Fasenra | Benralizumab Injection Breastfeeding
Nutrients from the food that you eat passes to your breast milk. Its good idea to take healthy diet while breastfeeding. You may need to consume more calories per day to support healthy body system. Some time it gets necessary take medicine while you are breastfeeding and as other food items passes into breast milk, medicine passes as well hence it becomes obvious to understand its effects while breastfeeding. We have analyzed many medications and in this sheet we will present some fact and known information associated with Fasenra | Benralizumab Injection while breast-feeding.

What is Fasenra | Benralizumab Injection used for?


FASENRA is indicated for the add-on maintenance treatment of patients with severe asthma aged 12 years and older, and with an eosinophilic phenotype [see Clinical Studies (14)]. Limitations of use: •FASENRA is not indicated for treatment of other eosinophilic conditions. •FASENRA is not indicated for the relief of acute bronchospasm or status asthmaticus. FASENRA is an interleukin-5 receptor alpha-directed cytolytic monoclonal antibody (IgG1, kappa) indicated for the add-on maintenance treatment of patients with severe asthma aged 12 years and older, and with an eosinophilic phenotype. (1) Limitations of Use: •Not for treatment of other eosinophilic conditions. (1) •Not for relief of acute bronchospasm or status asthmaticus. (1)

Fasenra | Benralizumab Injection while breastfeeding safe or not? Can there be any side effects for infant while using it during breastfeeding?

Fasenra | Benralizumab Injection contains Benralizumab as active ingredients, . We do not have safety rating of Benralizumab but we do have analysis of Benralizumab, which is used in manufacturing of Fasenra | Benralizumab Injection. You can get a good idea about Fasenra | Benralizumab Injection usage while breastfeeding by going through our detailed analysis as below.

Fasenra | Benralizumab Injection Breastfeeding Analsys


Benralizumab while Breastfeeding

CAS Number: 1044511-01-4

No information is available on the clinical use of benralizumab during breastfeeding. Because benralizumab is a large protein molecule with a molecular weight of about 150,000, the amount in milk is likely to be very low and absorption is unlikely because it is probably destroyed in the infant's gastrointestinal tract. Until more data become available, benralizumab should be used with caution during breastfeeding, especially while nursing a newborn or preterm infant. Benralizumab is a human immunoglobulin G1 (IgG1) kappa antibody. Holder pasteurization (62.5 degrees C for 30 minutes) decreases the concentration of endogenous immunoglobulin G by up to 79%.[1][2] A study of 67 colostrum samples that underwent Holder pasteurization found that IgG amounts decreased by 34 to 40%. Specific IgG subclasses decreased by different amounts, with IgG1 activity decreasing by about 37%.[3] None of the studies measured IgG activity.

Is Fasenra | Benralizumab Injection safe while breastfeeding

I am nursing mother and I have already used Fasenra | Benralizumab Injection, what should I do?

We are not completely sure about safety of Fasenra | Benralizumab Injection in breastfeeding. We would suggest you to contact your doctor or health care provider and explain your situation with Fasenra | Benralizumab Injection. If you observe anything abnormal with your baby please call 911 or contact emergency services in your area.


I am nursing mother and my doctor has suggested me to use Fasenra | Benralizumab Injection, is it safe?

If your doctor considers Fasenra | Benralizumab Injection safe enough to prescribe for you that means its benefits outweigh its known risks.


If I am using Fasenra | Benralizumab Injection, will my baby need extra monitoring?

Not Sure, Please check with your doctor or lactation consultant.


Who can I talk to if I have questions about usage of Fasenra | Benralizumab Injection in breastfeeding?

US
National Womens Health and Breastfeeding Helpline: 800-994-9662 (TDD 888-220-5446) 9 a.m. and 6 p.m. ET, Monday through Friday

UK
National Breastfeeding Helpline: 0300-100-0212 9.30am to 9.30pm, daily
Association of Breastfeeding Mothers: 0300-330-5453
La Leche League: 0345-120-2918
The Breastfeeding Network supporter line in Bengali and Sylheti: 0300-456-2421
National Childbirth Trust (NCT): 0300-330-0700

Australia
National Breastfeeding Helpline: 1800-686-268 24 hours a day, 7 days a week

Canada
Telehealth Ontario for breastfeeding: 1-866-797-0000 24 hours a day, 7 days a week