Zorcaine | Articaine Hydrochloride And Epinephrine Bitartrate Injection while Breastfeeding

What is Zorcaine | Articaine Hydrochloride And Epinephrine Bitartrate Injection ?

Is using Zorcaine | Articaine Hydrochloride And Epinephrine Bitartrate Injection safe or dangerous while breastfeeding?

Articaine hydrochloride while Breastfeeding

CAS Number: 23964-58-1

On latest update relevant data on breastfeeding was not found. Similar chemical structure to Lidocaine which is excreted into breast milk in minimal amount. Anesthetic drugs for topical use both dermatological and odontological have almost nil absorption when properly used.

Epinephrine while Breastfeeding

CAS Number: 51-43-4

Used as a systemic drug for cardiac resuscitation and locally in topical anesthetic preparations, epidural anesthesia, eye drops (mydriatic), and nasal drops (vasoconstrictor). At last update no published data on excretion in breast milk were found.Its rapid metabolism (short Tmax and T½) makes it unlikely an excretion into milk in significant amounts. It is destroyed in the gastrointestinal tract. The low oral-bioavailability makes its levels into infant's plasma, that would be absorbed from ingested breast milk, be nil or negligible. Maintained high intravenous doses decrease milk production by interfering with the secretion of prolactin especially the early postpartum-weeks, because when breastfeeding is well established, prolactin levels do not correlate with milk production any longer. No problems related to lactation have been observed due to epidural anesthesia in which adrenaline is used.

Articaine hydrochloride while Breastfeeding

CAS Number: 23964-58-1

No information is available on the use of articaine during breastfeeding. Based on the low excretion of other local anesthetics into breastmilk, a single dose of articaine injected during breastfeeding is unlikely to adversely affect the breastfed infant. However, an alternate drug may be preferred, especially while nursing a newborn or preterm infant.

Epinephrine while Breastfeeding

CAS Number: 51-43-4

No information is available on the use of epinephrine during breastfeeding. Because of its poor oral bioavailability and short half-life, any epinephrine in milk is unlikely to affect the infant. High intravenous doses of epinephrine might reduce milk production or milk letdown. Low-dose intramuscular (such as Epi-Pen), epidural, topical, inhaled or ophthalmic epinephrine are unlikely to interfere with breastfeeding. To substantially diminish the effect of the drug after using eye drops, place pressure over the tear duct by the corner of the eye for 1 minute or more, then remove the excess solution with an absorbent tissue.

I already used Zorcaine | Articaine Hydrochloride And Epinephrine Bitartrate Injection and meanwhile I breastfed my baby should I be concerned?

My doctor has prescribed me Zorcaine | Articaine Hydrochloride And Epinephrine Bitartrate Injection, what should I do?

If I am using Zorcaine | Articaine Hydrochloride And Epinephrine Bitartrate Injection, will my baby need extra monitoring?

Who can I talk to if I have questions about usage of Zorcaine | Articaine Hydrochloride And Epinephrine Bitartrate Injection in breastfeeding?