Argatroban Solution Breastfeeding

It is a well known fact that breastfeeding is best source of nutrition for infants. Breast milk provides minerals, vitamins and antibodies in most acceptable format when they need it. Nutrition taken by mother passes to breast-milk and same thing applies to medicines taken by mothers. Not all drugs cause problem for baby but some do. Lets analyze if Argatroban Solution is safe for baby while breastfed.

What is Argatroban Solution used for?


1 INDICATIONS & USAGE Argatroban is a direct thrombin inhibitor indicated: For prophylaxis or treatment of thrombosis in adult patients with heparin-induced thrombocytopenia (HIT) (1.1) As an anticoagulant in adults patients with or at risk for HIT undergoing percutaneous coronary intervention (PCI) (1.2) 1.1 Heparin-Induced Thrombocytopenia Argatroban Injection is indicated for prophylaxis or treatment of thrombosis in adult patients with heparin-induced thrombocytopenia (HIT). 1.2 Percutaneous Coronary Intervention Argatroban Injection is indicated as an anticoagulant in adult patients with or at risk for HIT undergoing percutaneous coronary intervention (PCI).

Is Argatroban Solution usage safe while breastfeeding? If a lactating mother is using it can there be any effect on growth or development of infant?

Argatroban Solution high risk while breastfeeding
As Argatroban Solution is made of only Argatroban anhydrous, and Argatroban anhydrous is unsafe to use in breastfeeding we can safely reach on conclusion that Argatroban Solution is also unsafe to use while breastfeeding. Below is detailed analysis of Argatroban anhydrous and Argatroban Solution during location. We recommend you to go through provided detailed analysis as below take decision accordingly. We also recommend you talk to your health care provider before making final decision.

Statement of Manufacturer/Labeler about breastfeeding usage
8.3 Nursing Mothers It is not known whether argatroban is excreted in human milk. Argatroban is detected in rat milk. Because many drugs are excreted in human milk and because of the potential for serious adverse reactions in nursing infants from argatroban, a decision should be made whether to discontinue nursing or to discontinue the drug, taking into account the importance of the drug to the mother.

Argatroban Solution Breastfeeding Analsys


Argatroban anhydrous while Breastfeeding

Unsafe

CAS Number: 74863-84-6

On latest update relevant data on breastfeeding was not found. Absorption by the intestine is unknown. Although a better known and safer alternative is preferred, because of short half-life a delay of 3-4 hours period after last dose would permit to minimize any risk.

Argatroban Solution Breastfeeding Analsys - 2


Argatroban anhydrous while Breastfeeding

CAS Number: 141396-28-3

If argatroban is required by the mother, it is not a reason to discontinue breastfeeding, but because no information is available on the use of argatroban during breastfeeding, an alternate drug is preferred.[1]


What should I do if already breastfed my kid after using Argatroban Solution?

If you observer abnormal behavior or any other health issue in infant then you should immediately call 911 or contact other contact other emergency service provider in your area otherwise closely monitor the baby and inform your doctor about your Argatroban Solution usage and time interval of breastfeeding.


I am nursing mother and my doctor has suggested me to use Argatroban Solution, is it safe?

If your doctor knows that you are breastfeeding mother and still prescribes Argatroban Solution then there must be good reason for that as Argatroban Solution is considered unsafe, It usually happens when doctor finds that overall advantage of taking outweighs the overall risk.


If I am using Argatroban Solution, will my baby need extra monitoring?

Yes, Extra monitoring is required if mother is using Argatroban Solution and breastfeeding as it is considered unsafe for baby.


Who can I talk to if I have questions about usage of Argatroban Solution in breastfeeding?

US
National Womens Health and Breastfeeding Helpline: 800-994-9662 (TDD 888-220-5446) 9 a.m. and 6 p.m. ET, Monday through Friday

UK
National Breastfeeding Helpline: 0300-100-0212 9.30am to 9.30pm, daily
Association of Breastfeeding Mothers: 0300-330-5453
La Leche League: 0345-120-2918
The Breastfeeding Network supporter line in Bengali and Sylheti: 0300-456-2421
National Childbirth Trust (NCT): 0300-330-0700

Australia
National Breastfeeding Helpline: 1800-686-268 24 hours a day, 7 days a week

Canada
Telehealth Ontario for breastfeeding: 1-866-797-0000 24 hours a day, 7 days a week