Prevpac | Lansoprazole, Amoxicillin And Clarithromycin Kit Breastfeeding
Most health expert recommend six month of exclusive breastfeeding but statics suggest that numbers are not good, almost 95% mothers start breastfeeding but this number drops to 40% in first three month and further it drops to 15% till fifth month. Sometime its due to need of medication usage. Because of these statics its important to provide good information on safety of drugs in breastfeeding so that it can be improved when possible. In this FAQ sheet we will discuss about exposure to Prevpac | Lansoprazole, Amoxicillin And Clarithromycin Kit while breastfeeding. We will also discuss about common side effects and warnings associated with Prevpac | Lansoprazole, Amoxicillin And Clarithromycin Kit.

What is Prevpac | Lansoprazole, Amoxicillin And Clarithromycin Kit used for?


H. pylori Eradication to Reduce the Risk of Duodenal Ulcer Recurrence The components in PREVPAC (PREVACID, amoxicillin, and clarithromycin) are indicated for the treatment of patients with H. pylori infection and duodenal ulcer disease (active or one-year history of a duodenal ulcer) to eradicate H. pylori. Eradication of H. pylori has been shown to reduce the risk of duodenal ulcer recurrence (see CLINICAL STUDIES and DOSAGE AND ADMINISTRATION). To reduce the development of drug-resistant bacteria and maintain the effectiveness of PREVPAC and other antibacterial drugs, PREVPAC should be used only to treat or prevent infections that are proven or strongly suspected to be caused by susceptible bacteria. When culture and susceptibility information are available, they should be considered in selecting or modifying antibacterial therapy. In the absence of such data, local epidemiology and susceptibility patterns may contribute to the empiric selection of therapy. Please refer to the full prescribing information for amoxicillin and clarithromycin.

Is Prevpac | Lansoprazole, Amoxicillin And Clarithromycin Kit safe to use while breastfeeding? Can it interfere with growth and development of my kid?

Prevpac | Lansoprazole, Amoxicillin And Clarithromycin Kit safe for breastfeeding
Prevpac | Lansoprazole, Amoxicillin And Clarithromycin Kit consists three active ingredients namely Lansoprazole,Amoxicillin and Clarithromycin. Our study of all three ingredients suggest that exposure of Prevpac | Lansoprazole, Amoxicillin And Clarithromycin Kit is mostly safe while breastfeeding. Although it is safe to use Prevpac | Lansoprazole, Amoxicillin And Clarithromycin Kit in lactation but also recommend you to go through the analysis of all three ingredients as below.

Statement of Manufacturer/Labeler about breastfeeding usage
Nursing Mothers Lansoprazole or its metabolites are excreted in the milk of rats. It is not known whether lansoprazole is excreted in human milk. Penicillins have been shown to be excreted in human milk. Amoxicillin use by nursing mothers may lead to sensitization of infants. Caution should be exercised when amoxicillin is administered to a nursing woman. It is not known whether clarithromycin is excreted in human milk. It is known that clarithromycin is excreted in the milk of lactating animals and that other drugs of this class are excreted in human milk. Due to the potential for serious adverse reactions in nursing infants from PREVPAC, and the potential for tumorigenicity shown for lansoprazole in rat carcinogenicity studies, a decision should be made whether to discontinue nursing or to discontinue PREVPAC, taking into account the importance of the therapy to the mother.

Prevpac | Lansoprazole, Amoxicillin And Clarithromycin Kit Breastfeeding Analsys


Lansoprazole while Breastfeeding

Safe

CAS Number: 103577-45-3

At latest update, relevant information on excretion into breast milk was not found. Due to a high serum-protein-binding capacity, excretion of Lansoprazole into breast milk is non-significant. Since it's neutralized by the acid pH of stomach, capsules with enteric coated granules are used. Because of this, it is thought that the small quantity of Lansoprazole that may reach the breast milk would be neutralized by infant's stomach. In addition, absorption is greatly decreased by the presence of food. Both Omeprazole and Pantoprazole pertain to the same chemical group with similar pharmacokinetics that are excreted in non-significant amount into the breast milk. Medication that has been used for treatment of newborn and premature infants. Hyperprolactinemia and galactorrhea have been reported by the use of such medication, though some authors have failed to show the same findings.

