Trisenox | Arsenic Trioxide Injection Breastfeeding
There are high number of clear evidence that breastfeeding provides best nutrition that you can give to your baby. It is also evident that lactation is good for mothers health as well. Evolution has designed breastfeeding in a way that it caters all nutritional need of your child. However modern medicine is quite new for evolution, that is why mothers body is not well prepared to filter unnecessary chemical found in medicines. It becomes a necessity to figure out which drug is safe and which drug is dangerous for your newborn while nursing. In this article we will understand function of Trisenox | Arsenic Trioxide Injection and its suitability with breastfeeding.

What is Trisenox | Arsenic Trioxide Injection used for?


TRISENOX is an arsenical indicated: In combination with tretinoin for treatment of adults with newly-diagnosed low-risk acute promyelocytic leukemia (APL) whose APL is characterized by the presence of the t(15;17) translocation or PML/RAR-alpha gene expression. (1.1) For induction of remission and consolidation in patients with APL who are refractory to, or have relapsed from, retinoid and anthracycline chemotherapy, and whose APL is characterized by the presence of the t(15;17) translocation or PML/RAR-alpha gene expression. (1.2) 1.1 Newly-Diagnosed Low-Risk APL TRISENOX is indicated in combination with tretinoin for treatment of adults with newly-diagnosed low-risk acute promyelocytic leukemia (APL) whose APL is characterized by the presence of the t(15;17) translocation or PML/RAR-alpha gene expression. 1.2 Relapsed or Refractory APL TRISENOX is indicated for induction of remission and consolidation in patients with APL who are refractory to, or have relapsed from, retinoid and anthracycline chemotherapy, and whose APL is characterized by the presence of the t(15;17) translocation or PML/RAR-alpha gene expression.

What are the risk associated with Trisenox | Arsenic Trioxide Injection usage while breastfeeding? What precautions shall I take while using it in breastfeeding?

Trisenox | Arsenic Trioxide Injection dangerous while breastfeeding
Our analysis of Arsenic trioxide which are active ingredients in Trisenox | Arsenic Trioxide Injection indicates that Trisenox | Arsenic Trioxide Injection is dangerous to use in breastfeeding. We strongly recommend you to go through detailed analysis of Arsenic trioxide as below and do not use Trisenox | Arsenic Trioxide Injection during breastfeeding.

Statement of Manufacturer/Labeler about breastfeeding usage
8.3 Females and Males of Reproductive Potential Pregnancy Testing TRISENOX can cause fetal harm when administered to a pregnant woman. Conduct pregnancy testing in females of reproductive potential prior to initiation of treatment with TRISENOX [see Use in Specific Populations (8.1)]. Contraception Females Advise females of reproductive potential to use effective contraception during and after treatment with TRISENOX and for six months after the final dose. Males Advise males with female sexual partners of reproductive potential to use effective contraception during and after treatment with TRISENOX and for three months after the final dose. Infertility Males Based on testicular toxicities including decreased testicular weight and impaired spermatogenesis observed in animal studies, TRISENOX may impair fertility in males of reproductive potential [see Nonclinical Toxicology (13.1)].

Trisenox | Arsenic Trioxide Injection Breastfeeding Analsys


Arsenic trioxide while Breastfeeding

Dangerous

Used in the treatment of promyelocitic leukemia in adults.

Trisenox | Arsenic Trioxide Injection Breastfeeding Analsys - 2


Arsenic trioxide while Breastfeeding

CAS Number: 1327-53-3

Most sources consider breastfeeding to be contraindicated during maternal antineoplastic drug therapy. It might be possible to breastfeed safely during intermittent therapy with an appropriate period of breastfeeding abstinence; the manufacturer recommends an abstinence period of 1 week after the last dose. Chemotherapy may adversely affect the normal microbiome and chemical makeup of breastmilk.[1] Women who receive chemotherapy during pregnancy are more likely to have difficulty nursing their infant.[2]

Trisenox | Arsenic Trioxide Injection and breastfeeding

What should I do if I am breastfeeding mother and I am already exposed to Trisenox | Arsenic Trioxide Injection?

You should immediately inform your health care provider about Trisenox | Arsenic Trioxide Injection usage and your breastfeeding interval after usage of . If you feel baby is having abnormal behavior or any other health issue please call 911 immediately or contact nearest medical emergency center.


I am nursing mother and my doctor has suggested me to use Trisenox | Arsenic Trioxide Injection, is it safe?

Please double check with your doctor if he is aware of your breastfeeding stratus, Ask your doctor if there is any safe alternative of Trisenox | Arsenic Trioxide Injection. Check with your doctor if you shall temporally stop breastfeeding. You may go for second opinion as well. Still after all of this if your doctor still recommends Trisenox | Arsenic Trioxide Injection then go for it as they have access on more detailed medical and scientific information and they understand your individual medical situation much better.


If I am using Trisenox | Arsenic Trioxide Injection, will my baby need extra monitoring?

Extreme level of monitoring required as Trisenox | Arsenic Trioxide Injection could be dangerous for kid.


Who can I talk to if I have questions about usage of Trisenox | Arsenic Trioxide Injection in breastfeeding?

US
National Womens Health and Breastfeeding Helpline: 800-994-9662 (TDD 888-220-5446) 9 a.m. and 6 p.m. ET, Monday through Friday

UK
National Breastfeeding Helpline: 0300-100-0212 9.30am to 9.30pm, daily
Association of Breastfeeding Mothers: 0300-330-5453
La Leche League: 0345-120-2918
The Breastfeeding Network supporter line in Bengali and Sylheti: 0300-456-2421
National Childbirth Trust (NCT): 0300-330-0700

Australia
National Breastfeeding Helpline: 1800-686-268 24 hours a day, 7 days a week

Canada
Telehealth Ontario for breastfeeding: 1-866-797-0000 24 hours a day, 7 days a week

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