Modern medicine has evolved so much so that sooner or later every breastfeeding mother needs to take it in one form or other. Medication that is present in mothers blood will transfer into her breast milk to some extent. Most drugs do so at low levels and pose no real risk to infants but then there are some exceptions. In This post will discuss whether Sulfamethoxazole And Trimethoprim Injection is safe in breast-feeding or not.
What is Sulfamethoxazole And Trimethoprim Injection used for?
Sulfamethoxazole and trimethoprim injection is a combination of sulfamethoxazole, a sulfonamide antimicrobial, and trimethoprim, a dihydrofolate reductase inhibitor antibacterial, indicated in adults and pediatric patients two months of age and older for treatment of infections caused by designated, susceptible bacteria. • Pneumocystis jirovecii Pneumonia (1.1) •Shigellosis (1.2) •Urinary Tract Infections (1.3) To reduce the development of drug-resistant bacteria and maintain the effectiveness of sulfamethoxazole and trimethoprim injection and other antibacterial drugs, sulfamethoxazole and trimethoprim injection should be used only to treat or prevent infections that are proven or strongly suspected to be caused by susceptible bacteria. (1.4) 1.1 Pneumocystis jirovecii Pneumonia Sulfamethoxazole and trimethoprim injection is indicated in the treatment of Pneumocystis jirovecii pneumonia in adults and pediatric patients two months of age and older. 1.2 Shigellosis Sulfamethoxazole and trimethoprim injection is indicated in the treatment of enteritis caused by susceptible strains of Shigella flexneri and Shigella sonnei in adults and pediatric patients two months of age and older. 1.3 Urinary Tract Infections Sulfamethoxazole and trimethoprim injection is indicated in the treatment of severe or complicated urinary tract infections in adults and pediatric patients two months of age and older due to susceptible strains of Escherichia coli, Klebsiella species, Enterobacter species, Morganella morganii and Proteus species when oral administration of sulfamethoxazole and trimethoprim injection is not feasible and when the organism is not susceptible to single-agent antibacterials effective in the urinary tract. 1.4 Usage To reduce the development of drug-resistant bacteria and maintain the effectiveness of sulfamethoxazole and trimethoprim injection and other antibacterial drugs, sulfamethoxazole and trimethoprim injection should be used only to treat or prevent infections that are proven or strongly suspected to be caused by susceptible bacteria. When culture and susceptibility information are available, they should be considered in selecting or modifying antibacterial therapy. In the absence of such data, local epidemiology and susceptibility patterns may contribute to empiric selection of therapy. Although appropriate culture and susceptibility studies should be performed, therapy may be started while awaiting the results of these studies.
I am currently breastfeeding and I want to know if using Sulfamethoxazole And Trimethoprim Injection is safe for my kid? Does it have any effect on milk production?
Sulfamethoxazole And Trimethoprim Injection is primarily made of two things Sulfamethoxazole, Trimethoprim. What we have done here is we have analyzed Sulfamethoxazole for its impact on breastfeeding and analyzed Trimethoprim for its impact on breastfeeding. Our analysis of Sulfamethoxazole and Trimethoprim suggests that Sulfamethoxazole And Trimethoprim Injection is probably safe in breastfeeding however we suggest you to check detail about both below.
Sulfamethoxazole And Trimethoprim Injection Breastfeeding Analsys
SafeCAS Number: 723-46-6
Excreted in non-significant levels into breast milk. No adverse effects have been shown in breastfed infants. Caution with those neonates suffering of hyperbilirrubinemia or G-6-P-D deficiency is required. Avoid use in affected patients Check-up for infant jaundice. Be aware of false negative results of bacterial cultures when the mother is on antibiotics. American Academy of Pediatrics: Maternal Medication Usually Compatible With Breastfeeding.Eleventh WHO Model List of Essential Drugs 2002: Compatible with breastfeeding.
SafeCAS Number: 738-70-5
It is excreted in breast milk in clinically non-significant amount. No problems have been observed in infants whose mothers were treated. Medication which is used in infants from the second month of age. Take into account the possibility of negative false results of cultures from febrile infants whose mothers are taking antibiotics as well as the possibility of acute diarrhea due to imbalance of the intestinal flora. The American Academy of Pediatric states that it is usually compatible with breastfeeding medication.WHO List of Essential Medicines from 2002 has classified it as compatible with breastfeeding.
Sulfamethoxazole And Trimethoprim Injection Breastfeeding Analsys - 2
CAS Number: 723-46-6
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With healthy, fullterm infants it appears acceptable to use sulfamethoxazole during breastfeeding after the newborn period. The time of greatest risk for hemolysis in fullterm newborns without glucose-6-phosphate dehydrogenase (G6PD) deficiency might be as short as 8 days after birth.[1] Until further data are accumulated, alternate agents should probably be used in jaundiced, ill, stressed or premature infants, because of the risk of bilirubin displacement and kernicterus. Sulfamethoxazole should be avoided while breastfeeding a G6PD deficient infant.[2]
CAS Number: 738-70-5
Because of the low levels of trimethoprim in breastmilk, amounts ingested by the infant are small and would not be expected to cause any adverse effects in breastfed infants.
I am nursing mother and I have already used Sulfamethoxazole And Trimethoprim Injection, what should I do?
As usage of Sulfamethoxazole And Trimethoprim Injection is mostly safe while breastfeeding hence there should not be any concern. In case of any change in behavior or health of your baby you should inform your health care provider about usage of Sulfamethoxazole And Trimethoprim Injection else no further action is required.
My health care provider has asked me to use Sulfamethoxazole And Trimethoprim Injection, what to do?
Definitely, Sulfamethoxazole And Trimethoprim Injection is safe in lactation for baby. No wonder your doctor has recommended it.
If I am using Sulfamethoxazole And Trimethoprim Injection, will my baby need extra monitoring?
No extra baby monitoring required while mother is using Sulfamethoxazole And Trimethoprim Injection
Who can I talk to if I have questions about usage of Sulfamethoxazole And Trimethoprim Injection in breastfeeding?
US
National Womens Health and Breastfeeding Helpline: 800-994-9662 (TDD 888-220-5446) 9 a.m. and 6 p.m. ET, Monday through Friday
UK
National Breastfeeding Helpline: 0300-100-0212 9.30am to 9.30pm, daily
Association of Breastfeeding Mothers: 0300-330-5453
La Leche League: 0345-120-2918
The Breastfeeding Network supporter line in Bengali and Sylheti: 0300-456-2421
National Childbirth Trust (NCT): 0300-330-0700
Australia
National Breastfeeding Helpline: 1800-686-268 24 hours a day, 7 days a week
Canada
Telehealth Ontario for breastfeeding: 1-866-797-0000 24 hours a day, 7 days a week
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