Oxycodone Apap Tablet while Breastfeeding

What is Oxycodone Apap Tablet used for?

Is Oxycodone Apap Tablet usage safe while breastfeeding? If a lactating mother is using it can there be any effect on growth or development of infant?

Oxycodone hydrochloride while Breastfeeding

CAS Number: 76-42-6

Very often used for treatment of pain associated to episiotomy or Cesarean section operation. Excreted and accumulates into breast milk in significant amount along with associated problems among 20% of breastfed infants from treated mothers. Side effects have been rarely severe like excessive sedation, letargia, hypothermia and apnea. Dose should not be higher than 30 mg a day for no longer than 3 days. Women with some variants of enzyme-linked gene CYP2D6 who are on Oxycodone and their breastfed infants may experience increased sedation. Dose should not be higher than 30 mg a day for no longer than 3 days. Use of Oxycodone during childhood is risky because of a large elimination half-life variability. Adequately use of nonsteroidal anti-inflammatory drugs (NSAIDs) may attain pain relief with less side effects than with narcotic analgesics.

Acetaminophen while Breastfeeding

CAS Number: 103-90-2

Excreted in very low amount into breast milk. Infant intake may be lower than 4% of usual pediatric dose. The American Academy of Pediatrics rates it as compatible with Breastfeeding.

Oxycodone hydrochloride while Breastfeeding

CAS Number: 76-42-6

Maternal use of oral narcotics during breastfeeding can cause infant drowsiness, central nervous system depression and even death. Infant sedation is common and well documented with maternal use of oxycodone. Newborn infants seem to be particularly sensitive to the effects of even small dosages of narcotic analgesics. Once the mother's milk comes in, it is best to provide pain control with a nonnarcotic analgesic and limit maternal intake of oral oxycodone (and combinations) to a 2 to 3 days, especially in the outpatient setting.[1] A maximum oxycodone dosage of 30 mg daily is suggested, although some sources recommend avoiding oxycodone during breastfeeding.[2][3] Oxycodone elimination is decreased in young infants with much inter-individual variability. Monitor the infant closely for drowsiness, adequate weight gain, and developmental milestones, especially in younger, exclusively breastfed infants. If the baby shows signs of increased sleepiness (more than usual), difficulty breastfeeding, breathing difficulties, or limpness, a physician should be contacted immediately. Other agents are preferred over oxycodone during breastfeeding.[2]

Acetaminophen while Breastfeeding

CAS Number: 103-90-2

Acetaminophen is a good choice for analgesia, and fever reduction in nursing mothers. Amounts in milk are much less than doses usually given to infants. Adverse effects in breastfed infants appear to be rare.

What if I already have used Oxycodone Apap Tablet?

I am nursing mother and my doctor has suggested me to use Oxycodone Apap Tablet, is it safe?

If I am using Oxycodone Apap Tablet, will my baby need extra monitoring?

Who can I talk to if I have questions about usage of Oxycodone Apap Tablet in breastfeeding?