Hydraday | Octocrylene And Avobenzone Cream while Breastfeeding

There are 2 main ingredients of Hydraday | Octocrylene And Avobenzone Cream, Octocrylene and Avobenzone. One by one we have analyzed both Octocrylene and Avobenzone for its impact on breastfeeding and based on our analysis we can conclude that Hydraday | Octocrylene And Avobenzone Cream is safe to use in breastfeeding. We recommend you to check our analysis of Octocrylene and Avobenzone as below.

Octocrylene and Breastfeeding

Based on the current available safety data, octocrylene used as a UV filter in cosmetic products at a concentration of 10% can be considered as safe. There was no evidence of any endocrine disruption potential from experimental studies which demonstrated no adverse effects on reproductive (e.g. oestrus cycle, epididymal and testicular sperm parameters) and developmental parameters. Effects on thyroid reported in repeated toxicity studies conducted in rats at very high doses are species?specific and not relevant considering the doses at which octocrylene is used in human.

Four studies on the transdermal absorption of octocrylene are available in the scientific literature, and an additional study is available in ECHA summaries of safety data. Dermal absorption studies of octocrylene showed that most octocrylene concentrations are found in the stratum corneum and that very few quantities are found in the epidermis (0.4%) and in the receptor fluid (<0.05%). In vivo, a very recent study in human volunteers showed systemic exposure to octocrylene with maximal concentrations ranging from 2.9 to 7.8 ng/mL under indoor maximal use conditions. Octocrylene has been found at very low amounts in human milk, and some metabolites of octocrylene were primarily detected in urine of volunteers using sunscreen products.

No systemic effects were reported after dermal exposure to octocrylene in rabbits at very high dose (534 mg/kg bw/day) compared with those used in cosmetic products. After oral exposure, effects on liver and thyroid were reported in a study conducted in rats at high doses (340 and 1085 mg/kg bw/day in males). These effects were investigated in an additional mechanistic study which showed that effects on thyroid were indirect and due to hepatic enzyme induction potential of octocrylene in rats at very high oral doses.

Based on available animal data, octocrylene does not induce developmental or teratogenic effects. In an extended one?generation reproductive toxicity study, only rats treated with the highest dose of octocrylene via oral route showed a decrease in the number of implantation sites and consequently a low number of pups. This very high dose of 550 mg/kg bw/day cannot be considered to be relevant to the dermal use of octocrylene as a cosmetic ingredient. Moreover, no other effects on male and female fertility and reproductive parameters such as oestrus cycle, epididymal and testicular sperm parameters were observed in all groups tested. Regarding pups, no effects on sexual and neurodevelopmental parameters were observed.

Avobenzone and Breastfeeding

Not much study has been done on effects of topical usage of Avobenzone during breast feeding however it is known to penetrate the skin in very limited quantity. Its not very likely to have adverse effects in breastfed infants.

What should I do if I am breastfeeding mother and I am already exposed to Hydraday | Octocrylene And Avobenzone Cream?

My health care provider has asked me to use Hydraday | Octocrylene And Avobenzone Cream, what to do?

If I am using Hydraday | Octocrylene And Avobenzone Cream, will my baby need extra monitoring?

Who can I talk to if I have questions about usage of Hydraday | Octocrylene And Avobenzone Cream in breastfeeding?