Gentamicin Sulfate Solution while Breastfeeding

What is Gentamicin Sulfate Solution used for?

I am breastfeeding mother and I am using Gentamicin Sulfate Solution. Can it have any bad effect on my kid? Shall I search for better alternative?

Gentamicin while Breastfeeding

CAS Number: 1403-66-3

Excreted into breast milk in non-significant amount. Harmful effect has not been shown in breastfed infants whose mothers were treated with Gentamicin, except on case of a child who presented with bloody stools while the mother was receiving Gentamicin and Clindamycin. Low intestinal absorption leads to low or nil concentration in blood serum, with exception of premature infants or early neonatal period in which higher absorption may occur. Consider the possibility of false negative results of bacterial cultures among febrile breastfed infants whose mothers are treated with Gentamicin. Gastroenteritis due to intestinal flora imbalance is also likely. When eye drops are used like many other topical ophtalmologic preparations that use low doses with scanty excretion into serum are considered to be compatible with breastfeeding. The American Academy of Pediatrics rates it compatible with breastfeeding. The WHO Model List of Essential Medicines 2002 rates it as compatible with breastfeeding.

Gentamicin while Breastfeeding

CAS Number: 1403-66-3

Gentamicin is poorly excreted into breastmilk. Newborn infants apparently absorb small amounts of gentamicin, but serum levels with typical three times/day dosages are far below those attained when treating newborn infections and systemic effects of gentamicin are unlikely. Older infants would be expected to absorb even less gentamicin. Because there is little variability in the milk gentamicin levels during multiple daily dose regimens, timing breastfeeding with respect to the dose is of little or no benefit in reducing infant exposure. Data are not available with single daily dose regimens. Monitor the infant for possible effects on the gastrointestinal flora, such as diarrhea, candidiasis (e.g., thrush, diaper rash) or rarely, blood in the stool indicating possible antibiotic-associated colitis.Maternal use of an ear drop or eye drop that contains gentamicin presents little or no risk for the nursing infant.[1]

What should I do if I am breastfeeding mother and I am already exposed to Gentamicin Sulfate Solution?

I am nursing mother and my doctor has suggested me to use Gentamicin Sulfate Solution, is it safe?

If I am using Gentamicin Sulfate Solution, will my baby need extra monitoring?

Who can I talk to if I have questions about usage of Gentamicin Sulfate Solution in breastfeeding?