Diphenhydramine Hydrochloride Injection while Breastfeeding

What is Diphenhydramine Hydrochloride Injection used for?

What are the risk associated with Diphenhydramine Hydrochloride Injection usage while breastfeeding? What precautions shall I take while using it in breastfeeding?

Diphenhydramine hydrochloride while Breastfeeding

CAS Number: 58-73-1

It is a first generation antihistamine drug (Ethanolamine) with a strong sedative effect. A high protein-binding capacity makes difficult an excretion into breast milk in significant amounts in accordance with old studies that had confirmed it. The absorption from ingested mother's milk to the infant's plasma is hampered by a low oral bioavailability. For both, the mother and the infant is safer the use of antihistamine medication with higher safety levels without sedative effect, especially when the child is a premature or younger than 1 month old. Neither a decrease of milk production nor alteration of Prolactin release have been shown with the use of this drug. When used while breastfeeding do it with the lower dose as possible and avoid a long-term use. Check up for feeding difficulty and somnolence in the infant. Bed-sharing with the infant is not recommended for parents who are on this medication.

Diphenhydramine hydrochloride while Breastfeeding

CAS Number: 58-73-1

Small, occasional doses of diphenhydramine would not be expected to cause any adverse effects in breastfed infants. Larger doses or more prolonged use may cause effects in the infant or decrease the milk supply, particularly in combination with a sympathomimetic such as pseudoephedrine or before lactation is well established. Single bedtime doses after the last feeding of the day may be adequate for many women and will minimize any effects of the drug. The nonsedating antihistamines are preferred alternatives.

What if I already have used Diphenhydramine Hydrochloride Injection?

I am nursing mother and my doctor has suggested me to use Diphenhydramine Hydrochloride Injection, is it safe?

If I am using Diphenhydramine Hydrochloride Injection, will my baby need extra monitoring?

Who can I talk to if I have questions about usage of Diphenhydramine Hydrochloride Injection in breastfeeding?