It is a well known fact that breastfeeding is best source of nutrition for infants. Breast milk provides minerals, vitamins and antibodies in most acceptable format when they need it. Nutrition taken by mother passes to breast-milk and same thing applies to medicines taken by mothers. Not all drugs cause problem for baby but some do. Lets analyze if Acunivive 60 | Ketorolac Tromethamine Injection is safe for baby while breastfed.
What is Acunivive 60 | Ketorolac Tromethamine Injection used for?
Carefully consider the potential benefits and risks of ketorolac tromethamine and other treatment options before deciding to use ketorolac. Use the lowest effective dose for the shortest duration consistent with individual patient treatment goals (see WARNINGS ). Acute Pain in Adult Patients Ketorolac tromethamine is indicated for the short-term (≤5 days) management of moderately severe acute pain that requires analgesia at the opioid level, usually in a postoperative setting. Therapy should always be initiated with IV or IM dosing of ketorolac tromethamine, and oral ketorolac tromethamine is to be used only as continuation treatment, if necessary. The total combined duration of use of ketorolac tromethamine injection, and oral ketorolac tromethamine is not to exceed 5 days of use because of the potential of increasing the frequency and severity of adverse reactions associated with the recommended doses (see WARNINGS, PRECAUTIONS, DOSAGE AND ADMINISTRATION , and ADVERSE REACTIONS ). Patients should be switched to alternative analgesics as soon as possible, but ketorolac tromethamine therapy is not to exceed 5 days (see DOSAGE AND ADMINISTRATION, Pharmaceutical Information for Ketorolac Tromethamine Injection).
Is using Acunivive 60 | Ketorolac Tromethamine Injection unsafe in breastfeeding? Can there be bad consequences for baby if I use it while breastfeeding?
Ketorolac tromethamine is the only one ingredient used in manufacturing of Acunivive 60 | Ketorolac Tromethamine Injection, Which makes it easier to analyze its effect in breastfeeding. As per our analysis of Ketorolac tromethamine it is safe to use Acunivive 60 | Ketorolac Tromethamine Injection while lactating. We suggest you to check further details below about Ketorolac tromethamine usage in breastfeeding.
Statement of Manufacturer/Labeler about breastfeeding usage
Nursing Mothers Limited data from one published study that included 10 breastfeeding women 2-6 days postpartum showed low levels of ketorolac in breast milk and were undetectable (less than 5 ng/mL) in 4 of the patients. After a single administration of 10 mg of ketorolac tromethamine, the maximum milk concentration observed was 7.3 ng/mL, and the maximum milk-to-plasma ratio was 0.037. After 1 day of dosing (10 mg every 6 hours), the maximum milk concentration was 7.9 ng/mL, and the maximum milk-to-plasma ratio was 0.025. Assuming a daily intake of 400 to 1,000 mL of human milk per day and a maternal body weight of 60 kg, the calculated maximum daily infant exposure was 0.00263 mg/kg/day, which is 0.4% of the maternal weight-adjusted dose. Exercise caution when ketorolac is administered to a nursing woman. Available information has not shown any specific adverse events in nursing infants; however, instruct patients to contact their infant's healthcare provider if they note any adverse events.
Acunivive 60 | Ketorolac Tromethamine Injection Breastfeeding Analsys
CAS Number: 74103-06-3
Excretion into breast milk is insignificant and safe for pediatric treatment. Since the possibility of harmful effects on the blood and kidney among treated patients is controversial (not through breast milk) high dosing would better be avoided within 21 days post delivery. Keratolac eye drops are very safe because a low content of drug. The American Academy of Pediatrics rates it usually compatible with breastfeeding.
Acunivive 60 | Ketorolac Tromethamine Injection Breastfeeding Analsys - 2
CAS Number: 74103-06-3
Limited data indicate that milk levels of ketorolac are low with the usual oral dosage, but milk levels have not been measured after higher injectable dosages. Use caution when using systemic ketorolac in nursing mothers, especially with the injectable drug. Maternal use of ketorolac eye drops would not be expected to cause any adverse effects in breastfed infants. To substantially diminish the amount of drug that reaches the breastmilk after using eye drops, place pressure over the tear duct by the corner of the eye for 1 minute or more, then remove the excess solution with an absorbent tissue.
What should I do if already breastfed my kid after using Acunivive 60 | Ketorolac Tromethamine Injection?
As usage of Acunivive 60 | Ketorolac Tromethamine Injection is mostly safe while breastfeeding hence there should not be any concern. In case of any change in behavior or health of your baby you should inform your health care provider about usage of Acunivive 60 | Ketorolac Tromethamine Injection else no further action is required.
My health care provider has asked me to use Acunivive 60 | Ketorolac Tromethamine Injection, what to do?
Definitely, Acunivive 60 | Ketorolac Tromethamine Injection is safe in lactation for baby. No wonder your doctor has recommended it.
If I am using Acunivive 60 | Ketorolac Tromethamine Injection, will my baby need extra monitoring?
No extra baby monitoring required while mother is using Acunivive 60 | Ketorolac Tromethamine Injection
Who can I talk to if I have questions about usage of Acunivive 60 | Ketorolac Tromethamine Injection in breastfeeding?
National Womens Health and Breastfeeding Helpline: 800-994-9662 (TDD 888-220-5446) 9 a.m. and 6 p.m. ET, Monday through Friday
National Breastfeeding Helpline: 0300-100-0212 9.30am to 9.30pm, daily
Association of Breastfeeding Mothers: 0300-330-5453
La Leche League: 0345-120-2918
The Breastfeeding Network supporter line in Bengali and Sylheti: 0300-456-2421
National Childbirth Trust (NCT): 0300-330-0700
National Breastfeeding Helpline: 1800-686-268 24 hours a day, 7 days a week
Telehealth Ontario for breastfeeding: 1-866-797-0000 24 hours a day, 7 days a week