Amoxicillin while Breastfeeding

Safe

CAS Number: 26787-78-0

Excretion into breast milk is insignificant and no adverse effects reported in breasted infants. Es considerada medicación compatible con la lactancia por autores y sociedades científicas relevantes (Rowe 2013, Nahum 2006, Mahadevan 2006, Bar-Oz 2003, CDC 2001, Fulton 1992). Es una medicación de uso común en Pediatría y considerado medicamento esencial para uso pediátrico por la OMS (WHO 2013). The possible negativity of cultures in febrile infants whose mothers take antibiotics should be taken into account, as well as the possibility of gastroenteritis due to altered intestinal flora (Benyamini 2005, Ito 1993, Kafetzis 1981). American Academy of Pediatrics: medication usually compatible with breastfeeding (AAP 2001).List of WHO essential medicines: compatible with breastfeeding (WHO / UNICEF 2002).

Clarithromycin while Breastfeeding

Safe

CAS Number: 81103-11-9

It is not excreted in significant amount into breast milk . Commonly used for pediatric treatment which is very well tolerated. Erythromycin is a macrolide that has been related to hypertrophic pyloric stenosis with early exposition. Avoiding use in the first post-partum month would be advisable yet it may occurred while breastfeeding. Be aware of the possibility of false negative results of bacterial cultures when the mother is on antibiotics. Also, diarrheal disease due to imbalance of intestinal flora is possible.


Prevpac | Lansoprazole, Amoxicillin And Clarithromycin Kit Breastfeeding Analsys - 2


Lansoprazole while Breastfeeding

CAS Number: 103577-45-3

No information is available on the use of lansoprazole during breastfeeding. However, lansoprazole has been used safely in newborn infants, so it is unlikely that the amount in breastmilk would be harmful.

Amoxicillin while Breastfeeding

CAS Number: 26787-78-0

Limited information indicates that amoxicillin produces low levels in milk that are not expected to cause adverse effects in breastfed infants. Occasionally, rash and disruption of the infant's gastrointestinal flora, resulting in diarrhea or thrush, have been reported, but these effects have not been adequately evaluated. Amoxicillin is acceptable in nursing mothers. Amoxicillin powder for suspension reconstituted with breastmilk is absorbed as well as the powder reconstituted with water.[1]

Clarithromycin while Breastfeeding

CAS Number: 81103-11-9

Because of the low levels of clarithromycin in breastmilk and administration directly to infants, it is acceptable in nursing mothers. The small amounts in milk are unlikely to cause adverse effects in the infant. Monitor the infant for possible effects on the gastrointestinal flora, such as diarrhea, candidiasis (thrush, diaper rash). Unconfirmed epidemiologic evidence indicates that the risk of hypertrophic pyloric stenosis in infants might be increased by maternal use of macrolide antibiotics during breastfeeding.



What should I do if already breastfed my kid after using Prevpac | Lansoprazole, Amoxicillin And Clarithromycin Kit?

As usage of Prevpac | Lansoprazole, Amoxicillin And Clarithromycin Kit is mostly safe while breastfeeding hence there should not be any concern. In case of any change in behavior or health of your baby you should inform your health care provider about usage of Prevpac | Lansoprazole, Amoxicillin And Clarithromycin Kit else no further action is required.


My health care provider has asked me to use Prevpac | Lansoprazole, Amoxicillin And Clarithromycin Kit, what to do?

Usage of Prevpac | Lansoprazole, Amoxicillin And Clarithromycin Kit is safe for nursing mothers and baby, No worries.


If I am using Prevpac | Lansoprazole, Amoxicillin And Clarithromycin Kit, will my baby need extra monitoring?

No


Who can I talk to if I have questions about usage of Prevpac | Lansoprazole, Amoxicillin And Clarithromycin Kit in breastfeeding?

US
National Womens Health and Breastfeeding Helpline: 800-994-9662 (TDD 888-220-5446) 9 a.m. and 6 p.m. ET, Monday through Friday

UK
National Breastfeeding Helpline: 0300-100-0212 9.30am to 9.30pm, daily
Association of Breastfeeding Mothers: 0300-330-5453
La Leche League: 0345-120-2918
The Breastfeeding Network supporter line in Bengali and Sylheti: 0300-456-2421
National Childbirth Trust (NCT): 0300-330-0700

Australia
National Breastfeeding Helpline: 1800-686-268 24 hours a day, 7 days a week

Canada
Telehealth Ontario for breastfeeding: 1-866-797-0000 24 hours a day, 7 days a week