Antibiotic Plus Pain Relief | Neomycin, Polymyxin B, Pramoxine Hydrochloride Cream while Breastfeeding

What is Antibiotic Plus Pain Relief | Neomycin, Polymyxin B, Pramoxine Hydrochloride Cream ?

Can I use Antibiotic Plus Pain Relief | Neomycin, Polymyxin B, Pramoxine Hydrochloride Cream while breastfeeding?

Neomycin while Breastfeeding

CAS Number: 1404-04-2

Aminoglycoside antibiotic which is used in creams, eye drops, and otologic preparations for topical use, and, also orally used for intestinal disinfection. At latest update, relevant published data on excretion in the breast milk were not found. Like other aminoglycoside antibiotics, Neomycin is not absorbed by the gut. Absorption from other sources like skin, nose, ear and eye mucosa by means of topically used preparations (creams, drops, etc.) is very poor which causes excretion into breast milk in significant amount, unlikely. Do not apply creams, gels and other products that would contain paraffin (mineral oil) to avoid absorption by the infant since it is a hydrocarbon-derived substance. In case of use of Neomycin on the nipple, let it be done after the feed and wipe it out any excess of cream before the next feed. Be aware of false negative results of microbial cultures done from samples of febrile infants whose mothers are treated with antibiotics. Also, due to imbalance of intestinal flora a diarrheal disease can occur in the breastfed infant. List of Essential Medicines by WHO 2002: compatible with breastfeeding.

Pramoxine hydrochloride while Breastfeeding

CAS Number: 140-65-8

Anesthetic drugs for topical use, both dermatological and odontological, have almost nil absorption when properly used. Do not apply on the breast. Otherwise, do it after having nursed, and cleanse it thoroughly with water before next feeding.

Polymyxin b while Breastfeeding

CAS Number: 1405-20-5

Antibiotic drug that is usual topically used (Dermatology, ENT and Ophthalmology) At latest update no published data on excretion into breast milk were found. The small dose and low absorption to the plasma in a majority of preparations that are topically used on the eye, ear or skin make a significant excretion into the milk unlikely. Its high molecular weight makes less probable an excretion into breast milk in significant amount. Due to a poor oral bioavailability, appearance in the infant's plasma from ingested milk is regarded as nil or scanty, except in premature infants or during the immediate neonatal period who may show an increased intestinal absorption. Polymyxin E or Colistin with a very similar molecular structure is excreted into breast milk in non-significant amount. It is advisable to avoid the application of creams, gels and other products for local use that would contain paraffin (mineral oil) to prevent absorption by the infant.

Neomycin while Breastfeeding

CAS Number: 1404-04-2

Although no information exists on the excretion of neomycin into milk, other aminoglycoside antibiotics are poorly excreted into breastmilk. Newborn infants apparently absorb small amounts of aminoglycosides, but serum levels are far below those attained when treating newborn infections and systemic effects of neomycin are unlikely. Older infants would be expected to absorb even less neomycin. Monitor the infant for possible effects on the gastrointestinal flora, such as diarrhea, candidiasis (e.g., thrush, diaper rash) or rarely, blood in the stool indicating possible antibiotic-associated colitis. Oral, topical, ophthalmic or otic neomycin should result in very low levels in breastmilk and present negligible risk to the infant,[1][2] although topical application to the nipple may increase the risk of diarrhea in the infant. Only water-miscible cream or gel products should be applied to the breast because ointments may expose the infant to high levels of mineral paraffins via licking.[3]

Polymyxin b while Breastfeeding

CAS Number: 1404-26-8

Because it is poorly absorbed after topical application, polymyxin B is considered a low risk to the nursing infant.[1] Only water-miscible cream or gel products should be applied to the breast because ointments may expose the infant to high levels of mineral paraffins via licking.[2]

What should I do if I am breastfeeding mother and I am already exposed to Antibiotic Plus Pain Relief | Neomycin, Polymyxin B, Pramoxine Hydrochloride Cream?

My doctor has prescribed me Antibiotic Plus Pain Relief | Neomycin, Polymyxin B, Pramoxine Hydrochloride Cream, what should I do?

If I am using Antibiotic Plus Pain Relief | Neomycin, Polymyxin B, Pramoxine Hydrochloride Cream, will my baby need extra monitoring?

Who can I talk to if I have questions about usage of Antibiotic Plus Pain Relief | Neomycin, Polymyxin B, Pramoxine Hydrochloride Cream in breastfeeding?