Wellbutrin Sr | Bupropion Hcl Er (sr) Tablet Breastfeeding

Do you know that important immune protective proteins are present in breast milk? Breast milk also contains required vitamins, minerals, saturated and un saturated fats. These things are extremely important for development of healthy brain. If you are taking any medicine for short term or for the chronic reason then that passes in breast milk as well, that is why you should always check the drug with your health care provider. Here at DrLact we try to analyze drugs based on available researches and in this sheet we will present our analysis for Wellbutrin Sr | Bupropion Hcl Er (sr) Tablet.

What is Wellbutrin Sr | Bupropion Hcl Er (sr) Tablet used for?


Bupropion hydrochloride extended-release tablets, USP (SR)are indicated for the treatment of major depressive disorder (MDD), as defined by the Diagnostic and Statistical Manual (DSM). The efficacy of bupropion in the treatment of a major depressive episode was established in two 4-week controlled inpatient trials and one 6-week controlled outpatient trial of adult subjects with MDD [see Clinical Studies (14)]. The efficacy of bupropion hydrochloride extended-release tablets, USP (SR) in maintaining an antidepressant response for up to 44 weeks following 8 weeks of acute treatment was demonstrated in a placebo-controlled trial [see Clinical Studies (14)].

I am currently breastfeeding and I want to know if using Wellbutrin Sr | Bupropion Hcl Er (sr) Tablet is safe for my kid? Does it have any effect on milk production?

Wellbutrin Sr | Bupropion Hcl Er (sr) Tablet low risk for breastfeeding
Wellbutrin Sr | Bupropion Hcl Er (sr) Tablet contains only one active ingredient that is Bupropion hydrochloride. We have analyzed the usage of Bupropion hydrochloride in breastfeeding and our analysis suggest that Bupropion hydrochloride poses Low risk for infant while breastfeeding and hence Wellbutrin Sr | Bupropion Hcl Er (sr) Tablet itself shall be considered Low risk item for breastfeeding.

Wellbutrin Sr | Bupropion Hcl Er (sr) Tablet Breastfeeding Analsys


Bupropion hydrochloride while Breastfeeding

Low Risk

CAS Number: 34911-55-2

Selective inhibitor of the neuronal reuptake of catecholamines (noradrenaline and dopamine). It is used as an antidepressant and to help stop smoking (Baraona 2017). Administered orally, one daily dose. Although the concentration in milk is much higher than the plasma concentration, it is excreted in breast milk in very small amounts (Neuman 2014, Davis 2009, Haas 2004, Briggs 1993). The plasma levels of infants whose mothers were taking it were undetectable or very low (Neuman 2014, Davis 2009, Baab 2002, Briggs 1993). Given the negligible excretion in milk, the absence of plasma levels in infants and the fact that no problems were observed in infants in several publications (Nonacs 2005, Baab 2002, Briggs 1993), two cases of seizures in infants whose mothers were taking bupropion are difficult to explain, whether in monotherapy (Chaudron 2004) or associated with other antidepressants (Neuman 2014). Progress was satisfactory. Bupropion does not alter prolactin levels (Whiteman 1982). Avoid in mothers with a history of epilepsy since it decreases the seizure threshold. Until there is more published data on this drug in relation to breastfeeding, safer alternatives known may be preferable (Sriraman 2015, Carson 2013, Berle 2011, Davanzo 2011), especially during the neonatal period and in case of prematurity. See below the information of these related products:


Wellbutrin Sr | Bupropion Hcl Er (sr) Tablet Breastfeeding Analsys - 2


Bupropion hydrochloride while Breastfeeding

CAS Number: 34911-55-2

Limited information indicates that maternal bupropion doses of up to 300 mg daily produce low levels in breastmilk and would not be expected to cause any adverse effects in breastfed infants. However, there is little reported use in breastfed newborn infants and case reports of a possible seizure in partially breastfed 6-month-olds. If bupropion is required by a nursing mother, it is not a reason to discontinue breastfeeding. However, another drug may be preferred, especially while nursing a newborn or preterm infant. Infants exposed to bupropion and an SSRI through breastfeeding should be closely monitored for vomiting, diarrhea, jitteriness, or sedation and possibly measurement of serum levels to rule out toxicity if there is a concern.



I already used Wellbutrin Sr | Bupropion Hcl Er (sr) Tablet and meanwhile I breastfed my baby should I be concerned?

During whole lactation period you shall first discuss with your doctor and then together you shall decide whether you shall take that drug or not however if you have already taken Wellbutrin Sr | Bupropion Hcl Er (sr) Tablet then you shall inform your doctor, But you should not be worried too much as Wellbutrin Sr | Bupropion Hcl Er (sr) Tablet comes in category of low risk drug.


My health care provider has asked me to use Wellbutrin Sr | Bupropion Hcl Er (sr) Tablet, what to do?

Wellbutrin Sr | Bupropion Hcl Er (sr) Tablet comes in category of low risk and if your doctor is aware that you are breastfeeding it should be ok to use without much concerns.


If I am using Wellbutrin Sr | Bupropion Hcl Er (sr) Tablet, will my baby need extra monitoring?

Not much


Who can I talk to if I have questions about usage of Wellbutrin Sr | Bupropion Hcl Er (sr) Tablet in breastfeeding?

US
National Womens Health and Breastfeeding Helpline: 800-994-9662 (TDD 888-220-5446) 9 a.m. and 6 p.m. ET, Monday through Friday

UK
National Breastfeeding Helpline: 0300-100-0212 9.30am to 9.30pm, daily
Association of Breastfeeding Mothers: 0300-330-5453
La Leche League: 0345-120-2918
The Breastfeeding Network supporter line in Bengali and Sylheti: 0300-456-2421
National Childbirth Trust (NCT): 0300-330-0700

Australia
National Breastfeeding Helpline: 1800-686-268 24 hours a day, 7 days a week

Canada
Telehealth Ontario for breastfeeding: 1-866-797-0000 24 hours a day, 7 days a week