Clindamycin 1% / Niacinamide 4% / Tretinoin 0.05% Cream while Breastfeeding
Modern medicine has evolved so much so that sooner or later every breastfeeding mother needs to take it in one form or other. Medication that is present in mothers blood will transfer into her breast milk to some extent. Most drugs do so at low levels and pose no real risk to infants but then there are some exceptions. In This post will discuss whether Clindamycin 1% / Niacinamide 4% / Tretinoin 0.05% Cream is safe in breast-feeding or not.

Is Clindamycin 1% / Niacinamide 4% / Tretinoin 0.05% Cream safe to use while breastfeeding? Can it interfere with growth and development of my kid?

Clindamycin 1% / Niacinamide 4% / Tretinoin 0.05% Cream low risk for breastfeeding
Task to evaluate the effect of Clindamycin 1% / Niacinamide 4% / Tretinoin 0.05% Cream is quite difficult as it consist mainly 3 ingredients. However we have analyzed all 3 active ingredients and have reached a conclusion that Clindamycin 1% / Niacinamide 4% / Tretinoin 0.05% Cream poses low risk while breastfeeding. Below we have summarized our analysis of each 3 ingredients.

Clindamycin 1% / Niacinamide 4% / Tretinoin 0.05% Cream Breastfeeding Analsys


Niacinamide while Breastfeeding

Safe

CAS Number: 98-92-0

A balanced and comprehensive diet make it vitamin supplementation useless.

Clindamycin phosphate while Breastfeeding

Low Risk

CAS Number: 18323-44-9

Lincosamide antibacterial. Excreted in non-significant level into breast milk. Except for few cases of enterocolitis due to disturbance of intestinal flora no other harm effects have been shown in breastfed infants. All cases spontaneously cured after discontinuation of medication. One reported case (1980) of pseudomembrane colitis in an infant whose mother was on clindamicin and gentamicin. Be aware of the possibility of false negative results of febrile infant bacterial cultures when the mother is on antibiotics and diarrheal disease due to intestinal flora imbalance. The American Academy of Pediatrics rates it as compatible with breastfeeding.

Alitretinoin while Breastfeeding

Safe

Retinoid, an acid form of vitamin A. At latest update no published data on excretion into breast milk were found.It is a normal component of breastmilk. Because of the small dose used and poor absorption into plasma of most topical dermatological preparations, excretion into breastmilk in significant amount appears to be unlikely. Do not apply on the breast, otherwise, wash it off thoroughly before next feed. Systemic use (overall as an antineoplastic drug) while breastfeeding is absolutely contraindicated.


Clindamycin 1% / Niacinamide 4% / Tretinoin 0.05% Cream Breastfeeding Analsys - 2


Clindamycin phosphate while Breastfeeding

CAS Number: 18323-44-9

Clindamycin has the potential to cause adverse effects on the breastfed infant's gastrointestinal flora. If oral or intravenous clindamycin is required by a nursing mother, it is not a reason to discontinue breastfeeding, but an alternate drug may be preferred. Monitor the infant for possible effects on the gastrointestinal flora, such as diarrhea, candidiasis (thrush, diaper rash) or rarely, blood in the stool indicating possible antibiotic-associated colitis. Vaginal application is unlikely to cause infant side effects, although about 30% of a vaginal dose is absorbed. Infant side effects are unlikely with topical administration for acne; however, topical application to the breast may increase the risk of diarrhea if it is ingested by the infant. Only water-miscible cream, foam, gel or liquid products should be applied to the breast because ointments may expose the infant to high levels of mineral paraffins via licking.[1]



I am nursing mother and I have already used Clindamycin 1% / Niacinamide 4% / Tretinoin 0.05% Cream, what should I do?

Clindamycin 1% / Niacinamide 4% / Tretinoin 0.05% Cream is in the category of low risk, if you have already used it then its not a big deal if health and behavior of baby is good. However your health care provider shall be aware of the fact that you have used Clindamycin 1% / Niacinamide 4% / Tretinoin 0.05% Cream so you should inform him based on your convenience.


My health care provider has asked me to use Clindamycin 1% / Niacinamide 4% / Tretinoin 0.05% Cream, what to do?

Though Clindamycin 1% / Niacinamide 4% / Tretinoin 0.05% Cream dose not comes in category of safe drugs rather it comes in category of low risk but if your doctor is aware that you are breastfeeding your baby and has still recommended it then its advantages must be outweighing the risks.


If I am using Clindamycin 1% / Niacinamide 4% / Tretinoin 0.05% Cream, will my baby need extra monitoring?

Not much monitoring required while using Clindamycin 1% / Niacinamide 4% / Tretinoin 0.05% Cream


Who can I talk to if I have questions about usage of Clindamycin 1% / Niacinamide 4% / Tretinoin 0.05% Cream in breastfeeding?

US
National Womens Health and Breastfeeding Helpline: 800-994-9662 (TDD 888-220-5446) 9 a.m. and 6 p.m. ET, Monday through Friday

UK
National Breastfeeding Helpline: 0300-100-0212 9.30am to 9.30pm, daily
Association of Breastfeeding Mothers: 0300-330-5453
La Leche League: 0345-120-2918
The Breastfeeding Network supporter line in Bengali and Sylheti: 0300-456-2421
National Childbirth Trust (NCT): 0300-330-0700

Australia
National Breastfeeding Helpline: 1800-686-268 24 hours a day, 7 days a week

Canada
Telehealth Ontario for breastfeeding: 1-866-797-0000 24 hours a day, 7 days a week