Epinephrine Injection, Solution, Concentrate while Breastfeeding

What is Epinephrine Injection, Solution, Concentrate used for?

I am currently breastfeeding and I want to know if using Epinephrine Injection, Solution, Concentrate is safe for my kid? Does it have any effect on milk production?

Epinephrine while Breastfeeding

CAS Number: 51-43-4

Used as a systemic drug for cardiac resuscitation and locally in topical anesthetic preparations, epidural anesthesia, eye drops (mydriatic), and nasal drops (vasoconstrictor). At last update no published data on excretion in breast milk were found.Its rapid metabolism (short Tmax and T½) makes it unlikely an excretion into milk in significant amounts. It is destroyed in the gastrointestinal tract. The low oral-bioavailability makes its levels into infant's plasma, that would be absorbed from ingested breast milk, be nil or negligible. Maintained high intravenous doses decrease milk production by interfering with the secretion of prolactin especially the early postpartum-weeks, because when breastfeeding is well established, prolactin levels do not correlate with milk production any longer. No problems related to lactation have been observed due to epidural anesthesia in which adrenaline is used.

Epinephrine while Breastfeeding

CAS Number: 51-43-4

No information is available on the use of epinephrine during breastfeeding. Because of its poor oral bioavailability and short half-life, any epinephrine in milk is unlikely to affect the infant. High intravenous doses of epinephrine might reduce milk production or milk letdown. Low-dose intramuscular (such as Epi-Pen), epidural, topical, inhaled or ophthalmic epinephrine are unlikely to interfere with breastfeeding. To substantially diminish the effect of the drug after using eye drops, place pressure over the tear duct by the corner of the eye for 1 minute or more, then remove the excess solution with an absorbent tissue.

What if I already have used Epinephrine Injection, Solution, Concentrate?

My health care provider has asked me to use Epinephrine Injection, Solution, Concentrate, what to do?

If I am using Epinephrine Injection, Solution, Concentrate, will my baby need extra monitoring?

Who can I talk to if I have questions about usage of Epinephrine Injection, Solution, Concentrate in breastfeeding?