Ozurdex | Dexamethasone Implant while Breastfeeding

What is Ozurdex | Dexamethasone Implant used for?

Ozurdex | Dexamethasone Implant while breastfeeding safe or not? Can there be any side effects for infant while using it during breastfeeding?

Dexamethasone while Breastfeeding

CAS Number: 50-02-2

Pharmacokinetic data indicate that excretion into breast milk in significant levels is possible, hence for long term treatments other steroids with lower excretion would be advisable. Other steroids (Betamethasone) that are administered prior to delivery can produce a delay of Lactogenesis phase II (milk's coming in) and a decrease of milk production within the first post-partum week. Intra-articular injected large doses of other steroids (Triamcinolone, Methylprednisolone) may transiently affect milk production. A decrease of prolactin release after administration of dexamethasone has been observed that may decrease milk production mostly in the first post-partum weeks. Topical use: Because of a low absorption through skin significant excretion into breast milk is unlikely. Additionally, a high protein binding makes excretion even more unlikely. Whenever a treatment for nipple eczema or dermatitis is required the lowest potency steroid compound should be used. It should be applied right after the feed to make sure it has disappeared before the next nursing occurs. Otherwise, wipe cream out with a clean gauze. Do not continuously use for longer than a week. Reportedly, a case of mineral-steroid toxicity has occurred due to continuous use of cream on the nipple. Creams, gels or similar products that contain paraffin or mineral oil should not be used on the nipple to avoid absorption by the infant. Corticoids are frequently prescribed in Pediatrics with no side effects on the infant when indicated for short-term or sporadical use. On nursing mothers a timely use or not long-term treatment is compatible with breastfeeding along with the assessment of milk production. WHO Model List of Essential Drugs 2002: Compatible with breastfeeding in single dose. No data is available on long-term use.

Dexamethasone while Breastfeeding

CAS Number: 50-02-2

Because no information is available on the use of systemic dexamethasone during breastfeeding, an alternate corticosteroid may be preferred, especially while nursing a newborn or preterm infant. Local injections, such as for tendinitis, would not be expected to cause any adverse effects in breastfed infants, but might occasionally cause temporary loss of milk supply.

I am nursing mother and I have already used Ozurdex | Dexamethasone Implant, what should I do?

I am nursing mother and my doctor has suggested me to use Ozurdex | Dexamethasone Implant, is it safe?

If I am using Ozurdex | Dexamethasone Implant, will my baby need extra monitoring?

Who can I talk to if I have questions about usage of Ozurdex | Dexamethasone Implant in breastfeeding?