Solifenacine Succinate Tablet Breastfeeding

Do you know that important immune protective proteins are present in breast milk? Breast milk also contains required vitamins, minerals, saturated and un saturated fats. These things are extremely important for development of healthy brain. If you are taking any medicine for short term or for the chronic reason then that passes in breast milk as well, that is why you should always check the drug with your health care provider. Here at DrLact we try to analyze drugs based on available researches and in this sheet we will present our analysis for Solifenacine Succinate Tablet.

What is Solifenacine Succinate Tablet used for?


Solifenacin succinate is a muscarinic antagonist indicated for the treatment of overactive bladder with symptoms of urge urinary incontinence, urgency, and urinary frequency. Solifenacin succinate is a muscarinic antagonist indicated for the treatment of overactive bladder with symptoms of urge urinary incontinence, urgency, and urinary frequency (1).

I am breastfeeding mother and I am using Solifenacine Succinate Tablet. Can it have any bad effect on my kid? Shall I search for better alternative?

Solifenacine Succinate Tablet high risk while breastfeeding
As Solifenacine Succinate Tablet is made of only Solifenacin succinate, and Solifenacin succinate is unsafe to use in breastfeeding we can safely reach on conclusion that Solifenacine Succinate Tablet is also unsafe to use while breastfeeding. Below is detailed analysis of Solifenacin succinate and Solifenacine Succinate Tablet during location. We recommend you to go through provided detailed analysis as below take decision accordingly. We also recommend you talk to your health care provider before making final decision.

Statement of Manufacturer/Labeler about breastfeeding usage
8.3 Nursing Mothers After oral administration of 14C-solifenacin succinate to lactating mice, radioactivity was detected in maternal milk. There were no adverse observations in mice treated with 1.2 times (30 mg/kg/day) the expected exposure at the maximum recommended human dose [MRHD]. Pups of female mice treated with 3.6 times (100 mg/kg/day) the exposure at the MRHD or greater revealed reduced body weights, postpartum pup mortality or delays in the onset of reflex and physical development during the lactation period. It is not known whether solifenacin is excreted in human milk. Because many drugs are excreted in human milk, solifenacin succinate tablets should not be administered during nursing. A decision should be made whether to discontinue nursing or to discontinue solifenacin succinate tablets in nursing mothers.

Solifenacine Succinate Tablet Breastfeeding Analsys


Solifenacin succinate while Breastfeeding

Unsafe

Advice to take a minimal dose for a short time since anti-cholinergic drugs may decrease breast milk production. Check-up for anti-cholinergic symptoms (mouth dryness, constipation...)

Solifenacine Succinate Tablet Breastfeeding Analsys - 2


Solifenacin succinate while Breastfeeding

CAS Number: 242478-37-1

Because there is no published experience with solifenacin during breastfeeding and it has a long half-life averaging 55 hours, an alternate drug may be preferred, especially while nursing a newborn or preterm infant. Long-term use of solifenacin might reduce milk production or milk letdown. During long-term use, observe the infant for signs of decreased milk production (e.g., insatiety, poor weight gain) and for anticholinergic symptoms (e.g., constipation, urinary retention, UTI, dry mouth).

Solifenacine Succinate Tablet and breastfeeding

I already used Solifenacine Succinate Tablet and meanwhile I breastfed my baby should I be concerned?

We have already established that Solifenacine Succinate Tablet is unsafe in breastfeeding and breastfeeding while using Solifenacine Succinate Tablet is not a good idea however if have already used and then breastfed the baby then you shall monitor the behavior and health of baby closely and inform your doctor as soon as possible. In case of emergency please call 911.


I am nursing mother and my doctor has suggested me to use Solifenacine Succinate Tablet, is it safe?

If your doctor knows that you are breastfeeding mother and still prescribes Solifenacine Succinate Tablet then there must be good reason for that as Solifenacine Succinate Tablet is considered unsafe, It usually happens when doctor finds that overall advantage of taking outweighs the overall risk.


If I am using Solifenacine Succinate Tablet, will my baby need extra monitoring?

Yes, Extra monitoring is required if mother is using Solifenacine Succinate Tablet and breastfeeding as it is considered unsafe for baby.


Who can I talk to if I have questions about usage of Solifenacine Succinate Tablet in breastfeeding?

US
National Womens Health and Breastfeeding Helpline: 800-994-9662 (TDD 888-220-5446) 9 a.m. and 6 p.m. ET, Monday through Friday

UK
National Breastfeeding Helpline: 0300-100-0212 9.30am to 9.30pm, daily
Association of Breastfeeding Mothers: 0300-330-5453
La Leche League: 0345-120-2918
The Breastfeeding Network supporter line in Bengali and Sylheti: 0300-456-2421
National Childbirth Trust (NCT): 0300-330-0700

Australia
National Breastfeeding Helpline: 1800-686-268 24 hours a day, 7 days a week

Canada
Telehealth Ontario for breastfeeding: 1-866-797-0000 24 hours a day, 7 days a week