Minoxidil 7% / Progesterone 0.1% / Tretinoin 0.025% Solution while Breastfeeding

Can I continue breastfeeding if I am using Minoxidil 7% / Progesterone 0.1% / Tretinoin 0.025% Solution? How long does it stays in breast milk?

Progesterone while Breastfeeding

CAS Number: 57-83-0

Excreted into breast milk in a non-significant amount with no side-effects observed in breastfed infants of treated mothers. The plasma levels in those infants have been undetectable or very low. During the first 6 weeks after birth, non-hormonal methods are of choice as contraceptives. If associated to estrogens may inhibit lactation. It is recommended the use of contraceptive medication that does not contain estrogens, or, better if it contains progestogen alone.

Minoxidil while Breastfeeding

CAS Number: 38304-91-5

It is excreted into breast milk in non-significant amount without side-effects observed among infants whose mothers were taking this medication. This small risk can further be minimized by avoiding to nurse one hour after taking the medication, a time at which milk level is higher (4, 10, 20 and 40 times higher than if occurs within 3, 6, 9 and 12 hours respectively) The American Academy of Pediatrics states that it is usually compatible with breastfeeding. Because, few published experience is available, it would be preferred better known options, especially within the neonatal period or in case of prematurity.

Tretinoin while Breastfeeding

Retinoid, an acid form of vitamin A. At latest update no published data on excretion into breast milk were found.It is a normal component of breastmilk. Because of the small dose used and poor absorption into plasma of most topical dermatological preparations, excretion into breastmilk in significant amount appears to be unlikely. Do not apply on the breast, otherwise, wash it off thoroughly before next feed. Systemic use (overall as an antineoplastic drug) while breastfeeding is absolutely contraindicated.

Progesterone while Breastfeeding

CAS Number: 57-83-0

Release from the progesterone-releasing intrauterine device available in the United States is 65 mcg/day or only 0.65% of the dose released from most of the devices reported in the literature. Because of the low levels of progesterone in breastmilk, even with the high-dose products, amounts ingested by the infant are small and would not be expected to cause any adverse effects in breastfed infants. The progesterone vaginal ring available in some countries produces maternal blood levels that are lower than those of ovulating women.[1] Most studies indicate that progesterone is not detrimental to milk production or duration of nursing.[2][3] No special precautions appear to be required. In Russia, a progesterone gel (Progestogel - Besins Healthcare; not available in the US) has been used topically as a one-time application to the breasts to treat postpartum breast engorgement when more conservative measures have failed.[4] A subsequent study failed to detect any decrease in breast hardness 20 minutes after application of progesterone gel in mothers with engorgement.[5] The safety and efficacy of this use have not been well studied and the manufacturer of Progestogel recommends avoiding its use during lactation.

Minoxidil while Breastfeeding

CAS Number: 38304-91-5

Because of the minimal amount of information on this potent agent, use minoxidil with caution, particularly when therapy involves a large maternal dosage or breastfeeding a newborn. Topical minoxidil should pose low risk to the breastfed infant.

Tretinoin while Breastfeeding

CAS Number: 302-79-4

Tretinoin has not been studied during breastfeeding. Breastfeeding should probably be avoided after oral use. Because it is poorly absorbed after topical application, it is considered a low risk to the nursing infant.[1][2][3] Ensure that the infant's skin does not come into direct contact with the areas of skin that have been treated. Only water-miscible cream or gel products should be applied to the breast because ointments may expose the infant to high levels of mineral paraffins via licking.[4]

I am nursing mother and I have already used Minoxidil 7% / Progesterone 0.1% / Tretinoin 0.025% Solution, what should I do?

My health care provider has asked me to use Minoxidil 7% / Progesterone 0.1% / Tretinoin 0.025% Solution, what to do?

If I am using Minoxidil 7% / Progesterone 0.1% / Tretinoin 0.025% Solution, will my baby need extra monitoring?

Who can I talk to if I have questions about usage of Minoxidil 7% / Progesterone 0.1% / Tretinoin 0.025% Solution in breastfeeding?