Leader | Glycerin, Petrolatum, Phenylephrine Hydrochloride And Pramoxine Hydrochloride Cream while Breastfeeding

What is Leader | Glycerin, Petrolatum, Phenylephrine Hydrochloride And Pramoxine Hydrochloride Cream ?

Can I use Leader | Glycerin, Petrolatum, Phenylephrine Hydrochloride And Pramoxine Hydrochloride Cream while breastfeeding?

Glycerin while Breastfeeding

CAS Number: 56-81-5

Glycerin or glycerol is a normal component of human tissues. Involved in lipid and galactose synthesis which is metabolized to glucose or glycogen.It is found naturally in breast milk, with a highest concentration in colostrum. When it is used rectally as a laxative, has little or no absorption. It has been used in preterm infants. The oral or intravenous administration is rarely used (extracellular edema, intracranial hypertension, diagnosis of Meniere's disease). A short half-life span makes it compatible with breastfeeding in these rare cases.It also compatible with intraocular administration. It has been used in creams and gels to treat pain and cracks of nipple during lactation without clear results on effectiveness. In those cases it should be cleaned thoroughly with water before the next breast suckling to prevent it could be swallowed by the infant, since a high intestinal absorption may induce an increased plasma osmolality that can result in dehydration of the infant.

Petrolatum while Breastfeeding

CAS Number: 8012-95-1

Mineral oil, paraffin or petroleum jelly is a saturated hydrocarbon derived from petroleum. The length of molecular chain may range from 15 to 40 carbons with a molecular weight between 200 and 600 daltons.It is used as a laxative, also in cosmetics, as emollient and as excipient in topical products for the skin. LAXATIVE: Mineral oils with more than 34 carbons (480 daltons) are not absorbed, or, only have minimal absorption through the intestine being this a reason for which those are that should be used on humans (Hagemann 1998). Infant daily intake should be nil or less than 4 mg / kg. For oils with less than 25 carbons daily intake should not exceed 0.2 mg / kg.When used as a laxative it has been suggested, (Mahadevan 2006), although weakly evidence based, that it may interfere with the absorption of liposoluble vitamins (Gattuso 1994).Infants whose mothers received this treatment did not suffer any change on their usual bowel movements (Baldwin 1963). COSMETICS as lotions and creams (body, hands or breast) and lipsticks are a source to accumulation of saturated hydrocarbons in body fat tissue (Concin 2011). Paraffin-containing breast creams significantly increase paraffin concentration in breastmilk (Noti 2003, Concin 2008) which is a reason to be avoided as they may increase the infant's daily intake to 40 mg / kg (Noti 2003). During breastfeeding it should be wise to avoid the use of paraffin-containing creams and/or having them restricted to a minimum, not to apply them on the breast or only at least as possible when they are part of the excipient of an important topical treatment provided residual traces are been thoroughly removed before the next feeding at the breast. The use of mineral oil as a laxative should be replaced by other less risky product. Local injection of paraffin for allegedly aesthetic purposes (breast augmentation or others) is a common practice in Eastern and Southeastern Asia, has often serious complications (Alagaratnam 1996, Zekri 1996, Ho 2001, Markopoulos 2006) which is a practice pending of eradication (Di Benedetto 2002). Although published data on it is lacking, it is presumed that paraffin concentrations in breastmilk would be greatly increased in these cases.

Phenylephrine hydrochloride while Breastfeeding

CAS Number: 59-42-7

Used on topical decongestant solutions for nose drops at low concentration. 10% midriatic eye drops are available. Because low concentration is used on nose and ophtalmic drops a significant excretion into breast milk is unlikely. Low oral biodisponibility minimizes any risk of harmful effect in the infant. Authorized for nasal or ophtalmic use on children aged younger than 1 year. Although on latest update relevant data on breastfeeding was not found it is considered to be safe when minimal dose is used. Avoid excessive or long term use. A related drug Pseudoephedrine can inhibit milk production. It would be advisable to press on the lachrimal sac to minimize absorption.

Pramoxine hydrochloride while Breastfeeding

CAS Number: 140-65-8

Anesthetic drugs for topical use, both dermatological and odontological, have almost nil absorption when properly used. Do not apply on the breast. Otherwise, do it after having nursed, and cleanse it thoroughly with water before next feeding.

Phenylephrine hydrochloride while Breastfeeding

CAS Number: 59-42-7

The oral bioavailability of phenylephrine is only about 40%,[1] so the drug is unlikely to reach the infant in large amounts. However, intravenous or oral administration of phenylephrine might decrease milk production. Because no information is available on the use of oral phenylephrine during breastfeeding, an alternate drug may be preferred, especially while nursing a newborn or preterm infant.Phenylephrine nasal spray or ophthalmic drops are less likely to decrease lactation. To substantially diminish the effect of the drug after using eye drops, place pressure over the tear duct by the corner of the eye for 1 minute or more, then remove the excess solution with an absorbent tissue.

What should I do if already breastfed my kid after using Leader | Glycerin, Petrolatum, Phenylephrine Hydrochloride And Pramoxine Hydrochloride Cream?

My doctor has prescribed me Leader | Glycerin, Petrolatum, Phenylephrine Hydrochloride And Pramoxine Hydrochloride Cream, what should I do?

If I am using Leader | Glycerin, Petrolatum, Phenylephrine Hydrochloride And Pramoxine Hydrochloride Cream, will my baby need extra monitoring?

Who can I talk to if I have questions about usage of Leader | Glycerin, Petrolatum, Phenylephrine Hydrochloride And Pramoxine Hydrochloride Cream in breastfeeding?