breastfeeding?

US
National Womens Health and Breastfeeding Helpline: 800-994-9662 (TDD 888-220-5446) 9 a.m. and 6 p.m. ET, Monday through Friday

UK
National Breastfeeding Helpline: 0300-100-0212 9.30am to 9.30pm, daily
Association of Breastfeeding Mothers: 0300-330-5453
La Leche League: 0345-120-2918
The Breastfeeding Network supporter line in Bengali and Sylheti: 0300-456-2421
National Childbirth Trust (NCT): 0300-330-0700

Australia
National Breastfeeding Helpline: 1800-686-268 24 hours a day, 7 days a week

Canada
Telehealth Ontario for breastfeeding: 1-866-797-0000 24 hours a day, 7 days a week

Drug Brands with same Active ingredients

Sporanox | Itraconazole Solution
Tolsura | Itraconazole Capsule, Gelatin Coated