Nitroglycerin Ointment while Breastfeeding

What is Nitroglycerin Ointment used for?

Is Nitroglycerin Ointment usage safe while breastfeeding? If a lactating mother is using it can there be any effect on growth or development of infant?

Nitroglycerin while Breastfeeding

CAS Number: 55-63-0

Vasodilator used to treat cardiac disorders like ischemia and mainly anal fissures.It is also used during pregnancy as a tocolytic drug in cases of threatened preterm labor and eclampsia.It has been used to treat heart disorders in babies and children. Even to treat anal fissures in children under 1 year, and noteworthy, in ischemic issues on premature infants without side effects.It is administered intravenously, orally, sublingually, on skin patches, ointment ... Because of a moderately-high volume of distribution and very fast metabolism (Tmax and t1 / 2 minutes) it is highly unlikely the passage of significant amounts to the breast milk, especially when applied topically. This explains why it has not been observed any troubles in 40 infants whose mothers with anal fissures were treated with nitroglycerin ointment application even for periods of 12 months. Mothers have complained of headaches that commonly occur with the use of various vasodilators drugs. The amount of nitrate / nitrite in this type of vasodilator drugs is of few milligrams, therefore, toxicity associated to nitrates such as methemoglobinemia in breastfed infants from treated mothers has not been reported (The dose of nitrite is Rectogesic 1.5 mg / 12 hours).

Nitroglycerin while Breastfeeding

CAS Number: 55-63-0

Topical use of nitroglycerin for anal fissures by nursing mothers appears to have no adverse effects on their breastfed infants. Topical use on the nipples has been used for alleviation of Raynaud phenomenon of the nipples, but only after cessation of breastfeeding.[1] Nitroglycerin should not be used topically on the nipples during breastfeeding. Sublingual and intravenous nitroglycerin have not been studied during breastfeeding. Observe infants for flushing and discomfort after breastfeeding.

What should I do if I am breastfeeding mother and I am already exposed to Nitroglycerin Ointment?

I am nursing mother and my doctor has suggested me to use Nitroglycerin Ointment, is it safe?

If I am using Nitroglycerin Ointment, will my baby need extra monitoring?

Who can I talk to if I have questions about usage of Nitroglycerin Ointment in breastfeeding?