Exforge Hct | Amlodipine Valsartan And Hydrochlorothiazide Tablet while Breastfeeding

What is Exforge Hct | Amlodipine Valsartan And Hydrochlorothiazide Tablet used for?

Can I continue breastfeeding if I am using Exforge Hct | Amlodipine Valsartan And Hydrochlorothiazide Tablet? How long does it stays in breast milk?

Amlodipine while Breastfeeding

CAS Number: 111470-99-6

It is excreted into breast milk in small amount (less than 10% of relative dose) without problems observed in infants whose mothers were on treatment with this drug. (Naito 2015, Ahn 2007)When measured, the plasma levels of drug in these infants were undetectable (Vasa 2013). Because its drug elimination period is very prolonged, an alternative drug known to be safer should be used, especially during the neonatal period and in case of premature infant.

Valsartan while Breastfeeding

CAS Number: 137862-53-4

At latest update, relevant published data on excretion into breast milk were not found. A high protein-binding capacity makes excretion into breast milk unlikely. In addition, a low oral bioavailability makes difficult the absorption towards the infant's plasma from ingested milk, except in prematures or newborns who may show an increased absorption. Case report of kidney function impairment of a baby whose mother had taken Telmisartan in pregnancy. Until more data on this medication is available, safer alternative drugs are preferred, especially in premature babies or during the neonatal period. Should an ARA-II medication (Sartan type) be necessary, the associated risk may be decreased by choosing the one with a favorable pharmacokinetics (shorter half-life elimination time and lower bioavailability) like Eprosartan and Losartan

Hydrochlorothiazide while Breastfeeding

CAS Number: 58-93-5

Thiazide diuretic drug. Excretion into breast milk is clinically non-significant. No side-effects were observed in a one-month old breastfed baby whose mother was treated with this medication. Drug level in the plasma of this child was undetectable. Long-term treatment with diuretic drugs (particularly Thiazide type ones with long-lasting effect and loop-acting mechanism) may inhibit lactation, mostly if lactation is not well-established yet. Use as lower dose as possible, especially during the first postnatal month. American Academy of Pediatrics 2013: Maternal Medication Usually Compatible With Breastfeeding. WHO Model List of Essential Drugs 2002: Compatible with breastfeeding.

Amlodipine while Breastfeeding

CAS Number: 88150-42-9

Limited information indicates that milk levels of amlodipine are usually low and plasma levels in breastfed infants are undetectable. Maternal use of amlodipine during breastfeeding has not caused any adverse effects in breastfed infants. If amlodipine is required by the mother, it is not a reason to discontinue breastfeeding.

Valsartan while Breastfeeding

CAS Number: 137862-53-4

Because no information is available on the use of valsartan during breastfeeding, an alternate drug may be preferred, especially while nursing a newborn or preterm infant.

Hydrochlorothiazide while Breastfeeding

CAS Number: 58-93-5

Hydrochlorothiazide doses of 50 mg daily or less are acceptable during lactation. Intense diuresis with large doses may decrease breastmilk production.

What should I do if I am breastfeeding mother and I am already exposed to Exforge Hct | Amlodipine Valsartan And Hydrochlorothiazide Tablet?

My doctor has prescribed me Exforge Hct | Amlodipine Valsartan And Hydrochlorothiazide Tablet, what should I do?

If I am using Exforge Hct | Amlodipine Valsartan And Hydrochlorothiazide Tablet, will my baby need extra monitoring?

Who can I talk to if I have questions about usage of Exforge Hct | Amlodipine Valsartan And Hydrochlorothiazide Tablet in breastfeeding?