Onexton | Clindamycin Phosphate And Benzoyl Peroxide Gel while Breastfeeding
American Academy of Pediatrics and other medical experts exclusively recommend to breastfeed the baby for first 6 months. Once you introduce baby to other foods it is recommended to breastfeed for at least first year of babys life. Taking medication while breastfeeding could be tricky as most drugs pass in breast milk. In this article we will evaluate Onexton | Clindamycin Phosphate And Benzoyl Peroxide Gel for its safety in breastfeeding.

What is Onexton | Clindamycin Phosphate And Benzoyl Peroxide Gel used for?


ONEXTON® (clindamycin phosphate and benzoyl peroxide) Gel, 1.2%/3.75% is indicated for the topical treatment of acne vulgaris in patients 12 years of age and older. ONEXTON Gel is a combination of clindamycin phosphate (a lincosamide antibacterial) and benzoyl peroxide indicated for the topical treatment of acne vulgaris in patients 12 years of age and older. (1)

Is Onexton | Clindamycin Phosphate And Benzoyl Peroxide Gel safe to use while breastfeeding? Can it interfere with growth and development of my kid?

Onexton | Clindamycin Phosphate And Benzoyl Peroxide Gel low risk for breastfeeding
Clindamycin and Benzoyl peroxide are the two main ingredients of Onexton | Clindamycin Phosphate And Benzoyl Peroxide Gel. Based on our individual analysis of Clindamycin and Benzoyl peroxide we can safely say that Onexton | Clindamycin Phosphate And Benzoyl Peroxide Gel has low risk while breastfeeding. Below we have summarized the usage of Clindamycin and Benzoyl peroxide while breastfeeding, we recommend you to go through it for better understanding of your usage.

Statement of Manufacturer/Labeler about breastfeeding usage
8.3 Nursing Mothers It is not known whether clindamycin is excreted in human milk after topical application of ONEXTON Gel. However, orally and parenterally administered clindamycin has been reported to appear in breast milk. Because of the potential for serious adverse reactions in nursing infants, a decision should be made whether to use ONEXTON Gel while nursing, taking into account the importance of the drug to the mother.

Onexton | Clindamycin Phosphate And Benzoyl Peroxide Gel Breastfeeding Analsys


Clindamycin while Breastfeeding

Low Risk

CAS Number: 18323-44-9

Lincosamide antibacterial. Excreted in non-significant level into breast milk. Except for few cases of enterocolitis due to disturbance of intestinal flora no other harm effects have been shown in breastfed infants. All cases spontaneously cured after discontinuation of medication. One reported case (1980) of pseudomembrane colitis in an infant whose mother was on clindamicin and gentamicin. Be aware of the possibility of false negative results of febrile infant bacterial cultures when the mother is on antibiotics and diarrheal disease due to intestinal flora imbalance. The American Academy of Pediatrics rates it as compatible with breastfeeding.

Benzoyl peroxide while Breastfeeding

Safe

CAS Number: 94-36-0

A keratolytic and topical anti-infective agent used in the treatment of acne. Since the last update we have not found published data on its excretion in breast milk Only 5% is absorbed through the skin and is quickly eliminated via urine after being metabolized in the skin to benzoic acid (AEMPS 2013, Seubert 1984, Holzmann 1979), so it is not expected to pass into breast milk.Taken orally, it is destroyed at the gastrointestinal level, so its absorption into milk is zero. It is considered very low risk during breastfeeding (Kong 2013, Worret 2006, Leachman 2006, Zip 2002). Do not apply to the chest in order to prevent the infant from ingesting it; if necessary, apply after breastfeeding and clean well with water before the next feed. Applying topical creams, gels and other products which contain paraffin (mineral oil) to the nipple is to be avoided so that the infant does not absorb them. (Concin 2008, Noti 2003). List of essential medicines WHO: compatible with breastfeeding (WHO / UNICEF 2002).


Onexton | Clindamycin Phosphate And Benzoyl Peroxide Gel Breastfeeding Analsys - 2


Clindamycin while Breastfeeding

CAS Number: 18323-44-9

Clindamycin has the potential to cause adverse effects on the breastfed infant's gastrointestinal flora. If oral or intravenous clindamycin is required by a nursing mother, it is not a reason to discontinue breastfeeding, but an alternate drug may be preferred. Monitor the infant for possible effects on the gastrointestinal flora, such as diarrhea, candidiasis (thrush, diaper rash) or rarely, blood in the stool indicating possible antibiotic-associated colitis. Vaginal application is unlikely to cause infant side effects, although about 30% of a vaginal dose is absorbed. Infant side effects are unlikely with topical administration for acne; however, topical application to the breast may increase the risk of diarrhea if it is ingested by the infant. Only water-miscible cream, foam, gel or liquid products should be applied to the breast because ointments may expose the infant to high levels of mineral paraffins via licking.[1]

Benzoyl peroxide while Breastfeeding

CAS Number: 94-36-0

Topical benzoyl peroxide has not been studied during breastfeeding. Because only about 5% is absorbed following topical application, it is considered a low risk to the nursing infant.[1][2] Ensure that the infant's skin does not come into direct contact with the areas of skin that have been treated. Only water-miscible cream or gel products should be applied to the breast because ointments may expose the infant to high levels of mineral paraffins via licking.[3]



I already used Onexton | Clindamycin Phosphate And Benzoyl Peroxide Gel and meanwhile I breastfed my baby should I be concerned?

During whole lactation period you shall first discuss with your doctor and then together you shall decide whether you shall take that drug or not however if you have already taken Onexton | Clindamycin Phosphate And Benzoyl Peroxide Gel then you shall inform your doctor, But you should not be worried too much as Onexton | Clindamycin Phosphate And Benzoyl Peroxide Gel comes in category of low risk drug.


My health care provider has asked me to use Onexton | Clindamycin Phosphate And Benzoyl Peroxide Gel, what to do?

Though Onexton | Clindamycin Phosphate And Benzoyl Peroxide Gel dose not comes in category of safe drugs rather it comes in category of low risk but if your doctor is aware that you are breastfeeding your baby and has still recommended it then its advantages must be outweighing the risks.


If I am using Onexton | Clindamycin Phosphate And Benzoyl Peroxide Gel, will my baby need extra monitoring?

Not much


Who can I talk to if I have questions about usage of Onexton | Clindamycin Phosphate And Benzoyl Peroxide Gel in breastfeeding?

US
National Womens Health and Breastfeeding Helpline: 800-994-9662 (TDD 888-220-5446) 9 a.m. and 6 p.m. ET, Monday through Friday

UK
National Breastfeeding Helpline: 0300-100-0212 9.30am to 9.30pm, daily
Association of Breastfeeding Mothers: 0300-330-5453
La Leche League: 0345-120-2918
The Breastfeeding Network supporter line in Bengali and Sylheti: 0300-456-2421
National Childbirth Trust (NCT): 0300-330-0700

Australia
National Breastfeeding Helpline: 1800-686-268 24 hours a day, 7 days a week

Canada
Telehealth Ontario for breastfeeding: 1-866-797-0000 24 hours a day, 7 days a week

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