Ipratropium Bromide Solution Breastfeeding

American Academy of Pediatrics and other medical experts exclusively recommend to breastfeed the baby for first 6 months. Once you introduce baby to other foods it is recommended to breastfeed for at least first year of babys life. Taking medication while breastfeeding could be tricky as most drugs pass in breast milk. In this article we will evaluate Ipratropium Bromide Solution for its safety in breastfeeding.

What is Ipratropium Bromide Solution used for?


Ipratropium Bromide Inhalation Solution administered either alone or with other bronchodilators, especially beta adrenergics, is indicated as a bronchodilator for maintenance treatment of bronchospasm associated with chronic obstructive pulmonary disease, including chronic bronchitis and emphysema.

I am breastfeeding mother and I am using Ipratropium Bromide Solution. Can it have any bad effect on my kid? Shall I search for better alternative?

Ipratropium Bromide Solution safe for breastfeeding
Active ingredient in Ipratropium Bromide Solution is Ipratropium bromide anhydrous and based on our analysis of Ipratropium bromide anhydrous it appears that using Ipratropium Bromide Solution is safe in breastfeeding. Below is analysis of Ipratropium bromide anhydrous while breastfeeding.

Statement of Manufacturer/Labeler about breastfeeding usage
NURSING MOTHERS It is not known whether ipratropium bromide is excreted in human milk. Although lipid-insoluble quaternary bases pass into breast milk, it is unlikely that ipratropium bromide would reach the infant to a significant extent, especially when taken by inhalation since ipratropium bromide is not well absorbed systemically after inhalation or oral administration. However, because many drugs are excreted in human milk, caution should be exercised when ipratropium bromide is administered to a nursing woman.

Ipratropium Bromide Solution Breastfeeding Analsys


Ipratropium bromide anhydrous while Breastfeeding

Safe

CAS Number: 22254-24-6

At latest update no published data on excretion into breastmilk were found.

 Because of a large volume of distribution along with a very low or undetectable plasma concentration reached after inhalation (Laurikainen 1988, Wood 1995), it must be very unlikely the passage of significant amounts into breastmilk.
Its low oral bioavailability would hamper the pass to the infant’s plasma through the breastmilk ingested.
It has been used to treat newborns (Pediamecum 2015). 

Experts and scientific societies consider the use of ipratropium bromide during breastfeeding as devoid of risk to the infant (van Haren 1998, National Asthma Education 2004, Amir 2011).

Ipratropium Bromide Solution Breastfeeding Analsys - 2


Ipratropium bromide anhydrous while Breastfeeding

CAS Number: 60205-81-4

Although no published data exist on the use of ipratropium, its use produces negligible maternal serum levels and any drug in breastmilk would not be absorbed by the infant. The risk to the breastfed infant of maternal ipratropium inhalation is small.

Ipratropium Bromide Solution and breastfeeding

I already used Ipratropium Bromide Solution and meanwhile I breastfed my baby should I be concerned?

As usage of Ipratropium Bromide Solution is mostly safe while breastfeeding hence there should not be any concern. In case of any change in behavior or health of your baby you should inform your health care provider about usage of Ipratropium Bromide Solution else no further action is required.


I am nursing mother and my doctor has suggested me to use Ipratropium Bromide Solution, is it safe?

Definitely, Ipratropium Bromide Solution is safe in lactation for baby. No wonder your doctor has recommended it.


If I am using Ipratropium Bromide Solution, will my baby need extra monitoring?

No extra baby monitoring required while mother is using Ipratropium Bromide Solution


Who can I talk to if I have questions about usage of Ipratropium Bromide Solution in breastfeeding?

US
National Womens Health and Breastfeeding Helpline: 800-994-9662 (TDD 888-220-5446) 9 a.m. and 6 p.m. ET, Monday through Friday

UK
National Breastfeeding Helpline: 0300-100-0212 9.30am to 9.30pm, daily
Association of Breastfeeding Mothers: 0300-330-5453
La Leche League: 0345-120-2918
The Breastfeeding Network supporter line in Bengali and Sylheti: 0300-456-2421
National Childbirth Trust (NCT): 0300-330-0700

Australia
National Breastfeeding Helpline: 1800-686-268 24 hours a day, 7 days a week

Canada
Telehealth Ontario for breastfeeding: 1-866-797-0000 24 hours a day, 7 days a week

Drug Brands with same Active ingredients

Ipratropium Bromide Spray, Metered
Atrovent Hfa | Ipratropium Bromide Aerosol, Metered