Escitalopram Oxalate Solution Breastfeeding

Most health expert recommend six month of exclusive breastfeeding but statics suggest that numbers are not good, almost 95% mothers start breastfeeding but this number drops to 40% in first three month and further it drops to 15% till fifth month. Sometime its due to need of medication usage. Because of these statics its important to provide good information on safety of drugs in breastfeeding so that it can be improved when possible. In this FAQ sheet we will discuss about exposure to Escitalopram Oxalate Solution while breastfeeding. We will also discuss about common side effects and warnings associated with Escitalopram Oxalate Solution.

What is Escitalopram Oxalate Solution used for?


1 INDICATIONS & USAGE Escitalopram oxalate oral solution is a selective serotonin reuptake inhibitor (SSRI) indicated for: • Acute and Maintenance Treatment of Major Depressive Disorder (MDD) in adults and adolescents aged 12 to 17 years (1.1) • Acute Treatment of Generalized Anxiety Disorder (GAD) in adults (1.2) 1.1 Major Depressive Disorder Escitalopram oxalate oral solution is indicated for the acute and maintenance treatment of major depressive disorder in adults and in adolescents 12 to 17 years of age [see Clinical Studies (14.1) ]. A major depressive episode (DSM-IV) implies a prominent and relatively persistent (nearly every day for at least 2 weeks) depressed or dysphoric mood that usually interferes with daily functioning, and includes at least five of the following nine symptoms: depressed mood, loss of interest in usual activities, significant change in weight and/or appetite, insomnia or hypersomnia, psychomotor agitation or retardation, increased fatigue, feelings of guilt or worthlessness, slowed thinking or impaired concentration, a suicide attempt or suicidal ideation. 1.2 Generalized Anxiety Disorder Escitalopram oxalate oral solution is indicated for the acute treatment of Generalized Anxiety Disorder (GAD) in adults [see Clinical Studies (14.2) ]. Generalized Anxiety Disorder (DSM-IV) is characterized by excessive anxiety and worry (apprehensive expectation) that is persistent for at least 6 months and which the person finds difficult to control. It must be associated with at least 3 of the following symptoms: restlessness or feeling keyed up or on edge, being easily fatigued, difficulty concentrating or mind going blank, irritability, muscle tension, and sleep disturbance.

I am breastfeeding mother and I am using Escitalopram Oxalate Solution. Can it have any bad effect on my kid? Shall I search for better alternative?

Escitalopram Oxalate Solution safe for breastfeeding
As per our analysis Escitalopram Oxalate Solution contains only one ingredient and that is Escitalopram. We have analyzed Escitalopram and it seems to be safe to use Escitalopram while breastfeeding, that means usage of Escitalopram Oxalate Solution shall be safe while breastfeeding. Below you can check more details of Escitalopram usage in breastfeeding. We recommend you to go through provided detailed analysis as below take decision accordingly.

Statement of Manufacturer/Labeler about breastfeeding usage
8.3 Nursing Mothers Escitalopram is excreted in human breast milk. Limited data from women taking 10 to 20 mg escitalopram showed that exclusively breast-fed infants receive approximately 3.9% of the maternal weight-adjusted dose of escitalopram and 1.7% of the maternal weight-adjusted dose of desmethylcitalopram. There were two reports of infants experiencing excessive somnolence, decreased feeding, and weight loss in association with breastfeeding from a racemic citalopram-treated mother; in one case, the infant was reported to recover completely upon discontinuation of racemic citalopram by its mother and, in the second case, no follow-up information was available. Caution should be exercised and breastfeeding infants should be observed for adverse reactions when escitalopram oxalate is administered to a nursing woman.

Escitalopram Oxalate Solution Breastfeeding Analsys


Escitalopram while Breastfeeding

Safe

CAS Number: 128196-01-0

S-Enantiomer of Citalopram that shares similar pharmacokinetics and properties with Citalopram. Excretion into breast milk is clinically non-significant. Serum levels of infants from breastfeeding mothers who were treated have been shown to be undetectable or very low. Overall, short or long-term harmful effect has not been reported among breastfed infants. Isolated cases of irritability and neonatal necrotizing enterocolitis after intrauterine exposure have appeared in medical literature contrasting with harmlessness reported by others. Galactorrhea associated or not to hyperprolactinemia, may appear. Women who are on antidepressant treatment in pregnancy are in need of special and intensive support for breastfeeding because of a high risk of early weaning.

Escitalopram Oxalate Solution Breastfeeding Analsys - 2


Escitalopram while Breastfeeding

CAS Number: 128196-01-0

Escitalopram is the -isomer of the antidepressant, citalopram. Limited information indicates that maternal doses of escitalopram up to 20 mg daily produce low levels in milk and would not be expected to cause any adverse effects in breastfed infants, especially if the infant is older than 2 months. One case of necrotizing enterocolitis was reported in an breastfed newborn whose mother was taking escitalopram during pregnancy and lactation, but causality was not established. A seizure-like event occurred in an infant who was also exposed to bupropion in milk. Other minor behavioral problems have also been reported. Monitor the infant for drowsiness, especially in younger, exclusively breastfed infants and when using combinations of psychotropic drugs. Mothers taking an SSRI during pregnancy and postpartum may have more difficulty breastfeeding, although this might be a reflection of their disease state.[1] These mothers may need additional breastfeeding support. Breastfed infants exposed to an SSRI during the third trimester of pregnancy have a lower risk of poor neonatal adaptation than formula-fed infants.


What should I do if already breastfed my kid after using Escitalopram Oxalate Solution?

It is always a good idea to keep your healthcare provider or doctor informed about your drug usage during pregnancy and breastfeeding but if you have not informed your doctor about Escitalopram Oxalate Solution and have used it then do not panic as Escitalopram Oxalate Solution is mostly safe in breastfeeding and should not cause any harm to your baby.


I am nursing mother and my doctor has suggested me to use Escitalopram Oxalate Solution, is it safe?

Usage of Escitalopram Oxalate Solution is safe for nursing mothers and baby, No worries.


If I am using Escitalopram Oxalate Solution, will my baby need extra monitoring?

No


Who can I talk to if I have questions about usage of Escitalopram Oxalate Solution in breastfeeding?

US
National Womens Health and Breastfeeding Helpline: 800-994-9662 (TDD 888-220-5446) 9 a.m. and 6 p.m. ET, Monday through Friday

UK
National Breastfeeding Helpline: 0300-100-0212 9.30am to 9.30pm, daily
Association of Breastfeeding Mothers: 0300-330-5453
La Leche League: 0345-120-2918
The Breastfeeding Network supporter line in Bengali and Sylheti: 0300-456-2421
National Childbirth Trust (NCT): 0300-330-0700

Australia
National Breastfeeding Helpline: 1800-686-268 24 hours a day, 7 days a week

Canada
Telehealth Ontario for breastfeeding: 1-866-797-0000 24 hours a day, 7 days a week

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