Aripiprazole Solution while Breastfeeding
It is recommended to breastfeed exclusively for six months and then while introducing to other food sources extend it to twelve months. In this duration most mothers will need help of some sort of medication, It could be for short term like could and flue or it could be something chronic like Arthritis or Diabetes and here comes the question of safety of medication in use. In this post we will figure out what is Aripiprazole Solution and whether its safe to use Aripiprazole Solution while nursing or not.

What is Aripiprazole Solution used for?


Aripiprazole oral solution is indicated for the treatment of: Schizophrenia [see CLINICAL STUDIES (14.1)] Acute Treatment of Manic and Mixed Episodes associated with Bipolar I Disorder [see CLINICAL STUDIES (14.2)] Additional pediatric use information in patients ages 6 to 18 years is approved for Otsuka America Pharmaceutical, Inc.’s ABILIFY® (aripiprazole) product. However, due to Otsuka America Pharmaceutical, Inc.’s marketing exclusivity rights, this drug product is not labeled with that pediatric information. Aripiprazole is an atypical antipsychotic. The oral formulation is indicated for: Schizophrenia (14.1) Acute Treatment of Manic and Mixed Episodes associated with Bipolar I (14.2)

Is Aripiprazole Solution usage safe while breastfeeding? If a lactating mother is using it can there be any effect on growth or development of infant?

Aripiprazole Solution low risk for breastfeeding
Aripiprazole is the one and only active ingredient present in Aripiprazole Solution. Aripiprazole in itself is a low risk drug for lactation so it is easy to understand that Aripiprazole Solution also comes in category of Low Risk item while breastfeeding. Below is the summary of Aripiprazole in breastfeeding.

Statement of Manufacturer/Labeler about breastfeeding usage
8.3 Nursing Mothers Aripiprazole is present in human breast milk. Because of the potential for serious adverse reactions in nursing infants from aripiprazole, a decision should be made whether to discontinue nursing or to discontinue the drug, taking into account the importance of the drug to the mother.

Aripiprazole Solution Breastfeeding Analsys


Aripiprazole while Breastfeeding

Low Risk

CAS Number: 129722-12-9

ts pharmacokinetic data (low oral bioavailability, large volume of distribution, moderately elevated molecular weight and high plasma protein binding) explains the negligible or zero passage into milk observed (Grover 2015, Nordeng 2014, Watanabe 2011, Lutz 2010, Schlotterbeck 2007). No problems were observed in infants whose mothers were taking it (Nordeng 2014, Tarikh 2014, Lutz 2010). The plasma levels of these infants were undetectable or very low (Watanabe 2011). Its relationship with prolactin is controversial because it lowers prolactin levels and has been used to treat prolactinomas and hyperprolactinemia induced by the use of other antipsychotics (Bakker 2016, Ranjbar 2015, Raghuthaman 2015, Safer 2013, Byerly 2009, Lorenz 2007, Goodnick 2002), but cases of decreased milk production have been reported (Frew 2015, Mendhekar 2006) and hyperprolactinemia triggered by aripiprazole has been reported (Sogawa 2016, Prost 2016, Saraf 2014, Mendhekar 2005, Ruffatti 2005). Due to its slow elimination, it may be worthwhile using other compatible antipsychotics with a shorter half-life, especially during the neonatal period and in case of prematurity (Uguz 2016). Monitor for possible drowsiness in the infant (Hale 2017 p.74).

Aripiprazole Solution Breastfeeding Analsys - 2


Aripiprazole while Breastfeeding

CAS Number: 129722-12-9

Limited information indicates that maternal doses of aripiprazole up to 15 mg daily produce low levels in milk, but until more data become available, an alternate drug may be preferred, especially while nursing a newborn or preterm infant.[1] Aripiprazole can lower serum prolactin in a dose-related manner, but cases of gynecomastia and galactorrhea have also been reported.


What if I already have used Aripiprazole Solution?

Aripiprazole Solution is in the category of low risk, if you have already used it then its not a big deal if health and behavior of baby is good. However your health care provider shall be aware of the fact that you have used Aripiprazole Solution so you should inform him based on your convenience.


I am nursing mother and my doctor has suggested me to use Aripiprazole Solution, is it safe?

Aripiprazole Solution comes in category of low risk and if your doctor is aware that you are breastfeeding it should be ok to use without much concerns.


If I am using Aripiprazole Solution, will my baby need extra monitoring?

Not much monitoring required while using Aripiprazole Solution


Who can I talk to if I have questions about usage of Aripiprazole Solution in breastfeeding?

US
National Womens Health and Breastfeeding Helpline: 800-994-9662 (TDD 888-220-5446) 9 a.m. and 6 p.m. ET, Monday through Friday

UK
National Breastfeeding Helpline: 0300-100-0212 9.30am to 9.30pm, daily
Association of Breastfeeding Mothers: 0300-330-5453
La Leche League: 0345-120-2918
The Breastfeeding Network supporter line in Bengali and Sylheti: 0300-456-2421
National Childbirth Trust (NCT): 0300-330-0700

Australia
National Breastfeeding Helpline: 1800-686-268 24 hours a day, 7 days a week

Canada
Telehealth Ontario for breastfeeding: 1-866-797-0000 24 hours a day, 7 days a week

Drug Brands with same Active ingredients

Abilify Maintena | Aripiprazole Kit
Abilify Mycite | Aripiprazole Tablet