Buprenorphine Hydrochloride Injection while Breastfeeding
What is Buprenorphine Hydrochloride Injection used for?
What are the risk associated with Buprenorphine Hydrochloride Injection usage while breastfeeding? What precautions shall I take while using it in breastfeeding?
Nursing Mothers: An apparent lack of milk production during general reproduction studies with buprenorphine in rats caused decreased viability and lactation indices. Use of high doses of sublingual buprenorphine in pregnant women showed that buprenorphine passes into the mother’s milk. Breast-feeding is therefore not advised in nursing mothers treated with buprenorphine.
Buprenorphine Hydrochloride Injection Breastfeeding Analsys
Buprenorphine while Breastfeeding
SafeCAS Number: 52485-79-7
It is a semi-synthetic opioid which is used to replace Methadone in the treatment of opioid addiction. Mothers on Buprenorphine showed a shorter mean hospital stay than those who were treated with Methadone. The amount of dose reaching the infant is minimal and has no untoward side effects. It has been noticed a mild and transient abstinence syndrome after birth when sudden withdrawn occurred. Addiction to narcotic drugs and the use of substitutive treatments lowers the breastfeeding rate and duration of nursing.
Buprenorphine Hydrochloride Injection Breastfeeding Analsys - 2
Buprenorphine while Breastfeeding
CAS Number: 52485-79-7
Because of the low levels of buprenorphine in breastmilk, its poor oral bioavailability in infants, and the low drug concentrations found in the serum and urine of breastfed infants, its use is acceptable in nursing mothers. Monitor the infant for drowsiness, respiratory depression, adequate weight gain, and developmental milestones, especially in younger, exclusively breastfed infants. Although unlikely, if the baby shows signs of increased sleepiness (more than usual), difficulty breastfeeding, breathing difficulties, or limpness, a physician should be contacted immediately. Observe infants for withdrawal signs if breastfeeding is stopped abruptly. Women who received buprenorphine for opiate abuse during pregnancy and are stable should be encouraged to breastfeed their infants postpartum, unless there is another contraindication, such as use of street drugs.[1][2][3][4][5][6][7][8][9][10] The long-term outcome of infants breastfed during maternal buprenorphine therapy for opiate abuse has not been well studied.[11] The breastfeeding rate among mothers taking buprenorphine for opiate dependency may be lower than in other mothers.
What should I do if already breastfed my kid after using Buprenorphine Hydrochloride Injection?
Buprenorphine Hydrochloride Injection is safe in breastfeeding and should not create any health problem for your baby but in case you feel any health issue associated with Buprenorphine Hydrochloride Injection you should contact your doctor or health care provider. Be it pregnancy or lactation you shall keep your doctor informed.
I am nursing mother and my doctor has suggested me to use Buprenorphine Hydrochloride Injection, is it safe?
Usage of Buprenorphine Hydrochloride Injection is safe for nursing mothers and baby, No worries.
If I am using Buprenorphine Hydrochloride Injection, will my baby need extra monitoring?
No
Who can I talk to if I have questions about usage of Buprenorphine Hydrochloride Injection in breastfeeding?
US
National Womens Health and Breastfeeding Helpline: 800-994-9662 (TDD 888-220-5446) 9 a.m. and 6 p.m. ET, Monday through Friday
UK
National Breastfeeding Helpline: 0300-100-0212 9.30am to 9.30pm, daily
Association of Breastfeeding Mothers: 0300-330-5453
La Leche League: 0345-120-2918
The Breastfeeding Network supporter line in Bengali and Sylheti: 0300-456-2421
National Childbirth Trust (NCT): 0300-330-0700
Australia
National Breastfeeding Helpline: 1800-686-268 24 hours a day, 7 days a week
Canada
Telehealth Ontario for breastfeeding: 1-866-797-0000 24 hours a day, 7 days a week