Glyburide Tablet Breastfeeding

Modern medicine has evolved so much so that sooner or later every breastfeeding mother needs to take it in one form or other. Medication that is present in mothers blood will transfer into her breast milk to some extent. Most drugs do so at low levels and pose no real risk to infants but then there are some exceptions. In This post will discuss whether Glyburide Tablet is safe in breast-feeding or not.

What is Glyburide Tablet used for?

Glyburide tablets, USP are indicated as an adjunct to diet and exercise to improve glycemic control in adults with type 2 diabetes mellitus.

Is Glyburide Tablet usage safe while breastfeeding? If a lactating mother is using it can there be any effect on growth or development of infant?

Glyburide Tablet safe for breastfeeding
Active ingredient in Glyburide Tablet is Glyburide and based on our analysis of Glyburide it appears that using Glyburide Tablet is safe in breastfeeding. Below is analysis of Glyburide while breastfeeding.

Statement of Manufacturer/Labeler about breastfeeding usage
Nursing Mothers Although it is not known whether glyburide is excreted in human milk, some sulfonylurea drugs are known to be excreted in human milk. Because the potential for hypoglycemia in nursing infants may exist, a decision should be made whether to discontinue nursing or to discontinue the drug, taking into account the importance of the drug to the mother. If the drug is discontinued, and if diet alone is inadequate for controlling blood glucose, insulin therapy should be considered.

Glyburide Tablet Breastfeeding Analsys

Glyburide while Breastfeeding


CAS Number: 10238-21-8

Sulfonylureas stimulate endogenous insulin secretion. They can cause hypoglycemia. Its pharmacokinetic data (moderately high molecular weight and very high percentage of plasma protein binding) explain the zero or negligible passage into breast milk observed (Serrano 2014, Glatstein 2009, Feig 2007and 2005). Although blood sugar levels were normal in an infant whose mother was taking glibencamide (Feig 2005), one author suggests monitoring for symptoms of hypoglycemia in the infant (Glatstein 2009). List of WHO essential medicines: compatible with breastfeeding (WHO / UNICEF 2002). Diet, exercise, and breastfeeding improve blood sugar levels.

Glyburide Tablet Breastfeeding Analsys - 2

Glyburide while Breastfeeding

CAS Number: 10238-21-8

Limited data indicate that the levels of glyburide in milk are negligible. Monitor breastfed infants for signs of hypoglycemia such as jitteriness, excessive sleepiness, poor feeding, seizures cyanosis, apnea, or hypothermia. If there is concern, monitoring of the breastfed infant's blood glucose is advisable during maternal therapy with hypoglycemic agents.[1][2]

Is Glyburide Tablet safe while breastfeeding

I am nursing mother and I have already used Glyburide Tablet, what should I do?

As usage of Glyburide Tablet is mostly safe while breastfeeding hence there should not be any concern. In case of any change in behavior or health of your baby you should inform your health care provider about usage of Glyburide Tablet else no further action is required.

I am nursing mother and my doctor has suggested me to use Glyburide Tablet, is it safe?

Definitely, Glyburide Tablet is safe in lactation for baby. No wonder your doctor has recommended it.

If I am using Glyburide Tablet, will my baby need extra monitoring?

No extra baby monitoring required while mother is using Glyburide Tablet

Who can I talk to if I have questions about usage of Glyburide Tablet in breastfeeding?

National Womens Health and Breastfeeding Helpline: 800-994-9662 (TDD 888-220-5446) 9 a.m. and 6 p.m. ET, Monday through Friday

National Breastfeeding Helpline: 0300-100-0212 9.30am to 9.30pm, daily
Association of Breastfeeding Mothers: 0300-330-5453
La Leche League: 0345-120-2918
The Breastfeeding Network supporter line in Bengali and Sylheti: 0300-456-2421
National Childbirth Trust (NCT): 0300-330-0700

National Breastfeeding Helpline: 1800-686-268 24 hours a day, 7 days a week

Telehealth Ontario for breastfeeding: 1-866-797-0000 24 hours a day, 7 days a week